| Cellular functions, mechanism of action, and regulation of FtsH protease K Ito, Y Akiyama Annu. Rev. Microbiol. 59, 211-231, 2005 | 464 | 2005 |
| FtsH is required for proteolytic elimination of uncomplexed forms of SecY, an essential protein translocase subunit. A Kihara, Y Akiyama, K Ito Proceedings of the National Academy of Sciences 92 (10), 4532-4536, 1995 | 357 | 1995 |
| Identification and characterization of an Escherichia coli gene required for the formation of correctly folded alkaline phosphatase, a periplasmic enzyme. S Kamitani, Y Akiyama, K Ito The EMBO journal 11 (1), 57-62, 1992 | 352 | 1992 |
| Effects of mutations in heat‐shock genes groES and groEL on protein export in Escherichia coli. N Kusukawa, T Yura, C Ueguchi, Y Akiyama, K Ito The EMBO journal 8 (11), 3517-3521, 1989 | 328 | 1989 |
| Topology analysis of the SecY protein, an integral membrane protein involved in protein export in Escherichia coli. Y Akiyama, K Ito The EMBO Journal 6 (11), 3465-3470, 1987 | 313 | 1987 |
| YaeL (EcfE) activates the ςE pathway of stress response through a site-2 cleavage of anti-ςE, RseA K Kanehara, K Ito, Y Akiyama Genes & development 16 (16), 2147-2155, 2002 | 312 | 2002 |
| A protease complex in the Escherichia coli plasma membrane: HflKC (HflA) forms a complex with FtsH (HflB), regulating its proteolytic activity against SecY. A Kihara, Y Akiyama, K Ito The EMBO journal 15 (22), 6122-6131, 1996 | 228 | 1996 |
| FtsH (HflB) is an ATP-dependent protease selectively acting on SecY and some other membrane proteins Y Akiyama, A Kihara, H Tokuda, K Ito Journal of Biological Chemistry 271 (49), 31196-31201, 1996 | 206 | 1996 |
| RseP (YaeL), an Escherichia coli RIP protease, cleaves transmembrane sequences Y Akiyama, K Kanehara, K Ito The EMBO journal 23 (22), 4434-4442, 2004 | 191 | 2004 |
| Involvement of FtsH in protein assembly into and through the membrane. I. Mutations that reduce retention efficiency of a cytoplasmic reporter. Y Akiyama, T Ogura, K Ito Journal of Biological Chemistry 269 (7), 5218-5224, 1994 | 189 | 1994 |
| Cell growth and lambda phage development controlled by the same essential Escherichia coli gene, ftsH/hflB. C Herman, T Ogura, T Tomoyasu, S Hiraga, Y Akiyama, K Ito, R Thomas, ... Proceedings of the National Academy of Sciences 90 (22), 10861-10865, 1993 | 176 | 1993 |
| Subunit a of proton ATPase F0 sector is a substrate of the FtsH protease in Escherichia coli Y Akiyama, A Kihara, K Ito FEBS letters 399 (1-2), 26-28, 1996 | 165 | 1996 |
| In vitro catalysis of oxidative folding of disulfide-bonded proteins by the Escherichia coli dsbA (ppfA) gene product. Y Akiyama, S Kamitani, N Kusukawa, K Ito Journal of Biological Chemistry 267 (31), 22440-22445, 1992 | 162 | 1992 |
| Host regulation of lysogenic decision in bacteriophage λ: transmembrane modulation of FtsH (HflB), the cII degrading protease, by HflKC (HflA) A Kihara, Y Akiyama, K Ito Proceedings of the National Academy of Sciences 94 (11), 5544-5549, 1997 | 156 | 1997 |
| The SecY membrane component of the bacterial protein export machinery: analysis by new electrophoretic methods for integral membrane proteins. Y Akiyama, K Ito The EMBO Journal 4 (12), 3351-3356, 1985 | 156 | 1985 |
| SecY protein, a membrane-embedded secretion factor of E. coli, is cleaved by the ompT protease in vitro Y Akiyama, K Ito Biochemical and biophysical research communications 167 (2), 711-715, 1990 | 154 | 1990 |
| Dislocation of membrane proteins in FtsH‐mediated proteolysis A Kihara, Y Akiyama, K Ito The EMBO Journal, 1999 | 144 | 1999 |
| Effects of the chaperonin GroE on the refolding of tryptophanase from Escherichia coli. Refolding is enhanced in the presence of ADP. T Mizobata, Y Akiyama, K Ito, N Yumoto, Y Kawata Journal of Biological Chemistry 267 (25), 17773-17779, 1992 | 144 | 1992 |
| Differential in vivo roles played by DsbA and DsbC in the formation of protein disulfide bonds M Sone, Y Akiyama, K Ito Journal of Biological Chemistry 272 (16), 10349-10352, 1997 | 142 | 1997 |
| The Cpx stress response system of Escherichia coli senses plasma membrane proteins and controls HtpX, a membrane protease with a cytosolic active site N Shimohata, S Chiba, N Saikawa, K Ito, Y Akiyama Genes to Cells 7 (7), 653-662, 2002 | 141 | 2002 |
