|From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites|
A Koh, F De Vadder, P Kovatcheva-Datchary, F Bäckhed
Cell 165 (6), 1332-1345, 2016
|Microbially produced imidazole propionate impairs insulin signaling through mTORC1|
A Koh, A Molinaro, M Ståhlman, MT Khan, C Schmidt, L Mannerås-Holm, ...
Cell 175 (4), 947-961. e17, 2018
|Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition|
D Park, H Jeong, MN Lee, A Koh, O Kwon, YR Yang, J Noh, PG Suh, ...
Scientific reports 6 (1), 21772, 2016
|O‐GlcNAcase is essential for embryonic development and maintenance of genomic stability|
YR Yang, M Song, H Lee, Y Jeon, EJ Choi, HJ Jang, HY Moon, HY Byun, ...
Aging cell 11 (3), 439-448, 2012
|Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb|
MN Lee, SH Ha, J Kim, A Koh, CS Lee, JH Kim, H Jeon, DH Kim, PG Suh, ...
Molecular and cellular biology 29 (14), 3991-4001, 2009
|From association to causality: the role of the gut microbiota and its functional products on host metabolism|
A Koh, F Bäckhed
Molecular cell 78 (4), 584-596, 2020
|Microbial imidazole propionate affects responses to metformin through p38γ-dependent inhibitory AMPK phosphorylation|
A Koh, L Mannerås-Holm, NO Yunn, PM Nilsson, SH Ryu, A Molinaro, ...
Cell metabolism 32 (4), 643-653. e4, 2020
|Agonistic aptamer to the insulin receptor leads to biased signaling and functional selectivity through allosteric modulation|
NO Yunn, A Koh, S Han, JH Lim, S Park, J Lee, E Kim, SK Jang, ...
Nucleic acids research 43 (16), 7688-7701, 2015
|C1-Ten is a protein tyrosine phosphatase of insulin receptor substrate 1 (IRS-1), regulating IRS-1 stability and muscle atrophy|
A Koh, MN Lee, YR Yang, H Jeong, J Ghim, J Noh, J Kim, D Ryu, S Park, ...
Molecular and cellular biology 33 (8), 1608-1620, 2013
|Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice|
YR Yang, HJ Jang, SS Choi, YH Lee, GH Lee, YK Seo, JH Choi, D Park, ...
Diabetologia 58, 2867-2876, 2015
|Apolipoprotein a1 increases mitochondrial biogenesis through AMP-activated protein kinase|
P Song, Y Kwon, K Yea, HY Moon, JH Yoon, J Ghim, H Hyun, D Kim, ...
Cellular Signalling 27 (9), 1873-1881, 2015
|Parkin ubiquitinates mTOR to regulate mTORC1 activity under mitochondrial stress|
D Park, MN Lee, H Jeong, A Koh, YR Yang, PG Suh, SH Ryu
Cellular signalling 26 (10), 2122-2130, 2014
|Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways|
H Jeong, A Koh, J Lee, D Park, JO Lee, MN Lee, KJ Jo, HNK Tran, E Kim, ...
Scientific reports 7 (1), 17777, 2017
|C1-Ten is a PTPase of nephrin, regulating podocyte hypertrophy through mTORC1 activation|
J Lee, A Koh, H Jeong, E Kim, TS Ha, MA Saleem, SH Ryu
Scientific reports 7 (1), 12346, 2017
|Hepatic expression of lipopolysaccharide-binding protein (Lbp) is induced by the gut microbiota through Myd88 and impairs glucose tolerance in mice independent of obesity|
A Molinaro, A Koh, H Wu, M Schoeler, MI Faggi, A Carreras, A Hallén, ...
Molecular Metabolism 37, 100997, 2020
|Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3, 4, 5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain|
E Kim, DH Kim, I Singaram, H Jeong, A Koh, J Lee, W Cho, SH Ryu
Cellular signalling 51, 130-138, 2018
|Vibrio vulnificus secretes an insulin-degrading enzyme that promotes bacterial proliferation in vivo|
IH Kim, IJ Kim, Y Wen, NY Park, J Park, KW Lee, A Koh, JH Lee, SH Koo, ...
Journal of Biological Chemistry 290 (30), 18708-18720, 2015
|Deacetylated αβ-tubulin acts as a positive regulator of Rheb GTPase through increasing its GTP-loading|
MN Lee, A Koh, D Park, JH Jang, D Kwak, H Jeon, J Kim, EJ Choi, ...
Cellular Signalling 25 (2), 539-551, 2013
|Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production|
R Venskutonytė, A Koh, O Stenström, MT Khan, A Lundqvist, M Akke, ...
Nature communications 12 (1), 1347, 2021
|Liver-specific RORα deletion does not affect the metabolic susceptibility to western style diet feeding|
A Molinaro, R Caesar, L L'homme, A Koh, M Ståhlman, B Staels, ...
Molecular metabolism 23, 82-87, 2019