Heterozygous carriage of the alpha1-antitrypsin Pi* Z variant increases the risk to develop liver cirrhosis P Strnad, S Buch, K Hamesch, J Fischer, J Rosendahl, R Schmelz, ... Gut 68 (6), 1099-1107, 2019 | 120 | 2019 |
Liver fibrosis and metabolic alterations in adults with alpha-1-antitrypsin deficiency caused by the Pi* ZZ mutation K Hamesch, M Mandorfer, VM Pereira, LS Moeller, M Pons, GE Dolman, ... Gastroenterology 157 (3), 705-719. e18, 2019 | 103 | 2019 |
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation M Vujkovic, S Ramdas, KM Lorenz, X Guo, R Darlay, HJ Cordell, J He, ... Nature genetics 54 (6), 761-771, 2022 | 87 | 2022 |
Association of telomere length with risk of disease and mortality CV Schneider, KM Schneider, A Teumer, KL Rudolph, D Hartmann, ... JAMA internal medicine 182 (3), 291-300, 2022 | 87 | 2022 |
Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment KM Schneider, A Mohs, W Gui, EJC Galvez, LS Candels, L Hoenicke, ... Nature Communications 13 (1), 3964, 2022 | 80 | 2022 |
Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling KM Schneider, LS Candels, JR Hov, M Myllys, R Hassan, CV Schneider, ... Nature Metabolism 3 (9), 1228-1241, 2021 | 70 | 2021 |
Intestinal dysbiosis amplifies acetaminophen-induced acute liver injury KM Schneider, C Elfers, A Ghallab, CV Schneider, EJC Galvez, A Mohs, ... Cellular and Molecular Gastroenterology and Hepatology 11 (4), 909-933, 2021 | 69 | 2021 |
Liver phenotypes of European adults heterozygous or homozygous for Pi∗ Z variant of AAT (Pi∗ MZ vs Pi∗ ZZ genotype) and noncarriers CV Schneider, K Hamesch, A Gross, M Mandorfer, LS Moeller, V Pereira, ... Gastroenterology 159 (2), 534-548. e11, 2020 | 59 | 2020 |
The enteric nervous system relays psychological stress to intestinal inflammation KM Schneider, N Blank, Y Alvarez, K Thum, P Lundgren, L Litichevskiy, ... Cell 186 (13), 2823-2838. e20, 2023 | 52 | 2023 |
Alpha-1 antitrypsin deficiency: A re-surfacing adult liver disorder M Fromme, CV Schneider, C Trautwein, N Brunetti-Pierri, P Strnad Journal of Hepatology 76 (4), 946-958, 2022 | 41 | 2022 |
Physical activity is associated with reduced risk of liver disease in the prospective UK Biobank cohort CV Schneider, I Zandvakili, CA Thaiss, KM Schneider JHEP Reports 3 (3), 100263, 2021 | 37 | 2021 |
Hepatobiliary phenotypes of adults with alpha-1 antitrypsin deficiency M Fromme, CV Schneider, V Pereira, K Hamesch, M Pons, MC Reichert, ... Gut 71 (2), 415-423, 2022 | 35 | 2022 |
A genome-first approach to mortality and metabolic phenotypes in MTARC1 p. Ala165Thr (rs2642438) heterozygotes and homozygotes CV Schneider, KM Schneider, DM Conlon, J Park, M Vujkovic, I Zandvakili, ... Med 2 (7), 851-863. e3, 2021 | 25 | 2021 |
Assessment of liver phenotype in adults with severe alpha-1 antitrypsin deficiency (Pi* ZZ genotype) J Kümpers, M Fromme, CV Schneider, C Trautwein, H Denk, K Hamesch, ... Journal of Hepatology 71 (6), 1272-1274, 2019 | 22 | 2019 |
SARS-CoV-2 infection in alpha1-antitrypsin deficiency CV Schneider, P Strnad Respiratory Medicine 184, 106466, 2021 | 16 | 2021 |
A genome-wide association study for nonalcoholic fatty liver disease identifies novel genetic loci and trait-relevant candidate genes in the Million Veteran Program M Vujkovic, S Ramdas, KM Lorenz, CV Schneider, J Park, KM Lee, ... medRxiv, 2021 | 15 | 2021 |
Sortilin restricts secretion of apolipoprotein B-100 by hepatocytes under stressed but not basal conditions DM Conlon, CV Schneider, YA Ko, A Rodrigues, K Guo, NJ Hand, ... The Journal of Clinical Investigation 132 (6), 2022 | 13 | 2022 |
A new era for steatotic liver disease: Evaluating the novel nomenclature in the UK Biobank KM Schneider, CV Schneider Journal of Hepatology 80 (2), e58-e60, 2024 | 12 | 2024 |
Dietary vitamin e intake is associated with a reduced risk of developing digestive diseases and nonalcoholic fatty liver disease E Scorletti, KT Creasy, M Vujkovic, M Vell, I Zandvakili, DJ Rader, ... Official journal of the American College of Gastroenterology| ACG 117 (6 …, 2022 | 12 | 2022 |
Phenome‐wide association study in adult coeliac disease: role of HLA subtype CV Schneider, M Kleinjans, M Fromme, KM Schneider, P Strnad Alimentary Pharmacology & Therapeutics 53 (4), 510-518, 2021 | 12 | 2021 |