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Zachary Sorrentino
Zachary Sorrentino
Neurosurgery resident physician, MD, PhD, university of Florida
Verified email at neurosurgery.ufl.edu
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Cited by
Cited by
Year
α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease
ZA Sorrentino, BI Giasson, P Chakrabarty
Acta neuropathologica 138, 1-21, 2019
1272019
Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies
KH Strang, CL Croft, ZA Sorrentino, P Chakrabarty, TE Golde, BI Giasson
Journal of biological chemistry 293 (7), 2408-2421, 2018
1242018
The emerging role of α-synuclein truncation in aggregation and disease
ZA Sorrentino, BI Giasson
Journal of Biological Chemistry 295 (30), 10224-10244, 2020
1152020
Robust central nervous system pathology in transgenic mice following peripheral injection of α-Synuclein Fibrils
JI Ayers, MM Brooks, NJ Rutherford, JK Howard, ZA Sorrentino, CJ Riffe, ...
Journal of virology 91 (2), 10.1128/jvi. 02095-16, 2017
862017
Physiological C-terminal truncation of α-synuclein potentiates the prion-like formation of pathological inclusions
ZA Sorrentino, N Vijayaraghavan, KM Gorion, CJ Riffe, KH Strang, ...
Journal of Biological Chemistry 293 (49), 18914-18932, 2018
852018
Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer’s disease and other tauopathies
Y Xia, S Prokop, KMM Gorion, JD Kim, ZA Sorrentino, BM Bell, ...
Acta Neuropathologica Communications 8, 1-17, 2020
712020
Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity
ZA Sorrentino, MMT Brooks, V Hudson, NJ Rutherford, TE Golde, ...
Molecular neurodegeneration 12, 1-16, 2017
682017
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential
N Ferreira, H Gram, ZA Sorrentino, E Gregersen, SI Schmidt, L Reimer, ...
Acta Neuropathologica 142 (1), 87-115, 2021
632021
Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression
ZA Sorrentino, MS Goodwin, CJ Riffe, JKS Dhillon, Y Xia, KM Gorion, ...
Acta neuropathologica communications 7, 1-22, 2019
592019
Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models
P Mavroeidi, F Arvanitaki, AK Karakitsou, M Vetsi, I Kloukina, ...
Acta neuropathologica 138, 415-441, 2019
502019
Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration
ZA Sorrentino, Y Xia, C Funk, CJ Riffe, NJ Rutherford, CC Diaz, ...
Neurobiology of disease 120, 98-106, 2018
432018
Phosphorylation of serine 305 in tau inhibits aggregation
KH Strang, ZA Sorrentino, CJ Riffe, KMM Gorion, N Vijayaraghavan, ...
Neuroscience letters 692, 187-192, 2019
352019
Localized induction of wild-type and mutant alpha-synuclein aggregation reveals propagation along neuroanatomical tracts
JI Ayers, CJ Riffe, ZA Sorrentino, J Diamond, E Fagerli, M Brooks, ...
Journal of virology 92 (18), 10.1128/jvi. 00586-18, 2018
342018
Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course
N Tayebi, L Parisiadou, B Berhe, AN Gonzalez, J Serra-Vinardell, ...
Molecular genetics and metabolism 122 (4), 198-208, 2017
342017
Differential cross-seeding properties of tau and α-synuclein in mouse models of tauopathy and synucleinopathy
T Williams, Z Sorrentino, M Weinrich, BI Giasson, P Chakrabarty
Brain communications 2 (2), fcaa090, 2020
272020
Impaired tau–microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations
Y Xia, ZA Sorrentino, JD Kim, KH Strang, CJ Riffe, BI Giasson
Journal of Biological Chemistry 294 (48), 18488-18503, 2019
262019
α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability
A Dagra, DR Miller, M Lin, A Gopinath, F Shaerzadeh, S Harris, ...
npj Parkinson's Disease 7 (1), 76, 2021
222021
Carboxy‐terminal truncations of mouse α‐synuclein alter aggregation and prion‐like seeding
ZA Sorrentino, Y Xia, KM Gorion, E Hass, BI Giasson
FEBS letters 594 (8), 1271-1283, 2020
172020
Disease-, region-and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies
EW Hass, ZA Sorrentino, Y Xia, GM Lloyd, JQ Trojanowski, S Prokop, ...
Acta neuropathologica communications 9 (1), 146, 2021
162021
Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy
EW Hass, ZA Sorrentino, GM Lloyd, NR McFarland, S Prokop, BI Giasson
Acta Neuropathologica Communications 9 (1), 80, 2021
152021
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