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Daniel J. Sharpe
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Rare events and first passage time statistics from the energy landscape
TD Swinburne, D Kannan, DJ Sharpe, DJ Wales
The Journal of Chemical Physics 153 (13), 134115, 2020
222020
Nearly reducible finite Markov chains: Theory and algorithms
DJ Sharpe, DJ Wales
The Journal of Chemical Physics 155 (14), 140901, 2021
212021
Efficient and exact sampling of transition path ensembles on Markovian networks
DJ Sharpe, DJ Wales
The Journal of Chemical Physics 153 (2), 024121, 2020
212020
Identifying mechanistically distinct pathways in kinetic transition networks
DJ Sharpe, DJ Wales
The Journal of Chemical Physics 151 (12), 124101, 2019
182019
Optimal dimensionality reduction of Markov chains using graph transformation
D Kannan, DJ Sharpe, TD Swinburne, DJ Wales
The Journal of Chemical Physics 153 (24), 244108, 2020
162020
Energy Landscapes and Hybridization Pathways for DNA Hexamer Duplexes
S Xiao, DJ Sharpe, D Chakraborty, DJ Wales
The journal of physical chemistry letters 10 (21), 6771-6779, 2019
142019
Numerical analysis of first-passage processes in finite Markov chains exhibiting metastability
DJ Sharpe, DJ Wales
Physical Review E 104 (1), 015301, 2021
132021
Analysing ill-conditioned Markov chains
EJ Woods, D Kannan, DJ Sharpe, TD Swinburne, DJ Wales
Philosophical Transactions of the Royal Society A 381 (2250), 20220245, 2023
92023
Use of Advanced Flexible Modeling Approaches for Survival Extrapolation from Early Follow-up Data in two Nivolumab Trials in Advanced NSCLC with Extended Follow-up
MA Chaudhary, M Edmondson-Jones, G Baio, E Mackay, JR Penrod, ...
Medical Decision Making 43 (1), 91-109, 2023
82023
Graph transformation and shortest paths algorithms for finite Markov chains
DJ Sharpe, DJ Wales
Physical Review E 103 (6), 063306, 2021
72021
Approximating the Shifted Hartree-Exchange-Correlation Potential in Direct Energy Kohn–Sham Theory
DJ Sharpe, M Levy, DJ Tozer
Journal of chemical theory and computation 14 (2), 684-692, 2018
72018
Stochastic paths controlling speed and dissipation
RA Bone, DJ Sharpe, DJ Wales, JR Green
Physical Review E 106 (5), 054151, 2022
32022
Energy Landscapes of Deoxyxylo-and Xylo-Nucleic Acid Octamers
DJ Sharpe, K Röder, DJ Wales
The Journal of Physical Chemistry B 124 (20), 4062-4068, 2020
22020
Stable and scalable computation of state visitation probabilities in finite Markov chains
DJ Sharpe, DJ Wales
The Journal of Chemical Physics 158 (21), 2023
12023
1459P Analysis of long-term efficacy outcomes from the CheckMate 025 (CM 025) trial comparing nivolumab (NIVO) vs everolimus (EVE) based on≥ 7 years (yrs) of follow-up in pre …
B Escudier, RJ Motzer, M Dyer, JR May, F Ejzykowicz, M Kurt, CW Lee, ...
Annals of Oncology 33, S1212, 2022
12022
HTA356 Bridging the Gap between National and EUNETHTA21 HTA Methods. Are Marketing Authorisation Holders Ready for Joint Clinical Assessments?
J Campbell, HR Conesa, D Sharpe, E Turkstra
Value in Health 26 (12), S389, 2023
2023
MSR113 Inferring the Proportion of Durable Responders to Targeted Oncology Therapies in Combination Regimens Using Bayesian Parametric Mixture Survival Models
D Sharpe
Value in Health 26 (12), S414-S415, 2023
2023
MSR13 Formulating Bayesian Poly-Hazard Models for Informed and Clinically Interpretable Lifetime Survival Extrapolations in Advanced Non-Small Cell Lung Cancer (aNSCLC)
D Sharpe, G Yates, L García-Fernández, Y Yuan, A Lee, MA Chaudhary
Value in Health 26 (12), S395, 2023
2023
MSR143 Extending Bayesian Evidence Synthesis to Include Historical Trial Data for Improved Survival Extrapolations from Early Data Cuts in Metastatic Non-Small Cell Lung Cancer …
D Sharpe, G Yates, L García-Fernández, Y Yuan, A Lee, MA Chaudhary
Value in Health 26 (12), S420-S421, 2023
2023
MSR53 Bayesian Parametric Mixture Survival Models in Immuno-Oncology Applications: Leveraging Control Arm Observations to Model Heterogeneous Response in the Experimental Arm
D Sharpe, T De, G Yates, S Baxi, L García-Fernández, ...
Value in Health 26 (6), S286-S287, 2023
2023
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Articles 1–20