Amyloid-β peptides disrupt interactions between VAMP-2 and SNAP-25 in neuronal cells as determined by FRET/FLIM N Sharda, T Pengo, Z Wang, KK Kandimalla Journal of Alzheimer's Disease 77 (1), 423-435, 2020 | 16 | 2020 |
Distinct uptake kinetics of Alzheimer disease amyloid-β 40 and 42 at the blood-brain barrier endothelium N Sharda, KM Ahlschwede, GL Curran, VJ Lowe, KK Kandimalla Journal of Pharmacology and Experimental Therapeutics 376 (3), 482-490, 2021 | 12 | 2021 |
Age-dependent changes in the plasma and brain pharmacokinetics of amyloid-β peptides and insulin AL Zhou, N Sharda, VV Sarma, KM Ahlschwede, GL Curran, X Tang, ... Journal of Alzheimer's Disease 85 (3), 1031-1044, 2022 | 8 | 2022 |
Semimechanistic population pharmacokinetic modeling to investigate amyloid beta trafficking and accumulation at the BBB endothelium Z Wang, N Sharda, GL Curran, L Li, VJ Lowe, KK Kandimalla Molecular pharmaceutics 18 (11), 4148-4161, 2021 | 5 | 2021 |
Pharmacokinetics of 40 kDa Polyethylene glycol (PEG) in mice, rats, cynomolgus monkeys and predicted pharmacokinetics in humans N Sharda, P Khandelwal, L Zhang, J Caceres-Cortes, P Marathe, ... European Journal of Pharmaceutical Sciences 165, 105928, 2021 | 3 | 2021 |
Blood‐brain barrier insulin resistance decreases insulin uptake and increases amyloid beta uptake in Alzheimer's disease brain: Developing topics AL Zhou, SK Swaminathan, CC Gali, TJ Bruinsma, GL Curran, VV Sarma, ... Alzheimer's & Dementia 16, e047353, 2020 | 3 | 2020 |
Amyloid-beta peptides 40 and 42 employ distinct molecular pathways for cell entry and intracellular transit at the BBB endothelium Z Wang, N Sharda, RS Omtri, L Li, KK Kandimalla bioRxiv, 2022.11. 17.516996, 2022 | 1 | 2022 |
Amyloid-Beta Peptides 40 and 42 Employ Distinct Molecular Pathways for Cell Entry and Intracellular Transit at the Blood–Brain Barrier Endothelium Z Wang, N Sharda, RS Omtri, L Li, KK Kandimalla Molecular Pharmacology 104 (5), 203-213, 2023 | | 2023 |
Trafficking of Amyloid Beta Protein at the Blood Brain Barrier: Novel Insights in Alzheimer's Disease Pathogenesis N Sharda University of Minnesota, 2016 | | 2016 |
Blockade of CXCR2 as a novel approach for cancer chemotherapy N Sharda University of Southern California, 2012 | | 2012 |
Investigating mechanisms in Alzheimer’s disease: Amyloid beta protein trafficking at the blood brain barrier N Sharda | | |
MinneCeutics J Panyam | | |