The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users MJ Shram, JE Henningfield, G Apseloff, CW Gorodetzky, S De Martin, ... Translational Psychiatry 13 (1), 192, 2023 | 3 | 2023 |
No meaningful opioid abuse liability of REL-1017 (esmethadone; d-methadone), a rapid-acting antidepressant in clinical development: a human abuse potential study J Henningfield, G Apseloff, C Gorodetsky, M Pappagallo, M Shram, ... Neuropsychopharmacology 46 (SUPPL 1), 241-242, 2021 | 2 | 2021 |
No Meaningful Opioid Abuse Liability of REL-1017 (esmethadone; d-methadone), a RapidActing Antidepressant in Clinical Development: A Human Abuse Potential Study. J Henningfield, G Apseloff, MS Charles Gorodetzky, Marco Pappagallo, ... NEI Annual Conference, 2022 | | 2022 |
No meaningful abuse potential in recreational ketamine users of REL-1017 (esmethadone hydrochloride), a new NMDAR antagonist and potential rapid-acting antidepressant PM Shram M, Henningfield J, Apseloff G, Gorodetzky C, De Martin S, Vocci F ... Ketamine 2022, 2022 | | 2022 |
No meaningful abuse potential in recreational ketamine users of REL-1017 (esmethadone hydrochloride), a new NMDAR antagonist and potential rapid-acting antidepressant PM Shram M, Henningfield J, Apseloff G, Gorodetzky C, De Martin S, Vocci F ... American Society of Clinical Psychopharmacology (ASCP) 2022., 2022 | | 2022 |
No meaningful abuse potential in recreational opioid users of REL-1017 (esmethadone hydrochloride), a new NMDAR antagonist and potential rapid-acting antidepressant PM Shram M, Henningfield J, Apseloff G, Gorodetzky C, De Martin S, Vocci F ... Ketamine 2022., 2022 | | 2022 |
No meaningful abuse potential in recreational opioid users of REL-1017 (esmethadone hydrochloride), a new NMDAR antagonist and potential rapid-acting antidepressant PM Shram M, Henningfield J, Apseloff G, Gorodetzky C, De Martin S, Vocci F ... American Society of Clinical Psychopharmacology (ASCP) 2022., 2022 | | 2022 |
REL-1017 (esmethadone hydrochloride), a potential rapid-acting antidepressant has no meaningful opioid abuse potential in non-clinical and clinical abuse potential studies PM Shram M, Henningfield J, Apseloff G, Gorodetzky C, De Martin S, Vocci F ... The College of Problems of Drug Dependence (CPDD) 2022., 2022 | | 2022 |