Paul J Fletcher
Paul J Fletcher
Centre for Addiction and Mental Health
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Reinstatement of alcohol-seeking by priming injections of alcohol and exposure to stress in rats
AD Le, B Quan, W Juzytch, PJ Fletcher, N Joharchi, Y Shaham
Psychopharmacology 135, 169-174, 1998
Antidepressant-like effects of medial prefrontal cortex deep brain stimulation in rats
C Hamani, M Diwan, CE Macedo, ML Brandão, J Shumake, ...
Biological psychiatry 67 (2), 117-124, 2010
Differential effects of the 5-HT2A receptor antagonist M100, 907 and the 5-HT2C receptor antagonist SB242, 084 on cocaine-induced locomotor activity, cocaine self …
PJ Fletcher, AJ Grottick, GA Higgins
Neuropsychopharmacology 27 (4), 576-586, 2002
Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor
FJS Lee, L Pei, A Moszczynska, B Vukusic, PJ Fletcher, F Liu
The EMBO journal 26 (8), 2127-2136, 2007
Cannabidiol, a non‐psychotropic component of cannabis, attenuates vomiting and nausea‐like behaviour via indirect agonism of 5‐HT1A somatodendritic …
EM Rock, D Bolognini, CL Limebeer, MG Cascio, S Anavi‐Goffer, ...
British journal of pharmacology 165 (8), 2620-2634, 2012
The amphetamine-induced sensitized state as a model of schizophrenia
RE Featherstone, S Kapur, PJ Fletcher
Progress in Neuro-Psychopharmacology and Biological Psychiatry 31 (8), 1556-1571, 2007
Studies to investigate the role of 5-HT2C receptors on cocaine-and food-maintained behavior
AJ Grottick, PJ Fletcher, GA Higgins
Journal of Pharmacology and Experimental therapeutics 295 (3), 1183-1191, 2000
Opposing effects of 5-HT2A and 5-HT2C receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test
PJ Fletcher, M Tampakeras, J Sinyard, GA Higgins
Psychopharmacology 195, 223-234, 2007
Dissociation between in vivo occupancy and functional antagonism of dopamine D2 receptors: comparing aripiprazole to other antipsychotics in animal models
S Natesan, GE Reckless, JN Nobrega, PJ Fletcher, S Kapur
Neuropsychopharmacology 31 (9), 1854-1863, 2006
The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: increased high affinity state following amphetamine and in schizophrenia
ML Perreault, A Hasbi, M Alijaniaram, T Fan, G Varghese, PJ Fletcher, ...
Journal of Biological Chemistry 285 (47), 36625-36634, 2010
Abnormalities in brain structure and behavior in GSK-3alpha mutant mice
O Kaidanovich-Beilin, TV Lipina, K Takao, M Van Eede, S Hattori, ...
Molecular brain 2, 1-23, 2009
Disruption of dopamine D1 receptor gene expression attenuates alcohol-seeking behavior
M El-Ghundi, SR George, J Drago, PJ Fletcher, T Fan, T Nguyen, C Liu, ...
European journal of pharmacology 353 (2-3), 149-158, 1998
The 5-HT2A receptor antagonist M100,907 attenuates motor and 'impulsive-type' behaviours produced by NMDA receptor antagonism
GA Higgins, M Enderlin, M Haman, PJ Fletcher
Psychopharmacology 170, 309-319, 2003
Serotonin and drug reward: focus on 5-HT2C receptors
GA Higgins, PJ Fletcher
European journal of pharmacology 480 (1-3), 151-162, 2003
Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects
L Pei, S Li, M Wang, M Diwan, H Anisman, PJ Fletcher, JN Nobrega, F Liu
Nature medicine 16 (12), 1393-1395, 2010
Spatial learning deficit in dopamine D1 receptor knockout mice
M El-Ghundi, PJ Fletcher, J Drago, DR Sibley, BF O'Dowd, SR George
European journal of pharmacology 383 (2), 95-106, 1999
Sensitization to amphetamine, but not PCP, impairs attentional set shifting: reversal by a D1 receptor agonist injected into the medial prefrontal cortex
PJ Fletcher, CC Tenn, Z Rizos, V Lovic, S Kapur
Psychopharmacology 183, 190-200, 2005
Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1‐targeted mice
EJ Young, T Lipina, E Tam, A Mandel, SJ Clapcote, AR Bechard, ...
Genes, Brain and Behavior 7 (2), 224-234, 2008
The nicotinic acetylcholine receptor α5 subunit plays a key role in attention circuitry and accuracy
CDC Bailey, M De Biasi, PJ Fletcher, EK Lambe
Journal of neuroscience 30 (27), 9241-9252, 2010
Insulin resistance and secretion in vivo: effects of different antipsychotics in an animal model
AF Chintoh, SW Mann, L Lam, A Giacca, P Fletcher, J Nobrega, ...
Schizophrenia research 108 (1-3), 127-133, 2009
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