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Chen Xi Yang
Chen Xi Yang
Verified email at hli.ubc.ca
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ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
JM Leung, CX Yang, A Tam, T Shaipanich, TL Hackett, GK Singhera, ...
European Respiratory Journal 55 (5), 2020
9582020
BMI is associated with FEV1 decline in chronic obstructive pulmonary disease: a meta-analysis of clinical trials
Y Sun, S Milne, JE Jaw, CX Yang, F Xu, X Li, M Obeidat, DD Sin
Respiratory research 20, 1-10, 2019
1062019
COVID-19 and nicotine as a mediator of ACE-2
JM Leung, CX Yang, DD Sin
European Respiratory Journal 55 (6), 2020
1012020
Defective fibrillar collagen organization by fibroblasts contributes to airway remodeling in asthma
LB Mostaço-Guidolin, ET Osei, J Ullah, S Hajimohammadi, M Fouadi, X Li, ...
American journal of respiratory and critical care medicine 200 (4), 431-443, 2019
872019
SARS-CoV-2 receptor ACE2 gene expression and RAAS inhibitors
S Milne, CX Yang, W Timens, Y Bossé, DD Sin
The Lancet Respiratory Medicine 8 (6), e50-e51, 2020
792020
Inhaled corticosteroids downregulate SARS-CoV-2-related genes in COPD: results from a randomised controlled trial
S Milne, X Li, CX Yang, FS Leitao Filho, AIH Cordero, CWT Yang, ...
European Respiratory Journal 58 (1), 2021
472021
Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19
AI Hernández Cordero, X Li, S Milne, CX Yang, Y Bossé, P Joubert, ...
Human genetics 140, 969-979, 2021
392021
Reply to:“Current smoking is not associated with COVID-19”
JM Leung, CX Yang, DD Sin
European Respiratory Journal 55 (6), 2020
312020
Whole blood vs PBMC: compartmental differences in gene expression profiling exemplified in asthma
D He, CX Yang, B Sahin, A Singh, CP Shannon, JP Oliveria, ...
Allergy, Asthma & Clinical Immunology 15, 1-10, 2019
312019
Effect of GST variants on lung function following diesel exhaust and allergen co-exposure in a controlled human crossover study
X Zhang, JA Hirota, C Yang, C Carlsten
Free Radical Biology and Medicine 96, 385-391, 2016
302016
Macrophages with reduced expressions of classical M1 and M2 surface markers in human bronchoalveolar lavage fluid exhibit pro-inflammatory gene signatures
H Takiguchi, CX Yang, CWT Yang, B Sahin, BA Whalen, S Milne, K Akata, ...
Scientific reports 11 (1), 8282, 2021
282021
Occurrence of accelerated epigenetic aging and methylation disruptions in human immunodeficiency virus infection before antiretroviral therapy
CX Yang, E Schon, M Obeidat, MS Kobor, L McEwen, J MacIsaac, D Lin, ...
The Journal of infectious diseases 223 (10), 1681-1689, 2021
232021
Protective effect of club cell secretory protein (CC-16) on COPD risk and progression: a Mendelian randomisation study
S Milne, X Li, AIH Cordero, CX Yang, MH Cho, TH Beaty, I Ruczinski, ...
Thorax 75 (11), 934-943, 2020
212020
Airway aging and methylation disruptions in HIV-associated chronic obstructive pulmonary disease
AI Hernández Cordero, CX Yang, J Yang, S Horvath, T Shaipanich, ...
American Journal of Respiratory and Critical Care Medicine 206 (2), 150-160, 2022
182022
Novel blood-based transcriptional biomarker panels predict the late-phase asthmatic response
A Singh, CP Shannon, YW Kim, CX Yang, R Balshaw, GV Cohen Freue, ...
American journal of respiratory and critical care medicine 197 (4), 450-462, 2018
182018
Pulmonary function and blood DNA methylation: a multiancestry epigenome-wide association meta-analysis
M Lee, T Huan, DL McCartney, G Chittoor, M de Vries, L Lahousse, ...
American Journal of Respiratory and Critical Care Medicine 206 (3), 321-336, 2022
172022
DNA methylation is associated with airflow obstruction in patients living with HIV
AIH Cordero, CX Yang, M Obeidat, J Yang, J MacIsaac, L McEwen, D Lin, ...
Thorax 76 (5), 448-455, 2021
162021
Widespread sexual dimorphism in the transcriptome of human airway epithelium in response to smoking
CX Yang, H Shi, I Ding, S Milne, AI Hernandez Cordero, CWT Yang, ...
Scientific reports 9 (1), 17600, 2019
152019
A single-cell atlas of small airway disease in chronic obstructive pulmonary disease: a cross-sectional study
S Booth, A Hsieh, L Mostaco-Guidolin, HK Koo, K Wu, F Aminazadeh, ...
American Journal of Respiratory and Critical Care Medicine 208 (4), 472-486, 2023
142023
Abundance of non-polarized lung macrophages with poor phagocytic function in chronic obstructive pulmonary disease (COPD)
K Akata, K Yamasaki, FS Leitao Filho, CX Yang, H Takiguchi, B Sahin, ...
Biomedicines 8 (10), 398, 2020
142020
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