From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites A Koh, F De Vadder, P Kovatcheva-Datchary, F Bäckhed Cell 165 (6), 1332-1345, 2016 | 5446 | 2016 |
Microbially produced imidazole propionate impairs insulin signaling through mTORC1 A Koh, A Molinaro, M Ståhlman, MT Khan, C Schmidt, L Mannerås-Holm, ... Cell 175 (4), 947-961. e17, 2018 | 657 | 2018 |
Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition D Park, H Jeong, MN Lee, A Koh, O Kwon, YR Yang, J Noh, PG Suh, ... Scientific reports 6 (1), 21772, 2016 | 292 | 2016 |
O‐GlcNAcase is essential for embryonic development and maintenance of genomic stability YR Yang, M Song, H Lee, Y Jeon, EJ Choi, HJ Jang, HY Moon, HY Byun, ... Aging cell 11 (3), 439-448, 2012 | 260 | 2012 |
From association to causality: the role of the gut microbiota and its functional products on host metabolism A Koh, F Bäckhed Molecular cell 78 (4), 584-596, 2020 | 257 | 2020 |
Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb MN Lee, SH Ha, J Kim, A Koh, CS Lee, JH Kim, H Jeon, DH Kim, PG Suh, ... Molecular and cellular biology 29 (14), 3991-4001, 2009 | 209 | 2009 |
Microbial imidazole propionate affects responses to metformin through p38γ-dependent inhibitory AMPK phosphorylation A Koh, L Mannerås-Holm, NO Yunn, PM Nilsson, SH Ryu, A Molinaro, ... Cell metabolism 32 (4), 643-653. e4, 2020 | 106 | 2020 |
Agonistic aptamer to the insulin receptor leads to biased signaling and functional selectivity through allosteric modulation NO Yunn, A Koh, S Han, JH Lim, S Park, J Lee, E Kim, SK Jang, ... Nucleic acids research 43 (16), 7688-7701, 2015 | 62 | 2015 |
C1-Ten is a protein tyrosine phosphatase of insulin receptor substrate 1 (IRS-1), regulating IRS-1 stability and muscle atrophy A Koh, MN Lee, YR Yang, H Jeong, J Ghim, J Noh, J Kim, D Ryu, S Park, ... Molecular and cellular biology, 2013 | 48 | 2013 |
Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice YR Yang, HJ Jang, SS Choi, YH Lee, GH Lee, YK Seo, JH Choi, D Park, ... Diabetologia 58, 2867-2876, 2015 | 39 | 2015 |
Apolipoprotein a1 increases mitochondrial biogenesis through AMP-activated protein kinase P Song, Y Kwon, K Yea, HY Moon, JH Yoon, J Ghim, H Hyun, D Kim, ... Cellular signalling 27 (9), 1873-1881, 2015 | 28 | 2015 |
Parkin ubiquitinates mTOR to regulate mTORC1 activity under mitochondrial stress D Park, MN Lee, H Jeong, A Koh, YR Yang, PG Suh, SH Ryu Cellular signalling 26 (10), 2122-2130, 2014 | 23 | 2014 |
Hepatic expression of lipopolysaccharide-binding protein (Lbp) is induced by the gut microbiota through Myd88 and impairs glucose tolerance in mice independent of obesity A Molinaro, A Koh, H Wu, M Schoeler, MI Faggi, A Carreras, A Hallén, ... Molecular Metabolism 37, 100997, 2020 | 21 | 2020 |
Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways H Jeong, A Koh, J Lee, D Park, JO Lee, MN Lee, KJ Jo, HNK Tran, E Kim, ... Scientific reports 7 (1), 17777, 2017 | 19 | 2017 |
C1-Ten is a PTPase of nephrin, regulating podocyte hypertrophy through mTORC1 activation J Lee, A Koh, H Jeong, E Kim, TS Ha, MA Saleem, SH Ryu Scientific reports 7 (1), 12346, 2017 | 15 | 2017 |
Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production R Venskutonytė, A Koh, O Stenström, MT Khan, A Lundqvist, M Akke, ... Nature communications 12 (1), 1347, 2021 | 14 | 2021 |
Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3, 4, 5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain E Kim, DH Kim, I Singaram, H Jeong, A Koh, J Lee, W Cho, SH Ryu Cellular signalling 51, 130-138, 2018 | 13 | 2018 |
Approaching precision medicine by tailoring the microbiota G Ryu, H Kim, A Koh Mammalian Genome 32, 206-222, 2021 | 9 | 2021 |
Vibrio vulnificus secretes an insulin-degrading enzyme that promotes bacterial proliferation in vivo IH Kim, IJ Kim, Y Wen, NY Park, J Park, KW Lee, A Koh, JH Lee, SH Koo, ... Journal of Biological Chemistry 290 (30), 18708-18720, 2015 | 9 | 2015 |
From the dish to the real world: modeling interactions between the gut and microorganisms in gut organoids by tailoring the gut milieu NY Park, A Koh International Journal of Stem Cells 15 (1), 70-84, 2022 | 8 | 2022 |