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Karim, RM
Karim, RM
Department of Molecular Medicine, University of South Florida
Verified email at usf.edu
Title
Cited by
Cited by
Year
Advances of small molecule targeting of kinases
N Berndt, RM Karim, E Schönbrunn
Current opinion in chemical biology 39, 126-132, 2017
702017
Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon
AA Akuffo, AY Alontaga, R Metcalf, MS Beatty, A Becker, JM McDaniel, ...
Journal of Biological Chemistry 293 (16), 6187-6200, 2018
432018
Targeting the BRD4-HOXB13 coregulated transcriptional networks with bromodomain-kinase inhibitors to suppress metastatic castration-resistant prostate cancer
N Nerlakanti, J Yao, DT Nguyen, AK Patel, AM Eroshkin, HR Lawrence, ...
Molecular cancer therapeutics 17 (12), 2796-2810, 2018
302018
Structural basis of inhibitor selectivity in the BRD7/9 subfamily of bromodomains
RM Karim, A Chan, JY Zhu, E Schönbrunn
Journal of medicinal chemistry 63 (6), 3227-3237, 2020
232020
An advanced tool to interrogate BRD9
RM Karim, E Schönbrunn
Journal of Medicinal Chemistry 59 (10), 4459-4461, 2016
192016
Design, synthesis, and characterization of a fluorescence polarization pan-BET bromodomain probe
CN Paulson, X Guan, AM Ayoub, A Chan, RM Karim, WCK Pomerantz, ...
ACS Medicinal Chemistry Letters 9 (12), 1223-1229, 2018
132018
Bivalent BET bromodomain inhibitors confer increased potency and selectivity for BRDT via protein conformational plasticity
X Guan, N Cheryala, RM Karim, A Chan, N Berndt, J Qi, GI Georg, ...
Journal of medicinal chemistry 65 (15), 10441-10458, 2022
122022
Differential BET bromodomain inhibition by dihydropteridinone and pyrimidodiazepinone kinase inhibitors
RM Karim, MJ Bikowitz, A Chan, JY Zhu, D Grassie, A Becker, N Berndt, ...
Journal of medicinal chemistry 64 (21), 15772-15786, 2021
122021
Discovery of dual TAF1-ATR inhibitors and ligand-induced structural changes of the taf1 tandem bromodomain
RM Karim, L Yang, L Chen, MJ Bikowitz, J Lu, D Grassie, ZP Shultz, ...
Journal of Medicinal Chemistry 65 (5), 4182-4200, 2022
112022
Semiparametric quantile regression using family of quantile-based asymmetric densities
I Gijbels, R Karim, A Verhasselt
Computational statistics & data analysis 157, 107129, 2021
102021
Quantile estimation in a generalized asymmetric distributional setting
I Gijbels, R Karim, A Verhasselt
Stochastic Models, Statistics and Their Applications: Dresden, Germany …, 2019
102019
Inhibition of p53 DNA binding by a small molecule protects mice from radiation toxicity
Q Li, RM Karim, M Cheng, M Das, L Chen, C Zhang, HR Lawrence, ...
Oncogene 39 (29), 5187-5200, 2020
72020
Anti-nociceptive, anti-inflammatory and sedating activities of leaf extracts of Premna esculenta (Roxb)
N Qais, ZA Mahmud, MR Karim, SC Bachar
J. Pharm. Res 4 (10), 3463-3465, 2011
72011
Challenges to sustainable supply chain management and their interrelation in the apparel sector of Bangladesh: A Dematel approach
MR Karim, T Ahammed, MS Hossen, N Sakib, SM Mohaimin
European Scientific Journal ESJ 17 (15), 10.19044, 2021
32021
Ligand-induced global conformational changes in TBP-associated factor 1 (TAF1) tandem bromodomains-a novel strategy for targeting the TAF1
RM Karim, Z Schultz, L Yang, J Lopchuk, J Chen, E Schonbrunn
PROTEIN SCIENCE 30 (S1), 148-149, 2021
12021
Discovery and characterization of small molecule inhibitors of the bromodomain containing proteins BRD9 and BRD7 - the targetable subunits of SWI/SNF chromatin remodeling complexes
RM Karim, A Chan, E Schonbrunn
PROTEIN SCIENCE 28, 57-57, 2019
2019
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Articles 1–16