| Neuronal Ca 2+ stores: activation and function PB Simpson, RAJ Challiss, SR Nahorski Trends in neurosciences 18 (7), 299-306, 1995 | 376 | 1995 |
| α4β3δ GABAAReceptors Characterized by Fluorescence Resonance Energy Transfer-derived Measurements of Membrane Potential CE Adkins, GV Pillai, J Kerby, TP Bonnert, C Haldon, RM McKernan, ... Journal of Biological Chemistry 276 (42), 38934-38939, 2001 | 223 | 2001 |
| Neurotransmitter-and growth factor-induced cAMP response element binding protein phosphorylation in glial cell progenitors: role of calcium ions, protein kinase C, and mitogen … M Pende, TL Fisher, PB Simpson, JT Russell, J Blenis, V Gallo Journal of Neuroscience 17 (4), 1291-1301, 1997 | 207 | 1997 |
| High density distribution of endoplasmic reticulum proteins and mitochondria at specialized Ca2+ release sites in oligodendrocyte processes PB Simpson, S Mehotra, GD Lange, JT Russell Journal of Biological Chemistry 272 (36), 22654-22661, 1997 | 183 | 1997 |
| Mitochondria support inositol 1, 4, 5-trisphosphate-mediated Ca2+ waves in cultured oligodendrocytes PB Simpson, JT Russell Journal of Biological Chemistry 271 (52), 33493-33501, 1996 | 165 | 1996 |
| Role of mitochondrial Ca 2+ regulation in neuronal and glial cell signalling PB Simpson, JT Russell Brain research reviews 26 (1), 72-81, 1998 | 147 | 1998 |
| Intracellular signals and cytoskeletal elements involved in oligodendrocyte progenitor migration PB Simpson, RC Armstrong Glia 26 (1), 22-35, 1999 | 144 | 1999 |
| Retinoic acid-evoked differentiation of neuroblastoma cells predominates over growth factor stimulation: an automated image capture and quantitation approach to neuritogenesis PB Simpson, JI Bacha, EL Palfreyman, AJ Woollacott, RM McKernan, ... Analytical biochemistry 298 (2), 163-169, 2001 | 98 | 2001 |
| Comparison of type 2 inositol 1, 4, 5-trisphosphate receptor distribution and subcellular Ca2 release sites that support Ca2 waves in cultured astrocytes CA Sheppard, PB Simpson, AH Sharp, FC Nucifora, CA Ross, GD Lange, ... J Neurochem 68, 2317-2327, 1997 | 96 | 1997 |
| Involvement of Intracellular Stores in the Ca2+ Responses to N‐Methyl‐D‐Aspartate and Depolarization in Cerebellar Granule Cells PB Simpson, RA Challiss, SR Nahorski Journal of neurochemistry 61 (2), 760-763, 1993 | 87 | 1993 |
| Role of sarcoplasmic/endoplasmic-reticulum Ca2+-ATPases in mediating Ca2+ waves and local Ca2+-release microdomains in cultured glia PB SIMPSON, JT RUSSELL Biochemical Journal 325 (1), 239-247, 1997 | 83 | 1997 |
| Specialized distributions of mitochondria and endoplasmic reticulum proteins define Ca2+ wave amplification sites in cultured astrocytes PB Simpson, S Mehotra, D Langley, CA Sheppard Journal of neuroscience research 52 (6), 672-683, 1998 | 70 | 1998 |
| Agonist‐Evoked Ca2+ Mobilization from Stores Expressing Inositol 1, 4, 5‐Trisphosphate Receptors and Ryanodine Receptors in Cerebellar Granule Neurones PB Simpson, SR Nahorski, RA Challiss Journal of neurochemistry 67 (1), 364-373, 1996 | 69 | 1996 |
| Mitochondrial Ca2+ uptake and release influence metabotropic and ionotropic cytosolic Ca2+ responses in rat oligodendrocyte progenitors PB Simpson, JT Russell The Journal of physiology 508 (Pt 2), 413, 1998 | 63 | 1998 |
| Divalent cation entry in cultured rat cerebellar granule cells measured using Mn2+ quench of fura 2 fluorescence PB Simpson, RAJ Challiss, SR Nahorski European Journal of Neuroscience 7 (5), 831-840, 1995 | 59 | 1995 |
| Salicylidene salicylhydrazide, a selective inhibitor of β1‐containing GABAA receptors SA Thompson, L Wheat, NA Brown, PB Wingrove, GV Pillai, PJ Whiting, ... British journal of pharmacology 142 (1), 97-106, 2004 | 53 | 2004 |
| Characterization of ryanodine receptors in oligodendrocytes, type 2 astrocytes, and O‐2A progenitors PB Simpson, LA Holtzclaw, DB Langley, JT Russell Journal of neuroscience research 52 (4), 468-482, 1998 | 52 | 1998 |
| The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing CD Jones, DM Andrews, AJ Barker, K Blades, P Daunt, S East, C Geh, ... Bioorganic & medicinal chemistry letters 18 (24), 6369-6373, 2008 | 51 | 2008 |
| Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and … N Ingram, LE McVeigh, RH Abou-Saleh, J Maynard, SA Peyman, ... Theranostics 10 (24), 10973, 2020 | 50 | 2020 |
| Organ-on-a-chip technology: turning its potential for clinical benefit into reality M Haddrick, PB Simpson Drug discovery today 24 (5), 1217-1223, 2019 | 50 | 2019 |
John ChallissProfessor of Molecular & Cellular Pharmacology, University of LeicesterVerified email at leicester.ac.uk
