Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors K Skrenkova, K Hemelikova, M Kolcheva, S Kortus, M Kaniakova, ... Scientific reports 9 (1), 12303, 2019 | 24 | 2019 |
The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors K Skrenkova, J Song, S Kortus, M Kolcheva, J Netolicky, K Hemelikova, ... Scientific Reports 10 (1), 18576, 2020 | 16 | 2020 |
Specific pathogenic mutations in the M3 domain of the GluN1 subunit regulate the surface delivery and pharmacological sensitivity of NMDA receptors M Kolcheva, S Kortus, BH Krausova, P Barackova, A Misiachna, ... Neuropharmacology 189, 108528, 2021 | 14 | 2021 |
Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors L Gorecki, A Misiachna, J Damborsky, R Dolezal, J Korabecny, L Cejkova, ... European Journal of Medicinal Chemistry 219, 113434, 2021 | 12 | 2021 |
Lectins modulate the functional properties of GluN1/GluN3-containing NMDA receptors K Hemelikova, M Kolcheva, K Skrenkova, M Kaniakova, M Horak Neuropharmacology 157, 107671, 2019 | 11 | 2019 |
The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors M Kolcheva, M Ladislav, J Netolicky, S Kortus, K Rehakova, BH Krausova, ... Neuropharmacology 222, 109297, 2023 | 8 | 2023 |
Pursuing the Complexity of Alzheimer’s Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor … J Konecny, A Misiachna, M Hrabinova, L Pulkrabkova, M Benkova, ... Biomolecules 11 (1), 3, 2020 | 5 | 2020 |
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition A Misiachna, B Svobodova, J Netolicky, M Chvojkova, L Kleteckova, ... European Journal of Medicinal Chemistry 266, 116130, 2024 | 1 | 2024 |
Subunit-dependent surface mobility and localization of NMDA receptors in hippocampal neurons measured using nanobody probes S Kortus, K Rehakova, M Klima, M Kolcheva, M Ladislav, E Langore, ... Journal of Neuroscience 43 (26), 4755-4774, 2023 | 1 | 2023 |
Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer’s Disease B Svobodova, L Pulkrabkova, D Panek, A Misiachna, M Kolcheva, ... International Journal of Molecular Sciences 24 (11), 9124, 2023 | 1 | 2023 |
Functional and pharmacological properties of GluN1/GluN2 and GluN1/GluN3 subtypes of NMDA receptors M Kolcheva Univerzita Karlova, Přírodovědecká fakulta, 2023 | 1 | 2023 |
Potent and reversible open-channel blocker of NMDA receptor derived from dizocilpine with enhanced membrane-to-channel inhibition A Misiachna, J Konecny, M Kolcheva, M Ladislav, L Prchal, J Netolicky, ... bioRxiv, 2024.04. 15.589518, 2024 | | 2024 |
Independent regulation of early trafficking of NMDA receptors by ligand-binding domains of the GluN1 and GluN2A subunits J Netolicky, P Zahumenska, A Misiachna, M Kolcheva, T Kucera, J Fibigar, ... bioRxiv, 2024.02. 02.578575, 2024 | | 2024 |
A NEW SERIES OF PHARMACOLOGICAL DRUGS ACTING AT GLUN1/GLUN2A AND GLUN1/GLUN2B NMDA RECEPTORS M Horak, A Misiachna, M Kolcheva, J Korabecny, O Soukup IBRO Neuroscience Reports 15, S426-S427, 2023 | | 2023 |
N-glycosylation regulates the trafficking, surface mobility and function of GluN3A-containing NMDA receptors M Horak, K Skrenkova, M Zapotocky, M Kolcheva, K Hemelikova, ... IBRO Reports 6, S533, 2019 | | 2019 |
Signal ways of hypoxia-induced cardioprotection in diabetic heart A Portnychenko, M Vasylenko, V Babicheva, T Lapikova-Bryhinska, ... CARDIOVASCULAR RESEARCH 114, S128-S128, 2018 | | 2018 |
Hypoxic preconditioning and metabolic rebuilding in heart ventricles of diabetic rats A Portnychenko, M Vasylenko, T Lapikova-Bryhinska, M Kolcheva, ... EUROPEAN HEART JOURNAL 38, 339-340, 2017 | | 2017 |
2. Physicochemical properties–Lipinski’s rule of five and the BBB score L Gorecki, A Misiachna, J Damborsky, R Dolezal, J Korabecny, L Cejkova, ... | | |
IGF-1-dependent Protective Mechanisms under Hypoxia and Experimental Diabetes AG Portnychenko, MI Vasylenko, TY Lapikova-Briginska, VV Babicheva, ... | | |