| “Don’t Phos Over Tau”: recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer’s disease and other tauopathies Y Xia, S Prokop, BI Giasson Molecular neurodegeneration 16 (1), 37, 2021 | 113 | 2021 |
| Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer’s disease and other tauopathies Y Xia, S Prokop, KMM Gorion, JD Kim, ZA Sorrentino, BM Bell, ... Acta Neuropathologica Communications 8, 1-17, 2020 | 71 | 2020 |
| Pathogenic mutation of UBQLN 2 impairs its interaction with UBXD 8 and disrupts endoplasmic reticulum‐associated protein degradation Y Xia, LH Yan, B Huang, M Liu, X Liu, C Huang Journal of neurochemistry 129 (1), 99-106, 2014 | 67 | 2014 |
| Sustained expression of TDP-43 and FUS in motor neurons in rodent's lifetime C Huang, PY Xia, H Zhou International journal of biological sciences 6 (4), 396, 2010 | 61 | 2010 |
| Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression ZA Sorrentino, MS Goodwin, CJ Riffe, JKS Dhillon, Y Xia, KM Gorion, ... Acta neuropathologica communications 7, 1-22, 2019 | 58 | 2019 |
| Precision therapeutic targets for COVID-19 ZA Krumm, GM Lloyd, CP Francis, LH Nasif, DA Mitchell, TE Golde, ... Virology journal 18, 1-22, 2021 | 55 | 2021 |
| β-site amyloid precursor protein cleaving enzyme 1 (BACE1) regulates Notch signaling by controlling the cleavage of Jagged 1 (Jag1) and Jagged 2 (Jag2) proteins W He, J Hu, Y Xia, R Yan Journal of Biological Chemistry 289 (30), 20630-20637, 2014 | 45 | 2014 |
| Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration ZA Sorrentino, Y Xia, C Funk, CJ Riffe, NJ Rutherford, CC Diaz, ... Neurobiology of disease 120, 98-106, 2018 | 42 | 2018 |
| Impaired tau–microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations Y Xia, ZA Sorrentino, JD Kim, KH Strang, CJ Riffe, BI Giasson Journal of Biological Chemistry 294 (48), 18488-18503, 2019 | 26 | 2019 |
| Tau K321/K353 pseudoacetylation within KXGS motifs regulates tau–microtubule interactions and inhibits aggregation Y Xia, BM Bell, BI Giasson Scientific Reports 11 (1), 17069, 2021 | 20 | 2021 |
| Carboxy‐terminal truncations of mouse α‐synuclein alter aggregation and prion‐like seeding ZA Sorrentino, Y Xia, KM Gorion, E Hass, BI Giasson FEBS letters 594 (8), 1271-1283, 2020 | 17 | 2020 |
| Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model GM Lloyd, JKS Dhillon, KMM Gorion, C Riffe, SE Fromholt, Y Xia, ... Molecular Neurodegeneration 16, 1-17, 2021 | 14 | 2021 |
| Disease-, region-and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies EW Hass, ZA Sorrentino, Y Xia, GM Lloyd, JQ Trojanowski, S Prokop, ... Acta neuropathologica communications 9 (1), 146, 2021 | 14 | 2021 |
| Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier–phenotypic variability in autosomal dominant Alzheimer’s disease GM Lloyd, JA Trejo-Lopez, Y Xia, KN McFarland, SJ Lincoln, ... Acta neuropathologica communications 8, 1-9, 2020 | 14 | 2020 |
| Pathogenic MAPT mutations Q336H and Q336R have isoform‐dependent differences in aggregation propensity and microtubule dysfunction Y Xia, L Nasif, BI Giasson Journal of Neurochemistry, 2021 | 9 | 2021 |
| Targeted proteolytic products of τ and α-synuclein in neurodegeneration Y Xia, GM Lloyd, BI Giasson Essays in Biochemistry 65 (7), 905-912, 2021 | 7 | 2021 |
| Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice Y Xia, S Prokop, BM Bell, KMM Gorion, CL Croft, L Nasif, G Xu, CJ Riffe, ... Communications Biology 5 (1), 446, 2022 | 5 | 2022 |
| Tau mutation S356T in the three repeat (3R) isoform leads to microtubule dysfunction and promotes prion-like seeded aggregation Y Xia, BM Bell, JD Kim, B Giasson Frontiers in Neuroscience 17, 869, 2023 | 4 | 2023 |
| Novel SOD1 monoclonal antibodies against the electrostatic loop preferentially detect misfolded SOD1 aggregates Y Xia, Z Chen, G Xu, DR Borchelt, JI Ayers, BI Giasson Neuroscience letters 742, 135553, 2021 | 4 | 2021 |
| Cellular processing of α-synuclein fibrils results in distinct physiological C-terminal truncations with a major cleavage site at residue Glu 114 S Quintin, GM Lloyd, G Paterno, Y Xia, Z Sorrentino, BM Bell, KM Gorion, ... Journal of Biological Chemistry 299 (7), 2023 | 2 | 2023 |
