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Alex Luebbers
Alex Luebbers
Boston University School of Medicine
Verified email at bu.edu
Title
Cited by
Cited by
Year
Atypical activation of the G protein Gαq by the oncogenic mutation Q209P
M Maziarz, A Leyme, A Marivin, A Luebbers, PP Patel, Z Chen, ...
Journal of Biological Chemistry 293 (51), 19586-19599, 2018
312018
A biochemical and genetic discovery pipeline identifies PLCδ4b as a nonreceptor activator of heterotrimeric G-proteins
M Maziarz, S Broselid, V DiGiacomo, JC Park, A Luebbers, ...
Journal of Biological Chemistry 293 (44), 16964-16983, 2018
202018
Optogenetic activation of heterotrimeric G-proteins by LOV2GIVe, a rationally engineered modular protein
M Garcia-Marcos, K Parag-Sharma, A Marivin, M Maziarz, A Luebbers, ...
Elife 9, e60155, 2020
182020
Probing the mutational landscape of regulators of G protein signaling proteins in cancer
V DiGiacomo, M Maziarz, A Luebbers, JM Norris, P Laksono, ...
Science signaling 13 (617), eaax8620, 2020
172020
Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different G protein subunits
JC Park, A Luebbers, M Dao, A Semeano, AM Nguyen, ...
Molecular cell 83 (14), 2540-2558. e12, 2023
92023
Direct interrogation of context-dependent GPCR activity with a universal biosensor platform
R Janicot, M Maziarz, JC Park, J Zhao, A Luebbers, E Green, CE Philibert, ...
Cell, 2024
52024
Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer
J Zhao, V DiGiacomo, M Ferreras-Gutierrez, S Dastjerdi, ...
Proceedings of the National Academy of Sciences 120 (18), e2213140120, 2023
52023
Dissecting the molecular basis for the modulation of neurotransmitter GPCR signaling by GINIP
A Luebbers, AJ Gonzalez-Hernandez, M Zhou, SJ Eyles, J Levitz, ...
Structure 32 (1), 47-59. e7, 2024
32024
Gαs inhibitor peptide probes for the spatiotemporal interrogation of signaling
J Zhao, A Luebbers, S Savransky, M Maziarz, JP Vilardaga, ...
Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024
2024
Dissecting the molecular basis of neurotransmitter signaling modulation by GINIP
A Luebbers
Boston University, 2024
2024
Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression
J Zhao, V DiGiacomo, M Ferreras-Gutierrez, S Dastjerdi, AI de Opakua, ...
bioRxiv, 2023.02. 18.529092, 2023
2023
Identification of Peptide Sequence Served as Genetically-Encoded or Chemical Probes to Inhibit Gαs in Cells
J Zhao, A Luebbers, M Maziarz, M Garcia-Marcos
Journal of Biological Chemistry 299 (3), S737, 2023
2023
Dissecting the molecular basis for the modulation of neurotransmitter GPCR signaling by a Gαi-binding protein
A Luebbers, M Zhou, S Eyles, M Garcia-Marcos
Journal of Biological Chemistry 299 (3), S762, 2023
2023
Identification of Peptide Inhibitors of Gαs that Block its Effector Binding Site
A Luebbers, M Maziarz, M Garcia‐Marcos
The FASEB Journal 36, 2022
2022
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