| The Caco-2 cell monolayer: usefulness and limitations H Sun, ECY Chow, S Liu, Y Du, KS Pang Expert opinion on drug metabolism & toxicology 4 (4), 395-411, 2008 | 547 | 2008 |
| Highly selective inhibition of tyrosine kinase 2 (TYK2) for the treatment of autoimmune diseases: discovery of the allosteric inhibitor BMS-986165 ST Wrobleski, R Moslin, S Lin, Y Zhang, S Spergel, J Kempson, ... Journal of Medicinal Chemistry 62 (20), 8973-8995, 2019 | 258 | 2019 |
| Permeability, transport, and metabolism of solutes in Caco-2 cell monolayers: a theoretical study H Sun, KS Pang Drug Metabolism and Disposition 36 (1), 102-123, 2008 | 149 | 2008 |
| Effects of 1α,25‐dihydroxyvitamin D3 on transporters and enzymes of the rat intestine and kidney in vivo ECY Chow, H Sun, AA Khan, GMM Groothuis, KS Pang Biopharmaceutics & drug disposition 31 (1), 91-108, 2010 | 74 | 2010 |
| Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of … R Moslin, Y Zhang, ST Wrobleski, S Lin, M Mertzman, S Spergel, ... Journal of Medicinal Chemistry 62 (20), 8953-8972, 2019 | 67 | 2019 |
| A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokines Q Zhao, T Kim, J Pang, W Sun, X Yang, J Wang, Y Song, H Zhang, H Sun, ... Journal of leukocyte biology 102 (5), 1271-1280, 2017 | 61 | 2017 |
| Identification of imidazo [1, 2-b] pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling R Moslin, D Gardner, J Santella, Y Zhang, JV Duncia, C Liu, J Lin, ... Medchemcomm 8 (4), 700-712, 2017 | 49 | 2017 |
| Formed and preformed metabolites: facts and comparisons KS Pang, ME Morris, H Sun Journal of Pharmacy and Pharmacology 60 (10), 1247-1275, 2008 | 49 | 2008 |
| A Novel, Fully Human Anti–fucosyl-GM1 Antibody Demonstrates Potent In Vitro and In Vivo Antitumor Activity in Preclinical Models of Small Cell Lung Cancer P Ponath, D Menezes, C Pan, B Chen, M Oyasu, D Strachan, H LeBlanc, ... Clinical Cancer Research 24 (20), 5178-5189, 2018 | 48 | 2018 |
| Influence of P-glycoprotein, transfer clearances, and drug binding on intestinal metabolism in Caco-2 cell monolayers or membrane preparations: a theoretical analysis D Tam, H Sun, KS Pang Drug metabolism and disposition 31 (10), 1214-1226, 2003 | 47 | 2003 |
| Identification of Imidazo[1,2-b]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors C Liu, J Lin, R Moslin, JS Tokarski, J Muckelbauer, CY Chang, J Tredup, ... ACS Medicinal Chemistry Letters 10 (3), 383-388, 2019 | 42 | 2019 |
| Antibody–drug conjugate bioanalysis using LB-LC–MS/MS hybrid assays: strategies, methodology and correlation to ligand-binding assays J Wang, H Gu, A Liu, A Kozhich, V Rangan, H Myler, L Luo, R Wong, ... Bioanalysis 8 (13), 1383-1401, 2016 | 38 | 2016 |
| A catenary model to study transport and conjugation of baicalein, a bioactive flavonoid, in the Caco-2 cell monolayer: demonstration of substrate inhibition H Sun, L Zhang, ECY Chow, G Lin, Z Zuo, KS Pang Journal of Pharmacology and Experimental Therapeutics 326 (1), 117-126, 2008 | 38 | 2008 |
| Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure … H Gong, DS Weinstein, Z Lu, JJW Duan, S Stachura, L Haque, ... Bioorganic & medicinal chemistry letters 28 (2), 85-93, 2018 | 36 | 2018 |
| Physiological modeling to understand the impact of enzymes and transporters on drug and metabolite data and bioavailability estimates H Sun, KS Pang Pharmaceutical research 27, 1237-1254, 2010 | 36 | 2010 |
| Liquid chromatography coupled with tandem mass spectrometry for the bioanalysis of proteins in drug development: practical considerations in assay development and validation G Liu, QC Ji, R Dodge, H Sun, D Shuster, Q Zhao, M Arnold Journal of chromatography A 1284, 155-162, 2013 | 34 | 2013 |
| Interplay of phase II enzymes and transporters in futile cycling: influence of multidrug resistance-associated protein 2-mediated excretion of estradiol 17β-d-glucuronide and … H Sun, YY Zeng, KS Pang Drug metabolism and disposition 38 (5), 769-780, 2010 | 28 | 2010 |
| Vitamin D receptor activation induces P-glycoprotein and increases brain efflux of quinidine: an intracerebral microdialysis study in conscious rats MR Durk, J Fan, H Sun, Y Yang, H Pang, KS Pang, IAM de Lannoy Pharmaceutical research 32, 1128-1140, 2015 | 26 | 2015 |
| Immunoaffinity LC–MS/MS for quantitative determination of a free and total protein target as a target engagement biomarker H Zhang, H Gu, P Shipkova, E Ciccimaro, H Sun, Q Zhao, TV Olah Bioanalysis 9 (20), 1573-1588, 2017 | 24 | 2017 |
| Disparity in intestine disposition between formed and preformed metabolites and implications: a theoretical study H Sun, KS Pang Drug metabolism and disposition 37 (1), 187-202, 2009 | 23 | 2009 |
