Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors W Zhang, SL Yang, M Yang, S Herrlinger, Q Shao, JL Collar, E Fierro, ... Nature communications 10 (1), 2612, 2019 | 173 | 2019 |
Specific gene-regulation networks during the pre-implantation development of the pig embryo as revealed by deep sequencing S Cao, J Han, J Wu, Q Li, S Liu, W Zhang, Y Pei, X Ruan, Z Liu, X Wang, ... BMC genomics 15, 1-13, 2014 | 143 | 2014 |
Cerebral organoid and mouse models reveal a RAB39b–PI3K–mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes W Zhang, L Ma, M Yang, Q Shao, J Xu, Z Lu, Z Zhao, R Chen, Y Chai, ... Genes & development 34 (7-8), 580-597, 2020 | 121 | 2020 |
C9orf72 deficiency promotes motor deficits of a C9ALS/FTD mouse model in a dose-dependent manner Q Shao, C Liang, Q Chang, W Zhang, M Yang, JF Chen Acta neuropathologica communications 7, 1-3, 2019 | 75 | 2019 |
Induction of germ cell-like cells from porcine induced pluripotent stem cells H Wang, J Xiang, W Zhang, J Li, Q Wei, L Zhong, H Ouyang, J Han Scientific reports 6 (1), 27256, 2016 | 57 | 2016 |
C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis Q Shao, M Yang, C Liang, L Ma, W Zhang, Z Jiang, J Luo, JK Lee, ... Autophagy 16 (9), 1635-1650, 2020 | 55 | 2020 |
Pluripotent and metabolic features of two types of porcine iPSCs derived from defined mouse and human ES cell culture conditions W Zhang, Y Pei, L Zhong, B Wen, S Cao, J Han PloS one 10 (4), e0124562, 2015 | 38 | 2015 |
Mthfd2 modulates mitochondrial function and DNA repair to maintain the pluripotency of mouse stem cells L Yue, Y Pei, L Zhong, H Yang, Y Wang, W Zhang, N Chen, Q Zhu, J Gao, ... Stem Cell Reports 15 (2), 529-545, 2020 | 33 | 2020 |
Highly efficient generation of biallelic reporter gene knock-in mice via CRISPR-mediated genome editing of ESCs Y Wang, J Li, J Xiang, B Wen, H Mu, W Zhang, J Han Protein & Cell 7 (2), 152-156, 2016 | 27 | 2016 |
Evidence of IgY subclass diversification in snakes: evolutionary implications T Wang, Y Sun, W Shao, G Cheng, L Li, Z Cao, Z Yang, H Zou, W Zhang, ... The Journal of Immunology 189 (7), 3557-3565, 2012 | 24 | 2012 |
Overcoming barriers to the clinical utilization of iPSCs: reprogramming efficiency, safety and quality S Cao, K Loh, Y Pei, W Zhang, J Han Protein & cell 3, 834-845, 2012 | 23 | 2012 |
Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models C Liang, Q Shao, W Zhang, M Yang, Q Chang, R Chen, JF Chen Human molecular genetics 28 (23), 3940-3953, 2019 | 18 | 2019 |
Lipid supplement in the cultural condition facilitates the porcine iPSC derivation through cAMP/PKA/CREB signal pathway W Zhang, H Wang, S Zhang, L Zhong, Y Wang, Y Pei, J Han, S Cao International Journal of Molecular Sciences 19 (2), 509, 2018 | 18 | 2018 |
Improvement in mouse iPSC induction by Rab32 reveals the importance of lipid metabolism during reprogramming Y Pei, L Yue, W Zhang, Y Wang, B Wen, L Zhong, J Xiang, J Li, S Zhang, ... Scientific reports 5 (1), 16539, 2015 | 18 | 2015 |
Long non-coding RNAs involved in the regulatory network during porcine pre-implantation embryonic development and iPSC induction L Zhong, H Mu, B Wen, W Zhang, Q Wei, G Gao, J Han, S Cao Scientific reports 8 (1), 1-15, 2018 | 16 | 2018 |
Distinct microRNA expression signatures of porcine induced pluripotent stem cells under mouse and human ESC culture conditions W Zhang, L Zhong, J Wang, J Han PloS one 11 (7), e0158655, 2016 | 13 | 2016 |
Skull progenitor cell-driven meningeal lymphatic restoration improves neurocognitive functions in craniosynostosis L Ma, Q Chang, F Pei, M Liu, W Zhang, YK Hong, Y Chai, JF Chen Cell Stem Cell 30 (11), 1472-1485. e7, 2023 | 12 | 2023 |
A snoRNA–tRNA modification network governs codon-biased cellular states M Zhang, K Li, J Bai, R Van Damme, W Zhang, M Alba, BL Stiles, JF Chen, ... Proceedings of the National Academy of Sciences 120 (41), e2312126120, 2023 | 11 | 2023 |
Murine pluripotent stem cells that escape differentiation inside teratomas maintain pluripotency JH Yangli Pei, Liang Yue, Wei Zhang, Jinzhu Xiang, Zhu Ma PeerJ 6 (e4177), eCollection 2018, 2018 | 6* | 2018 |
Recapitulating and reversing human brain ribosomopathy defects via the maladaptive integrated stress response W Zhang, M Zhang, L Ma, S Jariyasakulroj, Q Chang, Z Lin, Z Lu, JF Chen Science Advances 10 (5), eadk1034, 2024 | 3 | 2024 |