| Neuronal network activity controls microglial process surveillance in awake mice via norepinephrine signaling YU Liu, Y Ying, Y Li, UB Eyo, T Chen, J Zheng, AD Umpierre, J Zhu, ... Nature neuroscience 22 (11), 1771-1781, 2019 | 284 | 2019 |
| Alzheimer’s risk factors age, APOE genotype, and sex drive distinct molecular pathways N Zhao, Y Ren, Y Yamazaki, W Qiao, F Li, LM Felton, ... Neuron 106 (5), 727-742. e6, 2020 | 176 | 2020 |
| APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid N Zhao, ON Attrebi, Y Ren, W Qiao, B Sonustun, YA Martens, ... Science translational medicine 12 (529), eaay1809, 2020 | 110 | 2020 |
| Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice MH Yi, YU Liu, K Liu, T Chen, DB Bosco, J Zheng, M Xie, L Zhou, W Qu, ... Brain, behavior, and immunity 92, 78-89, 2021 | 84 | 2021 |
| The complement C3‐C3aR pathway mediates microglia–astrocyte interaction following status epilepticus Y Wei, T Chen, DB Bosco, M Xie, J Zheng, A Dheer, Y Ying, Q Wu, ... Glia 69 (5), 1155-1169, 2021 | 67 | 2021 |
| Brain cancer induces systemic immunosuppression through release of non-steroid soluble mediators K Ayasoufi, CK Pfaller, L Evgin, RH Khadka, ZP Tritz, EN Goddery, ... Brain 143 (12), 3629-3652, 2020 | 47 | 2020 |
| Optogenetic activation of spinal microglia triggers chronic pain in mice MH Yi, YU Liu, AD Umpierre, T Chen, Y Ying, J Zheng, A Dheer, ... PLoS biology 19 (3), e3001154, 2021 | 45 | 2021 |
| The GluN2A subunit regulates neuronal NMDA receptor-induced microglia-neuron physical interactions UB Eyo, A Bispo, J Liu, S Sabu, R Wu, VL DiBona, J Zheng, M Murugan, ... Scientific reports 8 (1), 828, 2018 | 44 | 2018 |
| RNAseq analysis of hippocampal microglia after kainic acid-induced seizures DB Bosco, J Zheng, Z Xu, J Peng, UB Eyo, K Tang, C Yan, J Huang, ... Molecular brain 11, 1-13, 2018 | 41 | 2018 |
| Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia N Zhao, W Qiao, F Li, Y Ren, J Zheng, YA Martens, X Wang, L Li, CC Liu, ... Journal of Experimental Medicine 219 (12), e20212479, 2022 | 27 | 2022 |
| The voltage-gated proton channel Hv1 promotes microglia-astrocyte communication and neuropathic pain after peripheral nerve injury J Peng, MH Yi, H Jeong, PP McEwan, J Zheng, G Wu, S Ganatra, Y Ren, ... Molecular brain 14, 1-18, 2021 | 23 | 2021 |
| The voltage-gated proton channel Hv1 contributes to neuronal injury and motor deficits in a mouse model of spinal cord injury M Murugan, J Zheng, G Wu, R Mogilevsky, X Zheng, P Hu, J Wu, LJ Wu Molecular brain 13, 1-13, 2020 | 22 | 2020 |
| Microglial voltage-gated proton channel Hv1 in spinal cord injury J Zheng, M Murugan, L Wang, LJ Wu Neural Regeneration Research 17 (6), 1183-1189, 2022 | 9 | 2022 |
| Microglia enhance post-anesthesia neuronal activity by shielding inhibitory synapses K Haruwaka, Y Ying, Y Liang, AD Umpierre, MH Yi, V Kremen, T Chen, ... Nature Neuroscience, 1-13, 2024 | 8 | 2024 |
| VEGF-A in serum protects against memory impairment in APP/PS1 transgenic mice by blocking neutrophil infiltration F Qi, Z Zuo, K Hu, R Wang, T Wu, H Liu, J Tang, Q Wang, Y Xie, L Tan, ... Molecular Psychiatry 28 (10), 4374-4389, 2023 | 5 | 2023 |
| Microglial P2Y6 calcium signaling promotes phagocytosis and shapes neuroimmune responses in epileptogenesis AD Umpierre, B Li, K Ayasoufi, WL Simon, S Zhao, M Xie, G Thyen, B Hur, ... Neuron, 2024 | 4 | 2024 |
| Brain resident memory T cells rapidly expand and initiate neuroinflammatory responses following CNS viral infection K Ayasoufi, DM Wolf, SL Namen, F Jin, ZP Tritz, CK Pfaller, J Zheng, ... Brain, Behavior, and Immunity 112, 51-76, 2023 | 4 | 2023 |
| TREM2 mediates MHCII-associated CD4+ T cell response against gliomas J Zheng, L Wang, S Zhao, W Zhang, Y Chang, A Dheer, S Gao, S Xu, ... bioRxiv, 2023 | 4 | 2023 |
| Discrete class I molecules on brain endothelium differentially regulate neuropathology in experimental cerebral malaria CE Fain, J Zheng, F Jin, K Ayasoufi, Y Wu, MT Lilley, AR Dropik, DM Wolf, ... Brain 147 (2), 566-589, 2024 | 3 | 2024 |
| Chemogenetic approaches reveal dual functions of microglia in seizures A Dheer, DB Bosco, J Zheng, L Wang, S Zhao, K Haruwaka, MH Yi, ... Brain, behavior, and immunity 115, 406-418, 2024 | 3 | 2024 |
Long-Jun WuProfessor of Neurology and Neuroscience, Mayo ClinicVerified email at mayo.edu
