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Christopher Jacobs
Christopher Jacobs
Beth Israel Deaconess Medical Center
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity
HC Roh, LTY Tsai, M Shao, D Tenen, Y Shen, M Kumari, A Lyubetskaya, ...
Cell metabolism 27 (5), 1121-1137. e5, 2018
2172018
Obesity-linked PPARγ S273 phosphorylation promotes insulin resistance through Growth Differentiation Factor 3
JA Hall, D Ramachandran, HC Roh, JR DiSpirito, T Belchior, PJH Zushin, ...
Cell Metabolism 32 (4), 665-675. e6, 2020
712020
IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis
S Yan, M Kumari, H Xiao, C Jacobs, S Kochumon, M Jedrychowski, ...
The Journal of Clinical Investigation, 2021
512021
Targeted analysis of glycomics liquid chromatography/mass spectrometry data
JM Dreyfuss, C Jacobs, Y Gindin, G Benson, GO Staples, J Zaia
Analytical and bioanalytical chemistry 399 (2), 727-735, 2011
232011
Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling
HC Roh, M Kumari, S Taleb, D Tenen, C Jacobs, A Lyubetskaya, LTY Tsai, ...
Molecular metabolism 42, 101086, 2020
222020
NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor
A Mendoza, I Astapova, H Shimizu, MR Gallop, L Al-Sowaimel, ...
Proceedings of the National Academy of Sciences 114 (40), E8458-E8467, 2017
212017
Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies
S Chandani, C Jacobs, EL Loechler
Journal of nucleic acids 2010, 2010
172010
Upon accounting for the impact of isoenzyme loss, gene deletion costs anticorrelate with their evolutionary rates
C Jacobs, L Lambourne, Y Xia, D Segrè
PloS one 12 (1), e0170164, 2017
152017
Organization principles in genetic interaction networks
C Jacobs, D Segre
Evolutionary systems biology, 53-78, 2012
92012
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