Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2 DA Collier, IATM Ferreira, P Kotagiri, RP Datir, EY Lim, E Touizer, B Meng, ... Nature 596 (7872), 417-422, 2021 | 636 | 2021 |
PPARγ agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation E Legchenko, P Chouvarine, P Borchert, A Fernandez-Gonzalez, E Snay, ... Science translational medicine 10 (438), eaao0303, 2018 | 230 | 2018 |
PPARγ links BMP2 and TGFβ1 pathways in vascular smooth muscle cells, regulating cell proliferation and glucose metabolism L Calvier, P Chouvarine, E Legchenko, N Hoffmann, J Geldner, ... Cell metabolism 25 (5), 1118-1134. e7, 2017 | 201 | 2017 |
Galectin-3 and aldosterone as potential tandem biomarkers in pulmonary arterial hypertension L Calvier, E Legchenko, L Grimm, H Sallmon, A Hatch, BD Plouffe, ... Heart 102 (5), 390-396, 2016 | 106 | 2016 |
Combined point-of-care nucleic acid and antibody testing for SARS-CoV-2 following emergence of D614G spike variant P Mlcochova, D Collier, A Ritchie, SM Assennato, M Hosmillo, N Goel, ... Cell Reports Medicine 1 (6), 2020 | 83 | 2020 |
Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb D Köhler, T Granja, J Volz, M Koeppen, HF Langer, G Hansmann, ... Nature communications 11 (1), 1315, 2020 | 50 | 2020 |
PPARγ is a gatekeeper for extracellular matrix and vascular cell homeostasis: beneficial role in pulmonary hypertension and renal/cardiac/pulmonary fibrosis G Kökény, L Calvier, E Legchenko, P Chouvarine, MM Mózes, ... Current opinion in nephrology and hypertension 29 (2), 171-179, 2020 | 46 | 2020 |
Hypoxia drives cardiac miRNAs and inflammation in the right and left ventricle P Chouvarine, E Legchenko, J Geldner, C Riehle, G Hansmann Journal of Molecular Medicine 97, 1427-1438, 2019 | 41 | 2019 |
SARS-CoV-2 Omicron spike mediated immune escape and tropism shift B Meng, IATM Ferreira, A Abdullahi, N Goonawardane, A Saito, I Kimura, ... BioRxiv, 2021.12. 17.473248, 2021 | 35 | 2021 |
SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity B Meng, R Datir, J Choi, S Baker, G Dougan, C Hess, N Kingston, ... Cell Reports 40 (7), 2022 | 27 | 2022 |
Trans-right–ventricle and transpulmonary MicroRNA gradients in human pulmonary arterial hypertension P Chouvarine, J Geldner, R Giagnorio, E Legchenko, H Bertram, ... Pediatric Critical Care Medicine 21 (4), 340-349, 2020 | 25 | 2020 |
Chronic TGF-β1 signaling in pulmonary arterial hypertension induces sustained canonical Smad3 pathways in vascular smooth muscle cells L Calvier, P Chouvarine, E Legchenko, G Kokeny, MM Mozes, ... American journal of respiratory cell and molecular biology 61 (1), 121-123, 2019 | 19 | 2019 |
Emerging therapies for right ventricular dysfunction and failure A Klinke, T Schubert, M Müller, E Legchenko, JGE Zelt, T Shimauchi, ... Cardiovascular Diagnosis and Therapy 10 (5), 1735, 2020 | 17 | 2020 |
Transforming growth factor β1–and bone morphogenetic protein 2/PPARγ–regulated microRNAs in pulmonary arterial hypertension L Calvier, P Chouvarine, E Legchenko, G Hansmann American journal of respiratory and critical care medicine 196 (9), 1227-1228, 2017 | 16 | 2017 |
Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups L Hurler, Á Szilágyi, F Mescia, L Bergamaschi, B Mező, G Sinkovits, ... Frontiers in immunology 14, 1162171, 2023 | 13 | 2023 |
Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs L Hurler, EJM Toonen, E Kajdácsi, B van Bree, RJ Brandwijk, W de Bruin, ... Frontiers in immunology 13, 1039765, 2022 | 12 | 2022 |
Emphysema Is—at the Most—Only a Mild Phenotype in the Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension HJ Bogaard, E Legchenko, KR Chaudhary, XQ Sun, DJ Stewart, ... American journal of respiratory and critical care medicine 200 (11), 1447-1450, 2019 | 11 | 2019 |
PPARgamma agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation. Sci Transl Med. 2018 E Legchenko, P Chouvarine, P Borchert, A Fernandez-Gonzalez, E Snay, ... Epub 2018/04/27. https://doi. org/10.1126/scitranslmed. aao0303, 0 | 11 | |
Soluble Receptor for Advanced Glycation End Products (sRAGE) is a sensitive biomarker in human pulmonary arterial hypertension F Diekmann, P Chouvarine, H Sallmon, L Meyer-Kobbe, M Kieslich, ... International Journal of Molecular Sciences 22 (16), 8591, 2021 | 10 | 2021 |
Human umbilical cord mesenchymal stem cell-derived treatment of severe pulmonary arterial hypertension G Hansmann, P Chouvarine, F Diekmann, M Giera, M Ralser, M Mülleder, ... Nature Cardiovascular Research 1 (6), 568-576, 2022 | 9 | 2022 |