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Viktor T. Lemgart, PhD
Viktor T. Lemgart, PhD
Senior Scientist, Sanofi
Verified email at sanofi.com
Title
Cited by
Cited by
Year
Identification of preexisting adaptive immunity to Cas9 proteins in humans
CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart, ...
Nature medicine 25 (2), 249-254, 2019
9322019
Highly efficient and marker-free genome editing of human pluripotent stem cells by CRISPR-Cas9 RNP and AAV6 donor-mediated homologous recombination
RM Martin, K Ikeda, MK Cromer, N Uchida, T Nishimura, R Romano, ...
Cell stem cell 24 (5), 821-828. e5, 2019
1652019
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells
MK Cromer, J Camarena, RM Martin, BJ Lesch, CA Vakulskas, NM Bode, ...
Nature medicine 27 (4), 677-687, 2021
612021
SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells
Y Hara, VT Lemgart, N Halland, K Mahdaviani, JA Ribeil, S Lessard, ...
Blood Advances 7 (11), 2317-2323, 2023
12023
LIPID NANOPARTICLES AND IONIZABLE CATIONIC LIPIDS, AND METHODS OF SYNTHESIS AND USE THEREOF
M Ali, AW Boesch, DC Drummond, W Kuhlman, V Lemgart, U Nielsen
WO Patent WO/2023/240,156, 2023
2023
Genomic discovery and functional validation of MRP1 as a novel fetal hemoglobin modulator and potential therapeutic target in sickle cell disease
Y Hara, E Kawabata, V Lemgart, P Bronson, A Hicks, R Peters, ...
2023
Reprogramming Immune Cells in situ: A Targeted LNP Delivery Technology Utilizing IVT mRNA
VT Lemgart
DTU Health Technology, 2023
2023
Inhibition of MRP1 Induces Fetal Hemoglobin through NRF2 Activation to Protect Human Erythroid Cells from Sickling
Y Hara, E Kawabata, VT Lemgart, PG Bronson, A Hicks, ...
Blood 140 (Supplement 1), 952-953, 2022
2022
Targeting beta-Globin Gene into alpha-Globin Locus in Human Hematopoietic Stem and Progenitor Cells
MK Cromer, J Camarena, RM Martin, BJ Lesch, VT Lemgart, RO Bak, ...
MOLECULAR THERAPY 27 (4), 400-400, 2019
2019
2019 Identification of preexisting adaptive immunity to Cas9 proteins in humans
CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart
Nat. Med 25, 249, 0
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