| Advances of small molecule targeting of kinases N Berndt, RM Karim, E Schönbrunn Current Opinion in Chemical Biology 39, 126-132, 2017 | 74 | 2017 |
| Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon AA Akuffo, AY Alontaga, R Metcalf, MS Beatty, A Becker, JM McDaniel, ... Journal of Biological Chemistry 293 (16), 6187-6200, 2018 | 44 | 2018 |
| Targeting the BRD4-HOXB13 coregulated transcriptional networks with bromodomain-kinase inhibitors to suppress metastatic castration-resistant prostate cancer N Nerlakanti, J Yao, DT Nguyen, AK Patel, AM Eroshkin, HR Lawrence, ... Molecular cancer therapeutics 17 (12), 2796-2810, 2018 | 36 | 2018 |
| Structural basis of inhibitor selectivity in the BRD7/9 subfamily of bromodomains RM Karim, A Chan, JY Zhu, E Schönbrunn Journal of medicinal chemistry 63 (6), 3227-3237, 2020 | 27 | 2020 |
| An advanced tool to interrogate BRD9 RM Karim, E Schönbrunn Journal of Medicinal Chemistry 59 (10), 4459-4461, 2016 | 21 | 2016 |
| Differential BET bromodomain inhibition by dihydropteridinone and pyrimidodiazepinone kinase inhibitors RM Karim, MJ Bikowitz, A Chan, JY Zhu, D Grassie, A Becker, N Berndt, ... Journal of medicinal chemistry 64 (21), 15772-15786, 2021 | 17 | 2021 |
| Design, synthesis, and characterization of a fluorescence polarization pan-BET bromodomain probe CN Paulson, X Guan, AM Ayoub, A Chan, RM Karim, WCK Pomerantz, ... ACS Medicinal Chemistry Letters 9 (12), 1223-1229, 2018 | 17 | 2018 |
| Discovery of dual TAF1-ATR inhibitors and ligand-induced structural changes of the taf1 tandem bromodomain RM Karim, L Yang, L Chen, MJ Bikowitz, J Lu, D Grassie, ZP Shultz, ... Journal of Medicinal Chemistry 65 (5), 4182-4200, 2022 | 16 | 2022 |
| Bivalent BET bromodomain inhibitors confer increased potency and selectivity for BRDT via protein conformational plasticity X Guan, N Cheryala, RM Karim, A Chan, N Berndt, J Qi, GI Georg, ... Journal of medicinal chemistry 65 (15), 10441-10458, 2022 | 13 | 2022 |
| Anti-nociceptive, anti-inflammatory and sedating activities of leaf extracts of Premna esculenta (Roxb) N Qais, ZA Mahmud, MR Karim, SC Bachar J. Pharm. Res 4 (10), 3463-3465, 2011 | 8 | 2011 |
| Challenges to sustainable supply chain management and their interrelation in the apparel sector of Bangladesh: A Dematel approach R Karim, T Ahammed, S Hossen, N Sakib, SM Mohaimin European Scientific Journal ESJ 17 (15), 10.19044, 2021 | 7 | 2021 |
| Inhibition of p53 DNA binding by a small molecule protects mice from radiation toxicity Q Li, RM Karim, M Cheng, M Das, L Chen, C Zhang, HR Lawrence, ... Oncogene 39 (29), 5187-5200, 2020 | 7 | 2020 |
| Ligand-induced global conformational changes in TBP-associated factor 1 (TAF1) tandem bromodomains-a novel strategy for targeting the TAF1 RM Karim, Z Schultz, L Yang, J Lopchuk, J Chen, E Schonbrunn PROTEIN SCIENCE 30 (S1), 148-149, 2021 | 1 | 2021 |
| Discovery and characterization of small molecule inhibitors of the bromodomain containing proteins BRD9 and BRD7 - the targetable subunits of SWI/SNF chromatin remodeling complexes RM Karim, A Chan, E Schonbrunn PROTEIN SCIENCE 28, 57-57, 2019 | | 2019 |
