David Oupický
David Oupický
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Tumor-penetrating nanoparticles for enhanced anticancer activity of combined photodynamic and hypoxia-activated therapy
Y Wang, Y Xie, J Li, ZH Peng, Y Sheinin, J Zhou, D Oupický
ACS nano 11 (2), 2227-2238, 2017
A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids
ML Read, S Singh, Z Ahmed, M Stevenson, SS Briggs, D Oupicky, ...
Nucleic acids research 33 (9), e86-e86, 2005
Temperature-controlled uptake and release in PNIPAM-modified porous silica nanoparticles
YZ You, KK Kalebaila, SL Brock, D Oupicky
Chemistry of Materials 20 (10), 3354-3359, 2008
Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA
MA Wolfert, PR Dash, O Nazarova, D Oupicky, LW Seymour, S Smart, ...
Bioconjugate chemistry 10 (6), 993-1004, 1999
Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation
D Oupicky, M Ogris, KA Howard, PR Dash, K Ulbrich, LW Seymour
Molecular Therapy 5 (4), 463-472, 2002
Novel vectors for gene delivery formed by self-assembly of DNA with poly (L-lysine) grafted with hydrophilic polymers
V Toncheva, MA Wolfert, PR Dash, D Oupicky, K Ulbrich, LW Seymour, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1380 (3), 354-368, 1998
Laterally stabilized complexes of DNA with linear reducible polycations: strategy for triggered intracellular activation of DNA delivery vectors
D Oupický, AL Parker, LW Seymour
Journal of the American Chemical Society 124 (1), 8-9, 2002
Physical properties and in vitro transfection efficiency of gene delivery vectors based on complexes of DNA with synthetic polycations
T Reschel, Č Koňák, D Oupický, LW Seymour, K Ulbrich
Journal of controlled release 81 (1-2), 201-217, 2002
Decreased binding to proteins and cells of polymeric gene delivery vectors surface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin
PR Dash, ML Read, KD Fisher, KA Howard, M Wolfert, D Oupicky, V Subr, ...
Journal of Biological Chemistry 275 (6), 3793-3802, 2000
Recent advances in delivery of drug–nucleic acid combinations for cancer treatment
J Li, Y Wang, Y Zhu, D Oupický
Journal of controlled release 172 (2), 589-600, 2013
Reducible poly (2-dimethylaminoethyl methacrylate): synthesis, cytotoxicity, and gene delivery activity
YZ You, DS Manickam, QH Zhou, D Oupický
Journal of Controlled Release 122 (3), 217-225, 2007
Vectors based on reducible polycations facilitate intracellular release of nucleic acids
ML Read, KH Bremner, D Oupický, NK Green, PF Searle, LW Seymour
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2003
DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers
D Oupický, Č Koňák, K Ulbrich, MA Wolfert, LW Seymour
Journal of Controlled Release 65 (1-2), 149-171, 2000
Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo
D Oupický, RC Carlisle, LW Seymour
Gene therapy 8 (9), 713-724, 2001
Emerging roles of the CXCL12/CXCR4 axis in pancreatic cancer progression and therapy
RL Sleightholm, BK Neilsen, J Li, MM Steele, RK Singh, MA Hollingsworth, ...
Pharmacology & therapeutics 179, 158-170, 2017
Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate‐mediated targeting in vitro and prolonged plasma circulation in vivo
CM Ward, M Pechar, D Oupicky, K Ulbrich, LW Seymour
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2002
Steric Stabilization of poly-l-Lysine/DNA Complexes by the Covalent Attachment of Semitelechelic poly[N-(2-Hydroxypropyl)methacrylamide]
D Oupický, KA Howard, Č Koňák, PR Dash, K Ulbrich, LW Seymour
Bioconjugate chemistry 11 (4), 492-501, 2000
Enhanced gene and siRNA delivery by polycation-modified mesoporous silica nanoparticles loaded with chloroquine
SR Bhattarai, E Muthuswamy, A Wani, M Brichacek, AL Castańeda, ...
Pharmaceutical research 27, 2556-2568, 2010
Gene delivery in vitro and in vivo from bioreducible multilayered polyelectrolyte films of plasmid DNA
J Blacklock, YZ You, QH Zhou, G Mao, D Oupický
Biomaterials 30 (5), 939-950, 2009
Targeting pulmonary tumor microenvironment with CXCR4-inhibiting nanocomplex to enhance anti–PD-L1 immunotherapy
Z Li, Y Wang, Y Shen, C Qian, D Oupicky, M Sun
Science advances 6 (20), eaaz9240, 2020
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