α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease ZA Sorrentino, BI Giasson, P Chakrabarty Acta neuropathologica 138, 1-21, 2019 | 127 | 2019 |
Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies KH Strang, CL Croft, ZA Sorrentino, P Chakrabarty, TE Golde, BI Giasson Journal of biological chemistry 293 (7), 2408-2421, 2018 | 124 | 2018 |
The emerging role of α-synuclein truncation in aggregation and disease ZA Sorrentino, BI Giasson Journal of Biological Chemistry 295 (30), 10224-10244, 2020 | 115 | 2020 |
Robust central nervous system pathology in transgenic mice following peripheral injection of α-Synuclein Fibrils JI Ayers, MM Brooks, NJ Rutherford, JK Howard, ZA Sorrentino, CJ Riffe, ... Journal of virology 91 (2), 10.1128/jvi. 02095-16, 2017 | 86 | 2017 |
Physiological C-terminal truncation of α-synuclein potentiates the prion-like formation of pathological inclusions ZA Sorrentino, N Vijayaraghavan, KM Gorion, CJ Riffe, KH Strang, ... Journal of Biological Chemistry 293 (49), 18914-18932, 2018 | 85 | 2018 |
Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer’s disease and other tauopathies Y Xia, S Prokop, KMM Gorion, JD Kim, ZA Sorrentino, BM Bell, ... Acta Neuropathologica Communications 8, 1-17, 2020 | 71 | 2020 |
Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity ZA Sorrentino, MMT Brooks, V Hudson, NJ Rutherford, TE Golde, ... Molecular neurodegeneration 12, 1-16, 2017 | 68 | 2017 |
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential N Ferreira, H Gram, ZA Sorrentino, E Gregersen, SI Schmidt, L Reimer, ... Acta Neuropathologica 142 (1), 87-115, 2021 | 63 | 2021 |
Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression ZA Sorrentino, MS Goodwin, CJ Riffe, JKS Dhillon, Y Xia, KM Gorion, ... Acta neuropathologica communications 7, 1-22, 2019 | 59 | 2019 |
Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models P Mavroeidi, F Arvanitaki, AK Karakitsou, M Vetsi, I Kloukina, ... Acta neuropathologica 138, 415-441, 2019 | 50 | 2019 |
Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration ZA Sorrentino, Y Xia, C Funk, CJ Riffe, NJ Rutherford, CC Diaz, ... Neurobiology of disease 120, 98-106, 2018 | 43 | 2018 |
Phosphorylation of serine 305 in tau inhibits aggregation KH Strang, ZA Sorrentino, CJ Riffe, KMM Gorion, N Vijayaraghavan, ... Neuroscience letters 692, 187-192, 2019 | 35 | 2019 |
Localized induction of wild-type and mutant alpha-synuclein aggregation reveals propagation along neuroanatomical tracts JI Ayers, CJ Riffe, ZA Sorrentino, J Diamond, E Fagerli, M Brooks, ... Journal of virology 92 (18), 10.1128/jvi. 00586-18, 2018 | 34 | 2018 |
Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course N Tayebi, L Parisiadou, B Berhe, AN Gonzalez, J Serra-Vinardell, ... Molecular genetics and metabolism 122 (4), 198-208, 2017 | 34 | 2017 |
Differential cross-seeding properties of tau and α-synuclein in mouse models of tauopathy and synucleinopathy T Williams, Z Sorrentino, M Weinrich, BI Giasson, P Chakrabarty Brain communications 2 (2), fcaa090, 2020 | 27 | 2020 |
Impaired tau–microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations Y Xia, ZA Sorrentino, JD Kim, KH Strang, CJ Riffe, BI Giasson Journal of Biological Chemistry 294 (48), 18488-18503, 2019 | 26 | 2019 |
α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability A Dagra, DR Miller, M Lin, A Gopinath, F Shaerzadeh, S Harris, ... npj Parkinson's Disease 7 (1), 76, 2021 | 22 | 2021 |
Carboxy‐terminal truncations of mouse α‐synuclein alter aggregation and prion‐like seeding ZA Sorrentino, Y Xia, KM Gorion, E Hass, BI Giasson FEBS letters 594 (8), 1271-1283, 2020 | 17 | 2020 |
Disease-, region-and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies EW Hass, ZA Sorrentino, Y Xia, GM Lloyd, JQ Trojanowski, S Prokop, ... Acta neuropathologica communications 9 (1), 146, 2021 | 16 | 2021 |
Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy EW Hass, ZA Sorrentino, GM Lloyd, NR McFarland, S Prokop, BI Giasson Acta Neuropathologica Communications 9 (1), 80, 2021 | 15 | 2021 |