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Than Hein
Than Hein
Singapore General Hospital
Verified email at singhealth.com.sg
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Cited by
Year
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
KP Ng, AM Hillmer, CTH Chuah, WC Juan, TK Ko, ASM Teo, ...
Nature medicine 18 (4), 521-528, 2012
6642012
Combining the allosteric inhibitor asciminib with ponatinib suppresses emergence of and restores efficacy against highly resistant BCR-ABL1 mutants
CA Eide, MS Zabriskie, SLS Stevens, O Antelope, NA Vellore, H Than, ...
Cancer Cell 36 (4), 431-443. e5, 2019
1652019
Genomic landscape of neutrophilic leukemias of ambiguous diagnosis
H Zhang, B Wilmot, D Bottomly, KHT Dao, E Stevens, CA Eide, V Khanna, ...
Blood, The Journal of the American Society of Hematology 134 (11), 867-879, 2019
712019
First experiences with the use of rivaroxaban in the treatment of heparin-induced thrombocytopenia
HJ Ng, H Than, ECY Teo
Thrombosis research 135 (1), 205-207, 2015
482015
Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration
W Xiang, JK Cheong, SH Ang, B Teo, P Xu, K Asari, WT Sun, H Than, ...
Oncotarget 6 (32), 33769, 2015
432015
SIRT5 is a druggable metabolic vulnerability in acute myeloid leukemia
D Yan, A Franzini, AD Pomicter, BJ Halverson, O Antelope, CC Mason, ...
Blood cancer discovery 2 (3), 266, 2021
412021
The transcriptome of CMML monocytes is highly inflammatory and reflects leukemia-specific and age-related alterations
A Franzini, AD Pomicter, D Yan, JS Khorashad, SK Tantravahi, H Than, ...
Blood advances 3 (20), 2949-2961, 2019
332019
Nuclear–cytoplasmic transport is a therapeutic target in myelofibrosis
D Yan, AD Pomicter, S Tantravahi, CC Mason, AV Senina, JM Ahmann, ...
Clinical Cancer Research 25 (7), 2323-2335, 2019
322019
Lysosome inhibition by mefloquine preferentially enhances the cytotoxic effects of tyrosine kinase inhibitors in blast phase chronic myeloid leukemia
HL Yi, H Than, C Sng, MA Cheong, C Chuah, W Xiang
Translational oncology 12 (9), 1221-1228, 2019
182019
Rivaroxaban for heparin-induced thrombocytopenia: adding to the evidence
SY Ong, YA Chin, H Than, CW Tan, ES Yap, WH Wong, HJ Ng
Annals of hematology 96 (3), 525-527, 2017
172017
SRSF1 mediates cytokine-induced impaired imatinib sensitivity in chronic myeloid leukemia
JR Sinnakannu, KL Lee, S Cheng, J Li, M Yu, SP Tan, CCH Ong, H Li, ...
Leukemia 34 (7), 1787-1798, 2020
152020
The EUTOS score is highly predictive for clinical outcome and survival in Asian patients with early chronic phase chronic myeloid leukemia treated with imatinib
H Than, L Kuan, CH Seow, W Li, JC Allen Jr, C Chuah
Blood, The Journal of the American Society of Hematology 120 (21), 3758-3758, 2012
122012
Coordinated inhibition of nuclear export and Bcr-Abl1 selectively targets chronic myeloid leukemia stem cells
H Than, AD Pomicter, D Yan, LP Beaver, AM Eiring, WL Heaton, A Senina, ...
Leukemia 34 (6), 1679-1683, 2020
92020
BIM deletion polymorphism profiling complements prognostic values of risk scores in imatinib-treated Asian chronic myeloid leukemia patients
H Than, WK Lye, C Sng, JC Allen Jr, ST Ong, C Chuah
Leukemia & lymphoma 60 (1), 234-237, 2019
82019
A comprehensive study of current haemophilia care and outcomes in Singapore
HJ Ng, J Lam, PL Koh, L Ho, CY Lim, M Akhbar Ali, D Mya, H Than, LP Ho, ...
Haemophilia 21 (5), e428-31, 2015
82015
Combining the allosteric ABL1 inhibitor asciminib (ABL001) with ponatinib suppresses emergence of and restores efficacy against highly resistant BCR-ABL1 compound mutants
CA Eide, MS Zabriskie, SL Savage, O Antelope, NA Vellore, H Than, ...
Blood 134, 188, 2019
52019
Ongoing clonal evolution in chronic myelomonocytic leukemia on hypomethylating agents: a computational perspective
H Than, Y Qiao, X Huang, D Yan, JS Khorashad, AD Pomicter, ...
Leukemia 32 (9), 2049-2054, 2018
52018
Rapid conversion of chronic myeloid leukemia to chronic myelomonocytic leukemia in a patient on imatinib therapy
JS Khorashad, SK Tantravahi, D Yan, CC Mason, Y Qiao, AM Eiring, ...
Leukemia 30 (11), 2275-2279, 2016
32016
SIRT5 as a therapeutic target in acute myeloid leukemia
D Yan, AD Pomicter, WL Heaton, CC Mason, J Ahmann, A Senina, ...
Blood 132, 907, 2018
22018
Genetic profiling augments prognostic value of the EUTOS long-term survival score for disease-specific mortality in imatinib-treated asian chronic myeloid leukaemia patients
H Than, WK Lye, CH Seow, CN Sng, JC Allen Jr, C Chuah
Blood 128 (22), 3077, 2016
22016
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