| Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients J Hadjadj, N Yatim, L Barnabei, A Corneau, J Boussier, N Smith, H Péré, ... Science 369 (6504), 718-724, 2020 | 3086 | 2020 |
| Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 509 | 2021 |
| X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 372 | 2021 |
| Angiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients DM Smadja, CL Guerin, R Chocron, N Yatim, J Boussier, N Gendron, ... Angiogenesis 23, 611-620, 2020 | 268 | 2020 |
| Efficacy of the Janus kinase 1/2 inhibitor ruxolitinib in the treatment of vasculopathy associated with TMEM173-activating mutations in 3 children ML Frémond, MP Rodero, N Jeremiah, A Belot, E Jeziorski, D Duffy, ... Journal of Allergy and Clinical Immunology 138 (6), 1752-1755, 2016 | 240 | 2016 |
| Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges B Piasecka, D Duffy, A Urrutia, H Quach, E Patin, C Posseme, J Bergstedt, ... Proceedings of the National Academy of Sciences 115 (3), E488-E497, 2018 | 217 | 2018 |
| Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines P Scepanovic, C Alanio, C Hammer, F Hodel, J Bergstedt, E Patin, ... Genome medicine 10, 1-13, 2018 | 163 | 2018 |
| The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 153 | 2022 |
| Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection N Smith, P Goncalves, B Charbit, L Grzelak, M Beretta, C Planchais, ... Nature immunology 22 (11), 1428-1439, 2021 | 146 | 2021 |
| Platelet activation in critically ill COVID-19 patients N Yatim, J Boussier, R Chocron, J Hadjadj, A Philippe, N Gendron, ... Annals of intensive care 11, 1-12, 2021 | 72 | 2021 |
| A monocyte/dendritic cell molecular signature of SARS-CoV-2-related multisystem inflammatory syndrome in children with severe myocarditis C de Cevins, M Luka, N Smith, S Meynier, A Magérus, F Carbone, ... Med 2 (9), 1072-1092. e7, 2021 | 62 | 2021 |
| Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers AL Byrd, M Liu, KE Fujimura, S Lyalina, DR Nagarkar, B Charbit, ... Journal of Experimental Medicine 218 (1), 2021 | 54 | 2021 |
| Smoking changes adaptive immunity with persistent effects V Saint-André, B Charbit, A Biton, V Rouilly, C Possémé, A Bertrand, ... Nature 626 (8000), 827-835, 2024 | 51 | 2024 |
| Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement—a new target for lupus treatment N Smith, MP Rodero, N Bekaddour, V Bondet, YB Ruiz-Blanco, M Harms, ... Science advances 5 (7), eaav9019, 2019 | 46 | 2019 |
| Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus E Clave, IL Araujo, C Alanio, E Patin, J Bergstedt, A Urrutia, ... Science translational medicine 10 (457), eaao2966, 2018 | 45 | 2018 |
| Regulation of the acetylcholine/α7nAChR anti-inflammatory pathway in COVID-19 patients A Courties, J Boussier, J Hadjadj, N Yatim, L Barnabei, H Péré, D Veyer, ... Scientific Reports 11 (1), 11886, 2021 | 44 | 2021 |
| Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity N Smith, C Possémé, V Bondet, J Sugrue, L Townsend, B Charbit, ... Nature Communications 13 (1), 7254, 2022 | 43 | 2022 |
| Type I interferon response and vascular alteration in chilblain‐like lesions during the COVID‐19 outbreak L Frumholtz, JD Bouaziz, M Battistella, J Hadjadj, R Chocron, D Bengoufa, ... British Journal of Dermatology 185 (6), 1176-1185, 2021 | 42 | 2021 |
| Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection N Yatim, J Boussier, P Tetu, N Smith, T Bruel, B Charbit, L Barnabei, ... Science Advances 7 (34), eabg4081, 2021 | 34 | 2021 |
| Severe COVID-19 is associated with hyperactivation of the alternative complement pathway J Boussier, N Yatim, A Marchal, J Hadjadj, B Charbit, C El Sissy, N Carlier, ... Journal of Allergy and Clinical Immunology 149 (2), 550-556. e2, 2022 | 30 | 2022 |
