Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders V Hook, M Yoon, C Mosier, G Ito, S Podvin, BP Head, R Rissman, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1868 (8), 140428, 2020 | 102 | 2020 |
A clinical-stage cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells DM Mellott, CT Tseng, A Drelich, P Fajtová, BC Chenna, DH Kostomiris, ... ACS chemical biology 16 (4), 642-650, 2021 | 93 | 2021 |
Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages JM Gauglitz, CM Aceves, AA Aksenov, G Aleti, J Almaliti, A Bouslimani, ... Food chemistry 302, 125290, 2020 | 57 | 2020 |
Potent anti-SARS-CoV-2 activity by the natural product gallinamide A and analogues via inhibition of cathepsin L AS Ashhurst, AH Tang, P Fajtová, MC Yoon, A Aggarwal, MJ Bedding, ... Journal of medicinal chemistry 65 (4), 2956-2970, 2021 | 48 | 2021 |
Selective neutral pH inhibitor of cathepsin B designed based on cleavage preferences at cytosolic and lysosomal pH conditions MC Yoon, A Solania, Z Jiang, MP Christy, S Podvin, C Mosier, CB Lietz, ... ACS chemical biology 16 (9), 1628-1643, 2021 | 33 | 2021 |
Differential neuropeptidomes of dense core secretory vesicles (DCSV) produced at intravesicular and extracellular pH conditions by proteolytic processing Z Jiang, CB Lietz, S Podvin, MC Yoon, T Toneff, V Hook, AJ O’Donoghue ACS chemical neuroscience 12 (13), 2385-2398, 2021 | 16 | 2021 |
Molecular features of CA-074 pH-dependent inhibition of Cathepsin B MC Yoon, MP Christy, VV Phan, WH Gerwick, G Hook, AJ O’Donoghue, ... Biochemistry 61 (4), 228-238, 2022 | 15 | 2022 |
Cathepsin B dipeptidyl carboxypeptidase and endopeptidase activities demonstrated across a broad pH range MC Yoon, V Hook, AJ O’Donoghue Biochemistry 61 (17), 1904-1914, 2022 | 12 | 2022 |
Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L AS Ashhurst, AH Tang, P Fajtová, M Yoon, A Aggarwal, A Stoye, ... bioRxiv, 2020.12. 23.424111, 2020 | 11 | 2020 |
Distinct dibasic cleavage specificities of neuropeptide-producing cathepsin L and cathepsin V cysteine proteases compared to PC1/3 and PC2 serine proteases MC Yoon, J Ames, C Mosier, Z Jiang, S Podvin, AJ O’Donoghue, V Hook ACS chemical neuroscience 13 (2), 245-256, 2022 | 8 | 2022 |
Discovery of pH-Selective Marine and Plant Natural Product Inhibitors of Cathepsin B Revealed by Screening at Acidic and Neutral pH Conditions VV Phan, C Mosier, MC Yoon, E Glukhov, CR Caffrey, AJ O’Donoghue, ... ACS omega 7 (29), 25346-25352, 2022 | 2 | 2022 |
Distinct cleavage properties of cathepsin B compared to cysteine cathepsins enable the design and validation of a specific substrate for cathepsin B over a broad pH range MC Yoon, V Phan, S Podvin, C Mosier, AJ O’Donoghue, V Hook Biochemistry 62 (15), 2289-2300, 2023 | 1 | 2023 |
Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK J Almaliti, M Alhindy, MC Yoon, V Hook, TF Molinski, AJ O’Donoghue, ... ACS omega 9 (3), 3997-4003, 2024 | | 2024 |
Virtual screening and drug repurposing: together against worm-borne diseases D Rando, R Cogo, J Moraes, M Yoon, Y Sun, D Amarasinghe, C Caffrey, ... MDPI, 2022 | | 2022 |
Discovery of pH-Dependent Protease Cleavage Properties Leads to the Rational Design of Neutral pH-Selective Inhibitor of Cathepsin B Involved in Human Diseases MC Yoon UC San Diego, 2022 | | 2022 |
Assessing the Acceptance of the Pay-For-Performance Model in a Segment of California Pharmacists J Colbert, S McBane, MS Lam, A Blaj, B Zimmers, M Yoon, B Park, T Le, ... Journal of Contemporary Pharmacy Practice 65 (3), 37-42, 2018 | | 2018 |