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Brendan Dwyer
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The hairpin form of r (G4C2) exp in c9ALS/FTD is repeat-associated non-ATG translated and a target for bioactive small molecules
ZF Wang, A Ursu, JL Childs-Disney, R Guertler, WY Yang, V Bernat, ...
Cell chemical biology 26 (2), 179-190. e12, 2019
982019
Drugging the RNA world
MD Disney, BG Dwyer, JL Childs-Disney
Cold Spring Harbor perspectives in biology 10 (11), a034769, 2018
602018
Ethynylation of cysteine residues: from peptides to proteins in vitro and in living cells
R Tessier, RK Nandi, BG Dwyer, D Abegg, C Sornay, J Ceballos, S Erb, ...
Angewandte Chemie International Edition 59 (27), 10961-10970, 2020
592020
Discovery and evaluation of new activity‐based probes for serine hydrolases
C Wang, D Abegg, BG Dwyer, A Adibekian
ChemBioChem 20 (17), 2212-2216, 2019
272019
Ruthenium anticancer agent KP1019 binds more tightly than NAMI-A to tRNAPhe
BG Dwyer, E Johnson, E Cazares, KLMF Holman, SR Kirk
Journal of Inorganic Biochemistry 182, 177-183, 2018
252018
Total synthesis and target identification of the curcusone diterpenes
C Cui, BG Dwyer, C Liu, D Abegg, ZJ Cai, DG Hoch, X Yin, N Qiu, JQ Liu, ...
Journal of the American Chemical Society 143 (11), 4379-4386, 2021
222021
Combined omics approach identifies gambogic acid and related xanthones as covalent inhibitors of the serine palmitoyltransferase complex
DG Hoch, D Abegg, JT Hannich, D Pechalrieu, A Shuster, BG Dwyer, ...
Cell chemical biology 27 (5), 586-597. e12, 2020
212020
Cold Spring Harbor Perspect
MD Disney, BG Dwyer, JL Childs-Disney
Biol 10, a034769, 2018
132018
Chemoproteomics‐Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism
BG Dwyer, C Wang, D Abegg, B Racioppo, N Qiu, Z Zhao, D Pechalrieu, ...
Angewandte Chemie International Edition 60 (6), 3071-3079, 2021
122021
PredMP: a web
S Wang, S Fei, Z Wang, Y Li, J Xu
Bioinformatics, 2018
52018
Proteomics‐Based Discovery of First‐in‐Class Chemical Probes for Programmed Cell Death Protein 2 (PDCD2)
W Ji, WS Byun, W Lu, X Zhu, KA Donovan, BG Dwyer, J Che, L Yuan, ...
Angewandte Chemie International Edition 62 (43), e202308292, 2023
12023
Total synthesis and chemoproteomics connect curcusone diterpenes with oncogenic protein BRAT1
C Cui, BG Dwyer, C Liu, D Abegg, Z Cai, D Hoch, X Yin, N Qiu, J Liu, ...
12020
Curcusone diterpenoids and uses thereof
M Dai, C Cui, Z Cai, A Adibekian, B Dwyer
US Patent App. 18/445,087, 2023
2023
Chemoproteomics-enabled de novo discovery of metallothionein degraders
B Racioppo, D Pechalrieu, D Abegg, B Dwyer, A Adibekian
MOLECULAR & CELLULAR PROTEOMICS 21 (8), S78-S78, 2022
2022
Chapter V. A Kinetically Attenuated Ethynylbenziodoxole Probe for Chemoproteomic Profiling Covalent Reversible and Slow-Binding Drugs
C Reversible, BG Dwyer, R Tessier, D Abegg, Z Zhao, DG Hoch, ...
Chemoproteomic Tools for Profiling Bioactive Small Molecules: From De Novo …, 2022
2022
Chapter III. Chemoproteomics-Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism
BG Dwyer, C Wang, D Abegg, B Racioppo, N Qiu, Z Zhao, D Pechalrieu, ...
Chemoproteomic Tools for Profiling Bioactive Small Molecules: From De Novo …, 2022
2022
Chemoproteomic Tools for Profiling Bioactive Small Molecules: From de novo Photopharmacology to Cysteine-Reactive Covalent Drugs to Natural Product Target …
BG Dwyer
The Scripps Research Institute, 2022
2022
Cover Feature: Discovery and Evaluation of New Activity‐Based Probes for Serine Hydrolases (ChemBioChem 17/2019)
C Wang, D Abegg, BG Dwyer, A Adibekian
ChemBioChem 20 (17), 2161-2161, 2019
2019
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