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Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans L Che, W Chi, Y Qiao, J Zhang, X Song, Y Liu, L Li, J Jia, MG Pilo, J Wang, ... Gut 69 (1), 177-186, 2020 | 146 | 2020 |
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice S Zhang, X Song, D Cao, Z Xu, B Fan, L Che, J Hu, B Chen, M Dong, ... Journal of hepatology 67 (6), 1194-1203, 2017 | 96 | 2017 |
Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice J Wang, M Dong, Z Xu, X Song, S Zhang, YU Qiao, L Che, J Gordan, K Hu, ... Oncogene 37 (24), 3229-3242, 2018 | 93 | 2018 |
Glucose catabolism in liver tumors induced by c-MYC can be sustained by various PKM1/PKM2 ratios and pyruvate kinase activities A Méndez-Lucas, X Li, J Hu, L Che, X Song, J Jia, J Wang, C Xie, ... Cancer research 77 (16), 4355-4364, 2017 | 79 | 2017 |
Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells D Cao, X Song, L Che, X Li, MG Pilo, G Vidili, A Porcu, A Solinas, ... Liver International 37 (1), 80-89, 2017 | 73 | 2017 |
Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma R Shang, X Song, P Wang, Y Zhou, X Lu, J Wang, M Xu, X Chen, ... Gut 70 (9), 1746-1757, 2021 | 71 | 2021 |
Combined CDK4/6 and pan-mTOR inhibition is synergistic against intrahepatic cholangiocarcinoma X Song, X Liu, H Wang, J Wang, Y Qiao, A Cigliano, K Utpatel, S Ribback, ... Clinical Cancer Research 25 (1), 403-413, 2019 | 66 | 2019 |
Glycycoumarin ameliorates alcohol-induced hepatotoxicity via activation of Nrf2 and autophagy X Song, S Yin, Y Huo, M Liang, L Fan, M Ye, H Hu Free Radical Biology and Medicine 89, 135-146, 2015 | 66 | 2015 |
Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis J Wang, H Wang, M Peters, N Ding, S Ribback, K Utpatel, A Cigliano, ... Journal of hepatology 71 (4), 742-752, 2019 | 51 | 2019 |
Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation X Song, H Xu, P Wang, J Wang, S Affo, H Wang, M Xu, B Liang, L Che, ... Journal of hepatology 75 (4), 888-899, 2021 | 49 | 2021 |
p53 activation contributes to patulin-induced nephrotoxicity via modulation of reactive oxygen species generation H Jin, S Yin, X Song, E Zhang, L Fan, H Hu Scientific reports 6 (1), 24455, 2016 | 48 | 2016 |
Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway E Zhang, S Yin, X Song, L Fan, H Hu Scientific Reports 6 (1), 38138, 2016 | 42 | 2016 |
Axis inhibition protein 1 (Axin1) deletion–induced hepatocarcinogenesis requires intact β‐catenin but not notch cascade in mice Y Qiao, J Wang, E Karagoz, B Liang, X Song, R Shang, K Evert, M Xu, ... Hepatology 70 (6), 2003-2017, 2019 | 40 | 2019 |
Involvement of autophagy induction in penta-1, 2, 3, 4, 6-O-galloyl-β-D-glucose-induced senescence-like growth arrest in human cancer cells Y Dong, S Yin, C Jiang, X Luo, X Guo, C Zhao, L Fan, Y Meng, J Lu, ... Autophagy 10 (2), 296-310, 2014 | 39 | 2014 |
TAZ is indispensable for c-MYC-induced hepatocarcinogenesis H Wang, S Zhang, Y Zhang, J Jia, J Wang, X Liu, J Zhang, X Song, ... Journal of hepatology 76 (1), 123-134, 2022 | 33 | 2022 |
TEA domain transcription factor 4 is the major mediator of Yes-associated protein oncogenic activity in mouse and human hepatoblastoma J Zhang, P Liu, J Tao, P Wang, Y Zhang, X Song, L Che, P Sumazin, ... The American Journal of Pathology 189 (5), 1077-1090, 2019 | 28 | 2019 |
Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase X Song, S Yin, E Zhang, L Fan, M Ye, Y Zhang, H Hu Oncotarget 7 (40), 65732, 2016 | 28 | 2016 |
TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis B Liang, Y Zhou, M Qian, M Xu, J Wang, Y Zhang, X Song, H Wang, S Lin, ... Journal of hepatology 75 (1), 120-131, 2021 | 27 | 2021 |
Distinct and overlapping roles of hippo effectors YAP and TAZ during human and mouse hepatocarcinogenesis H Wang, J Wang, S Zhang, J Jia, X Liu, J Zhang, P Wang, X Song, L Che, ... Cellular and molecular gastroenterology and hepatology 11 (4), 1095-1117, 2021 | 27 | 2021 |