| MolProbity: More and better reference data for improved all‐atom structure validation CJ Williams, JJ Headd, NW Moriarty, MG Prisant, LL Videau, LN Deis, ... Protein Science 27 (1), 293-315, 2018 | 2911 | 2018 |
| ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ... Methods in enzymology 487, 545-574, 2011 | 1942 | 2011 |
| Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 572 | 2020 |
| Macromolecular modeling and design in Rosetta: new methods and frameworks JK Leman, BD Weitzner, SM Lewis, R Bonneau, ... Preprints, 2019 | 572* | 2019 |
| Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface SM Lewis, X Wu, A Pustilnik, A Sereno, F Huang, HL Rick, G Guntas, ... Nature biotechnology 32 (2), 191-198, 2014 | 284 | 2014 |
| Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates G Kleiger, A Saha, S Lewis, B Kuhlman, RJ Deshaies Cell 139 (5), 957-968, 2009 | 211 | 2009 |
| Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3 HB Kamadurai, Y Qiu, A Deng, JS Harrison, C MacDonald, M Actis, ... Elife 2, e00828, 2013 | 189 | 2013 |
| Essential role for ubiquitin-ubiquitin-conjugating enzyme interaction in ubiquitin discharge from Cdc34 to substrate A Saha, S Lewis, G Kleiger, B Kuhlman, RJ Deshaies Molecular cell 42 (1), 75-83, 2011 | 127 | 2011 |
| Molprobity's ultimate rotamer‐library distributions for model validation BJ Hintze, SM Lewis, JS Richardson, DC Richardson Proteins: Structure, Function, and Bioinformatics 84 (9), 1177-1189, 2016 | 114 | 2016 |
| Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function R Baker, SM Lewis, AT Sasaki, EM Wilkerson, JW Locasale, LC Cantley, ... Nature structural & molecular biology 20 (1), 46-52, 2013 | 100 | 2013 |
| A biosensor generated via high-throughput screening quantifies cell edge Src dynamics A Gulyani, E Vitriol, R Allen, J Wu, D Gremyachinskiy, S Lewis, B Dewar, ... Nature chemical biology 7 (7), 437-444, 2011 | 90 | 2011 |
| Supertertiary structure of the MAGUK core from PSD-95 J Zhang, SM Lewis, B Kuhlman, AL Lee Structure 21 (3), 402-413, 2013 | 76 | 2013 |
| Anchored design of protein-protein interfaces SM Lewis, BA Kuhlman PloS one 6 (6), e20872, 2011 | 76 | 2011 |
| Prediction of protein mutational free energy: benchmark and sampling improvements increase classification accuracy B Frenz, SM Lewis, I King, F DiMaio, H Park, Y Song Frontiers in bioengineering and biotechnology, 1175, 2020 | 67 | 2020 |
| Fab-based bispecific antibody formats with robust biophysical properties and biological activity X Wu, AJ Sereno, F Huang, SM Lewis, RL Lieu, C Weldon, C Torres, ... MAbs 7 (3), 470-482, 2015 | 67 | 2015 |
| Photomodulated PPV emission in a photochromic polymer film SM Lewis, EJ Harbron The Journal of Physical Chemistry C 111 (11), 4425-4430, 2007 | 37 | 2007 |
| Better together: Elements of successful scientific software development in a distributed collaborative community J Koehler Leman, BD Weitzner, PD Renfrew, SM Lewis, R Moretti, ... PLOS Computational Biology 16 (5), e1007507, 2020 | 34 | 2020 |
| Engineering a genetically encoded competitive inhibitor of the KEAP1–NRF2 interaction via structure-based design and phage display G Guntas, SM Lewis, KM Mulvaney, EW Cloer, A Tripathy, TR Lane, ... Protein Engineering, Design & Selection 29 (1), 1-9, 2016 | 27 | 2016 |
| Ubiquitin-conjugating enzyme Cdc34 and ubiquitin ligase Skp1-cullin-F-box ligase (SCF) interact through multiple conformations D Sandoval, S Hill, A Ziemba, S Lewis, B Kuhlman, G Kleiger Journal of Biological Chemistry 290 (2), 1106-1118, 2015 | 23 | 2015 |
| Nerve agent hydrolysis activity designed into a human drug metabolism enzyme. H AC, O TC, C RA, W M, E JS, L SM, E CC, T L, C CL, K SA, Cashman JR, ... PLoS One 6 (3), 2011 | 18 | 2011 |
