| Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2′-deoxyzebularine FM Barzak, S Harjes, MV Kvach, HM Kurup, GB Jameson, VV Filichev, ... Organic & Biomolecular Chemistry 17 (43), 9435-9441, 2019 | 30 | 2019 |
| Differential Inhibition of APOBEC3 DNA‐Mutator Isozymes by Fluoro‐and Non‐Fluoro‐Substituted 2′‐Deoxyzebularine Embedded in Single‐Stranded DNA MV Kvach, FM Barzak, S Harjes, HAM Schares, HM Kurup, KF Jones, ... Chembiochem 21 (7), 1028-1035, 2020 | 22 | 2020 |
| Design, synthesis, and evaluation of a cross-linked oligonucleotide as the first nanomolar inhibitor of APOBEC3A HM Kurup, MV Kvach, S Harjes, FM Barzak, GB Jameson, E Harjes, ... Biochemistry 61 (22), 2568-2578, 2022 | 9 | 2022 |
| Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A S Harjes, HM Kurup, AE Rieffer, M Bayarjargal, J Filitcheva, Y Su, TK Hale, ... Nature communications 14 (1), 6382, 2023 | 8 | 2023 |
| A highly efficient and enantioselective synthesis of EEHP and EMHP: intermediates of PPAR agonists M Gangar, M Harikrishnan, S Goyal, MN Mungalpara, VA Nair Tetrahedron Letters 57 (31), 3462-3467, 2016 | 7 | 2016 |
| Small-angle X-ray scattering models of APOBEC3B catalytic domain in a complex with a single-stranded DNA inhibitor FM Barzak, TM Ryan, MV Kvach, HM Kurup, H Aihara, RS Harris, ... Viruses 13 (2), 290, 2021 | 6 | 2021 |
| Anti selective glycolate aldol reactions of (S)-4-isopropyl-1-[(R)-1-phenylethyl] imidazolidin-2-one: Application towards the asymmetric synthesis of 8-4′-oxyneolignans M Gangar, A Ittuveetil, S Goyal, A Pal, M Harikrishnan, VA Nair RSC advances 6 (104), 102116-102126, 2016 | 6 | 2016 |
| Seven-membered ring nucleobases as inhibitors of human cytidine deaminase and APOBEC3A HM Kurup, MV Kvach, S Harjes, GB Jameson, E Harjes, VV Filichev Organic & Biomolecular Chemistry 21 (24), 5117-5128, 2023 | 5 | 2023 |
| Small-Angle X-ray Scattering (SAXS) Measurements of APOBEC3G Provide Structural Basis for Binding of Single-Stranded DNA and Processivity FM Barzak, TM Ryan, N Mohammadzadeh, S Harjes, MV Kvach, ... Viruses 14 (9), 1974, 2022 | 3 | 2022 |
| Uncoupling molecular testing for SARS-CoV-2 from international supply chains JAL Stanton, R O'Brien, RJ Hall, A Chernyavtseva, HJ Ha, L Jelley, ... Frontiers in Public Health 9, 808751, 2022 | 3 | 2022 |
| Asymmetric glycolate alkylation approach towards total synthesis of 8-O. 6′ and 8-O. 4′-neolignans M Gangar, M Chouhan, S Goyal, M Harikrishnan, R Chandran, A Ittuveetil, ... Tetrahedron letters 57 (52), 5931-5934, 2016 | 3 | 2016 |
| Synthesis of 1, 4-azaphosphinine nucleosides and evaluation as inhibitors of human cytidine deaminase and APOBEC3A MV Kvach, S Harjes, HM Kurup, GB Jameson, E Harjes, VV Filichev Beilstein Journal of Organic Chemistry 20 (1), 1088-1098, 2024 | | 2024 |
| Single stranded dna enzyme inhibitors FMY Barzak, VV Filichev, E Harjes, S Harjes, GB Jameson, HM Kurup, ... US Patent App. 18/262,896, 2024 | | 2024 |
| Synthesis of 1, 4-azaphosphinine pyrimidine nucleosides and their evaluation as inhibitors of human cytidine deaminase and APOBEC3A MV Kvach, S Harjes, HM Kurup, GB Jameson, E Harjes, VV Filichev Beilstein Archives 2024 (1), 9, 2024 | | 2024 |
| Publication Date 08 Feb. 2024 MV Kvach, S Harjes, HM Kurup, EH Jameson, VV Filichev | | 2024 |
| Cross-linked DNA with carbazole pseudo-nucleoside enables potent inhibition of the cancer DNA-and RNA-mutating enzyme APOBEC3A H Kurup, S Harjes, Y Su, T Hall, G Jameson, E Harjes, V Filichev | | 2023 |
| Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A G Jameson, S Harjes, H Kurup, A Rieffer, M Bayarjargal, J Filichetva, Y Su, ... | | 2023 |
| Structural basis of modified-DNA inhibitors that competitively restrict DNA-mutating (C--> U) activity of innate-immune system enzyme APOBEC3A hijacked by cancer cells to … GB Jameson, S Harjes, HM Kurup, M Bayarjargal, J Filitcheva, Y Su, ... Acta Cryst 79, C692, 2023 | | 2023 |
| Design, synthesis, and evaluation of cross-linked single-stranded DNAs as inhibitors of APOBEC3 enzymes: a thesis presented in partial fulfilment of the requirements of the … HM Kurup Massey University, 2021 | | 2021 |
| Oligonucleotide-based therapeutic agents: challenges and advances. HM Kurup, VV Filichev Chemistry in New Zealand (Christchurch) 84 (3), 2020 | | 2020 |
