| ERK activation globally downregulates miRNAs through phosphorylating exportin-5 HL Sun, R Cui, JK Zhou, K Teng, YH Hsiao, K Nakanishi, M Fassan, Z Luo, ... Cancer cell 30 (5), 723-736, 2016 | 139 | 2016 |
| Synthesis and Biological Evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as Potent Histone Deacetylase Inhibitors with Antitumor Activity in Vivo MJ Lai, HL Huang, SL Pan, YM Liu, CY Peng, HY Lee, TK Yeh, PH Huang, ... Journal of medicinal chemistry 55 (8), 3777-3791, 2012 | 114 | 2012 |
| Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent in Vivo Pharmacodynamic Activity and Antitumor Efficacy SY Lin, TK Yeh, CC Kuo, JS Song, MF Cheng, FY Liao, MW Chao, ... Journal of Medicinal Chemistry 59 (1), 419-430, 2016 | 79 | 2016 |
| Function of integrin-linked kinase in modulating the stemness of IL-6–abundant breast cancer cells by regulating γ-secretase–mediated notch1 activation in caveolae EC Hsu, SK Kulp, HL Huang, HJ Tu, SB Salunke, NJ Sullivan, D Sun, ... Neoplasia 17 (6), 497-508, 2015 | 50 | 2015 |
| 1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC R Ojha, HL Huang, WC HuangFu, YW Wu, K Nepali, MJ Lai, CJ Su, ... European Journal of Medicinal Chemistry 150, 667-677, 2018 | 47 | 2018 |
| Lanatoside C, a cardiac glycoside, acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells MW Chao, TH Chen, HL Huang, YW Chang, WC HuangFu, YC Lee, ... Scientific reports 7 (1), 1-12, 2017 | 40 | 2017 |
| Potential effects of CXCL9 and CCL20 on cardiac fibrosis in patients with myocardial infarction and isoproterenol-treated rats CF Lin, CJ Su, JH Liu, ST Chen, HL Huang, SL Pan Journal of clinical medicine 8 (5), 659, 2019 | 37 | 2019 |
| N-Sulfonyl-aminobiaryls as Antitubulin Agents and Inhibitors of Signal Transducers and Activators of Transcription 3 (STAT3) Signaling MJ Lai, HY Lee, HY Chuang, LH Chang, AC Tsai, MC Chen, HL Huang, ... Journal of Medicinal Chemistry 58 (16), 6549-6558, 2015 | 33 | 2015 |
| Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo R Ojha, K Nepali, CH Chen, KH Chuang, TY Wu, TE Lin, KC Hsu, ... European Journal of Medicinal Chemistry 190, 112086, 2020 | 32 | 2020 |
| Anticancer Activity of MPT0E028, a Novel Potent Histone Deacetylase Inhibitor, in Human Colorectal Cancer HCT116 Cells In Vitro and In Vivo HL Huang, HY Lee, AC Tsai, CY Peng, MJ Lai, JC Wang, SL Pan, ... Public Library of Science 7 (8), e43645, 2012 | 32 | 2012 |
| 2-(Phenylsulfonyl) quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase HY Lee, CY Chang, CJ Su, HL Huang, S Mehndiratta, YH Chao, CM Hsu, ... European Journal of Medicinal Chemistry 122, 92-101, 2016 | 31 | 2016 |
| TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis HL Huang, YM Liu, TY Sung, TC Huang, YW Cheng, JP Liou, SL Pan Theranostics 9 (22), 6676, 2019 | 28 | 2019 |
| A novel selective JAK2 inhibitor identified using pharmacological interactions TE Lin, WC HuangFu, MW Chao, TY Sung, CD Chang, YY Chen, ... Frontiers in pharmacology 9, 1379, 2018 | 28 | 2018 |
| Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer EC Hsu, SK Kulp, HL Huang, HJ Tu, MW Chao, YC Tseng, MC Yang, ... Carcinogenesis 37 (4), 430-442, 2016 | 28 | 2016 |
| 1‐Arylsulfonyl‐5‐(N‐hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors HY Lee, CR Yang, MJ Lai, HL Huang, YL Hsieh, YM Liu, TK Yeh, YH Li, ... ChemBioChem 14 (10), 1248-1254, 2013 | 26 | 2013 |
| 4-Indolyl-N-hydroxyphenylacrylamides as potent HDAC class I and IIB inhibitors in vitro and in vivo S Mehndiratta, RS Wang, HL Huang, CJ Su, CM Hsu, YW Wu, SL Pan, ... European Journal of Medicinal Chemistry 134, 13-23, 2017 | 25 | 2017 |
| MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis and potentiates antineoplastic effect of cisplatin in ovarian cancer HL Huang, MW Chao, YC Li, LH Chang, CH Chen, MC Chen, CC Cheng, ... Scientific reports 6 (1), 1-11, 2016 | 19 | 2016 |
| 1, 4-Naphthoquinones as inhibitors of Itch, a HECT domain-E3 ligase, and tumor growth suppressors in multiple myeloma YM Liu, WC HuangFu, HL Huang, WC Wu, YL Chen, Y Yen, HL Huang, ... European Journal of Medicinal Chemistry 140, 84-91, 2017 | 17 | 2017 |
| Biological evaluation of selected flavonoids as inhibitors of MNKs targeting acute myeloid leukemia LC Chen, HL Huang, WC HuangFu, SC Yen, ST Ngo, YW Wu, TE Lin, ... Journal of Natural Products 83 (10), 2967-2975, 2020 | 16 | 2020 |
| Investigation of selected flavonoid derivatives as potent FLT3 inhibitors for the potential treatment of acute myeloid leukemia SC Yen, LC Chen, HL Huang, ST Ngo, YW Wu, TE Lin, TY Sung, ST Lien, ... Journal of Natural Products 84 (1), 1-10, 2021 | 15 | 2021 |
