Leif W. Ellisen
Leif W. Ellisen
Professor of Medicine, Harvard Medical School
Verified email at - Homepage
Cited by
Cited by
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
M Meyerson, CM Counter, EN Eaton, LW Ellisen, P Steiner, SD Caddle, ...
cell 90 (4), 785-795, 1997
TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
LW Ellisen, J Bird, DC West, AL Soreng, TC Reynolds, SD Smith, J Sklar
Cell 66 (4), 649-661, 1991
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
J Brugarolas, K Lei, RL Hurley, BD Manning, JH Reiling, E Hafen, ...
Genes & development 18 (23), 2893-2904, 2004
Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer
DP Silver, AL Richardson, AC Eklund, ZC Wang, Z Szallasi, Q Li, N Juul, ...
Journal of clinical oncology 28 (7), 1145, 2010
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1α
L Zhong, A D'Urso, D Toiber, C Sebastian, RE Henry, DD Vadysirisack, ...
Cell 140 (2), 280-293, 2010
Hypoxia regulates TSC1/2–mTOR signaling and tumor suppression through REDD1-mediated 14–3–3 shuttling
MP DeYoung, P Horak, A Sofer, D Sgroi, LW Ellisen
Genes & development 22 (2), 239-251, 2008
Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping
DR Borger, KK Tanabe, KC Fan, HU Lopez, VR Fantin, KS Straley, ...
The oncologist 17 (1), 72-79, 2012
Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1
DP Harkin, JM Bean, D Miklos, YH Song, VB Truong, C Englert, ...
Cell 97 (5), 575-586, 1999
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase
CM Counter, M Meyerson, EN Eaton, LW Ellisen, SD Caddle, DA Haber, ...
Oncogene 16 (9), 1217-1222, 1998
PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition
YH Ibrahim, C García-García, V Serra, L He, K Torres-Lockhart, A Prat, ...
Cancer discovery 2 (11), 1036-1047, 2012
Regulation of mTOR and cell growth in response to energy stress by REDD1
A Sofer, K Lei, CM Johannessen, LW Ellisen
Molecular and cellular biology, 2005
REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species
LW Ellisen, KD Ramsayer, CM Johannessen, A Yang, H Beppu, K Minda, ...
Molecular cell 10 (5), 995-1005, 2002
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues
KA Kolquist, LW Ellisen, CM Counter, MM Meyerson, LK Tan, ...
Nature genetics 19 (2), 182-186, 1998
p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis
JW Rocco, CO Leong, N Kuperwasser, MP DeYoung, LW Ellisen
Cancer cell 9 (1), 45-56, 2006
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
P Polak, J Kim, LZ Braunstein, R Karlic, NJ Haradhavala, G Tiao, ...
Nature genetics 49 (10), 1476-1486, 2017
Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next‐generation sequencing with a 25‐gene panel
N Tung, C Battelli, B Allen, R Kaldate, S Bhatnagar, K Bowles, K Timms, ...
Cancer 121 (1), 25-33, 2015
p63 regulates an adhesion programme and cell survival in epithelial cells
DK Carroll, JS Carroll, CO Leong, F Cheng, M Brown, AA Mills, JS Brugge, ...
Nature cell biology 8 (6), 551-561, 2006
TBCRC009: a multicenter phase II clinical trial of platinum monotherapy with biomarker assessment in metastatic triple-negative breast cancer
SJ Isakoff, EL Mayer, L He, TA Traina, LA Carey, KJ Krag, HS Rugo, ...
Journal of clinical oncology 33 (17), 1902, 2015
Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice
LV Sequist, RS Heist, AT Shaw, P Fidias, R Rosovsky, JS Temel, ...
Annals of Oncology 22 (12), 2616-2624, 2011
The molecular pathogenesis of head and neck squamous cell carcinoma
SM Rothenberg, LW Ellisen
The Journal of clinical investigation 122 (6), 1951-1957, 2012
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