mTOR signaling: at the crossroads of plasticity, memory and disease CA Hoeffer, E Klann Trends in neurosciences 33 (2), 67-75, 2010 | 1262 | 2010 |
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring GB Choi, YS Yim, H Wong, S Kim, H Kim, SV Kim, CA Hoeffer, DR Littman, ... Science 351 (6276), 933-939, 2016 | 1054 | 2016 |
Dysregulation of mTOR signaling in fragile X syndrome A Sharma, CA Hoeffer, Y Takayasu, T Miyawaki, SM McBride, E Klann, ... Journal of neuroscience 30 (2), 694-702, 2010 | 619 | 2010 |
Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease T Ma, CA Hoeffer, E Capetillo-Zarate, F Yu, H Wong, MT Lin, D Tampellini, ... PloS one 5 (9), e12845, 2010 | 280 | 2010 |
Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior CA Hoeffer, W Tang, H Wong, A Santillan, RJ Patterson, LA Martinez, ... Neuron 60 (5), 832-845, 2008 | 241 | 2008 |
AP-1 functions upstream of CREB to control synaptic plasticity in Drosophila S Sanyal, DJ Sandstrom, CA Hoeffer, M Ramaswami Nature 416 (6883), 870-874, 2002 | 217 | 2002 |
Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome CA Hoeffer, E Sanchez, RJ Hagerman, Y Mu, DV Nguyen, H Wong, ... Genes, Brain and Behavior 11 (3), 332-341, 2012 | 212 | 2012 |
Nicotine reverses hypofrontality in animal models of addiction and schizophrenia F Koukouli, M Rooy, D Tziotis, KA Sailor, HC O'Neill, J Levenga, M Witte, ... Nature medicine 23 (3), 347-354, 2017 | 205 | 2017 |
Synaptic plasticity deficits and mild memory impairments in mouse models of chronic granulomatous disease KT Kishida, CA Hoeffer, D Hu, M Pao, SM Holland, E Klann Molecular and cellular biology 26 (15), 5908-5920, 2006 | 179 | 2006 |
Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission T Karayannis, E Au, JC Patel, I Kruglikov, S Markx, R Delorme, D Héron, ... Nature 511 (7508), 236-240, 2014 | 177 | 2014 |
Amyloid β-induced impairments in hippocampal synaptic plasticity are rescued by decreasing mitochondrial superoxide T Ma, CA Hoeffer, H Wong, CA Massaad, P Zhou, C Iadecola, MP Murphy, ... Journal of Neuroscience 31 (15), 5589-5595, 2011 | 173 | 2011 |
Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity MD Antion, M Merhav, CA Hoeffer, G Reis, SC Kozma, G Thomas, ... Learning & Memory 15 (1), 29-38, 2008 | 165 | 2008 |
Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome A Suvrathan, CA Hoeffer, H Wong, E Klann, S Chattarji Proceedings of the National Academy of Sciences 107 (25), 11591-11596, 2010 | 161 | 2010 |
mGluR-dependent long-term depression is associated with increased phosphorylation of S6 and synthesis of elongation factor 1A but remains expressed in S6K-deficient mice MD Antion, L Hou, H Wong, CA Hoeffer, E Klann Molecular and cellular biology 28 (9), 2996-3007, 2008 | 137 | 2008 |
Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments J Levenga, P Krishnamurthy, H Rajamohamedsait, H Wong, TF Franke, ... Acta neuropathologica communications 1, 1-14, 2013 | 127 | 2013 |
Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation CA Hoeffer, KK Cowansage, EC Arnold, JL Banko, NJ Moerke, ... Proceedings of the National Academy of Sciences 108 (8), 3383-3388, 2011 | 127 | 2011 |
Maternal IL-17A in autism H Wong, C Hoeffer Experimental neurology 299, 228-240, 2018 | 120 | 2018 |
The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling CA Hoeffer, A Dey, N Sachan, H Wong, RJ Patterson, JM Shelton, ... Journal of Neuroscience 27 (48), 13161-13172, 2007 | 112 | 2007 |
AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity J Levenga, H Wong, RA Milstead, BN Keller, LE LaPlante, CA Hoeffer Elife 6, e30640, 2017 | 98 | 2017 |
Haloperidol regulates the state of phosphorylation of ribosomal protein S6 via activation of PKA and phosphorylation of DARPP-32 E Valjent, J Bertran-Gonzalez, H Bowling, S Lopez, E Santini, ... Neuropsychopharmacology 36 (12), 2561-2570, 2011 | 79 | 2011 |