CRISPR-CasΦ from huge phages is a hypercompact genome editor P Pausch, B Al-Shayeb, E Bisom-Rapp, CA Tsuchida, Z Li, BF Cress, ... Science 369 (6501), 333-337, 2020 | 459 | 2020 |
CasX enzymes comprise a distinct family of RNA-guided genome editors JJ Liu, N Orlova, BL Oakes, E Ma, HB Spinner, KLM Baney, J Chuck, ... Nature 566 (7743), 218-223, 2019 | 441 | 2019 |
Proteingym: Large-scale benchmarks for protein fitness prediction and design P Notin, A Kollasch, D Ritter, L Van Niekerk, S Paul, H Spinner, N Rollins, ... Advances in Neural Information Processing Systems 36, 2024 | 31 | 2024 |
Agricultural Soil Management Practices Differentially Shape the Bacterial and Fungal Microbiomes of Sorghum bicolor HML Wipf, L Xu, C Gao, HB Spinner, J Taylor, P Lemaux, J Mitchell, ... Applied and environmental microbiology 87 (5), e02345-20, 2021 | 19 | 2021 |
Proteingym: Large-scale benchmarks for protein design and fitness prediction P Notin, AW Kollasch, D Ritter, L van Niekerk, S Paul, H Spinner, ... bioRxiv, 2023 | 16 | 2023 |
Removing bias in sequence models of protein fitness AY Shaw, HB Spinner, S Gurev, JE Shin, N Rollins, DS Marks bioRxiv, 2023.09. 28.560044, 2023 | 4 | 2023 |
Engineered casx systems B Oakes, S Higgins, H Spinner, S Denny, BT Staahl, K Taylor, K Baney, ... US Patent US20220220508A1, 2022 | 3 | 2022 |
Engineered Proteins AM Benjamin Oakes, Sean Higgins, Hannah Spinner, Sarah Denny, Brett T Staahl ... US Patent US20220081681A1, 2022 | 3* | 2022 |
Continuous evolution of user-defined genes at 1-million-times the genomic mutation rate G Rix, RL Williams, H Spinner, VJ Hu, DS Marks, CC Liu bioRxiv, 2023.11. 13.566922, 2023 | 2 | 2023 |
Compositions and methods for the targeting of sod1 CU Benjamin Oakes, Sean Higgins, Hannah Spinner, Sarah Denny, Brett T Staahl ... US Patent US11613742B2, 2022 | 2* | 2022 |
How well do generative protein models generate? H Spinner, AW Kollasch, DS Marks ICLR 2024 Workshop on Generative and Experimental Perspectives for …, 2024 | 1 | 2024 |
Deep generative modeling of the human proteome reveals over a hundred novel genes involved in rare genetic disorders R Orenbuch, AW Kollasch, HD Spinner, CA Shearer, TA Hopf, ... Medrxiv, 2023 | 1 | 2023 |
Compositions and methods for the targeting of pcsk9 CU Benjamin Oakes, Sean Higgins, Hannah Spinner, Sarah Denny, Brett T Staahl ... US Patent App. 17/791,130, 2023 | 1* | 2023 |
Guide Scaffolds MA Benjamin Oakes, Sean Higgins, Hannah Spinner, Sarah Denny, Brett T Staahl ... US Patent App. 18/058,251, 2023 | 1* | 2023 |
Compositions and methods for use in immunotherapy B Oakes, S Higgins, H Spinner, S Denny, BT Staahl, K Taylor, K Baney, ... US Patent US20230081117A1, 2023 | 1 | 2023 |
Compositions and methods for the targeting of htt B Oakes, S Higgins, H Spinner, S Denny, BT Staahl, K Taylor, K Baney, ... US Patent US20230032369A1, 2023 | 1 | 2023 |
Compositions and methods for the targeting of rhodopsin B Oakes, H Spinner, S Denny, BT Staahl, K Taylor, K Baney, I Colin, ... US Patent 11,535,835, 2023 | 1 | 2023 |
Deep mutational evolution of biomolecules B Oakes, S Higgins, H Spinner, K Taylor, S Denny US Patent US20220177872A1, 2022 | 1 | 2022 |
Particle delivery systems SM Jason Fernandes, Sean Higgins, Isabel Colin, Hannah Spinner, Matthew ... US Patent App. 18/164,138, 2023 | | 2023 |
Designing and Evolving Neuron-Specific Proteases H Spinner, C Hemez, J McCreary, DR Liu, DS Marks NeurIPS 2022 Workshop on Learning Meaningful Representations of Life, 2022 | | 2022 |