Negishi coupling of secondary alkylzinc halides with aryl bromides and chlorides C Han, SL Buchwald Journal of the American Chemical Society 131 (22), 7532-7533, 2009 | 307 | 2009 |
Catalytic ester− amide exchange using group (IV) metal alkoxide− activator complexes C Han, JP Lee, E Lobkovsky, JA Porco Journal of the American Chemical Society 127 (28), 10039-10044, 2005 | 211 | 2005 |
Copper-Mediated Synthesis of N-Acyl Vinylogous Carbamic Acids and Derivatives: Synthesis of the Antibiotic CJ-15,801 C Han, R Shen, S Su, JA Porco Organic Letters 6 (1), 27-30, 2004 | 182 | 2004 |
Synthesis of carbamates and ureas using Zr (IV)-catalyzed exchange processes C Han, Porco Organic letters 9 (8), 1517-1520, 2007 | 101 | 2007 |
Highly selective palladium-catalyzed cross-coupling of secondary alkylzinc reagents with heteroaryl halides Y Yang, K Niedermann, C Han, SL Buchwald Organic letters 16 (17), 4638-4641, 2014 | 91 | 2014 |
Highly stereoselective synthesis of tetrasubstituted acyclic all-carbon olefins via enol tosylation and Suzuki–Miyaura coupling BX Li, DN Le, KA Mack, A McClory, NK Lim, T Cravillion, S Savage, C Han, ... Journal of the American Chemical Society 139 (31), 10777-10783, 2017 | 79 | 2017 |
Stereoconvergent and-divergent synthesis of tetrasubstituted alkenes by nickel-catalyzed cross-couplings D Zell, C Kingston, J Jermaks, SR Smith, N Seeger, J Wassmer, LE Sirois, ... Journal of the American Chemical Society 143 (45), 19078-19090, 2021 | 50 | 2021 |
Asymmetric hydrogenation of unfunctionalized tetrasubstituted acyclic olefins R Bigler, KA Mack, J Shen, P Tosatti, C Han, S Bachmann, H Zhang, ... Angewandte Chemie 132 (7), 2866-2871, 2020 | 37 | 2020 |
Asymmetric synthesis of Akt kinase inhibitor ipatasertib C Han, S Savage, M Al-Sayah, H Yajima, T Remarchuk, R Reents, B Wirz, ... Organic letters 19 (18), 4806-4809, 2017 | 37 | 2017 |
Reaction discovery employing macrocycles: transannular cyclizations of macrocyclic bis-lactams C Han, S Rangarajan, AC Voukides, AB Beeler, R Johnson, JA Porco Jr Organic letters 11 (2), 413-416, 2009 | 25 | 2009 |
Atroposelective negishi coupling optimization guided by multivariate linear regression analysis: asymmetric synthesis of KRAS G12C covalent inhibitor GDC-6036 J Xu, S Grosslight, KA Mack, SC Nguyen, K Clagg, NK Lim, ... Journal of the American Chemical Society 144 (45), 20955-20963, 2022 | 24 | 2022 |
Chemoselective copper-catalyzed Ullmann-type coupling of oxazolidinones with bromoiodoarenes SM Kelly, C Han, L Tung, F Gosselin Organic letters 19 (11), 3021-3024, 2017 | 23 | 2017 |
Magnesium ethoxide promoted conversion of nitriles to amidines and its application in 5, 6-dihydroimidazobenzoxazepine synthesis ME Dalziel, JA Deichert, DE Carrera, D Beaudry, C Han, H Zhang, ... Organic letters 20 (9), 2624-2627, 2018 | 19 | 2018 |
Stereocontrolled synthesis of arylomycin-based gram-negative antibiotic GDC-5338 N Wong, F Petronijević, AY Hong, X Linghu, SM Kelly, H Hou, T Cravillion, ... Organic letters 21 (22), 9099-9103, 2019 | 18 | 2019 |
Palladium-catalyzed site-selective amidation of dichloroazines IS Young, AL Glass, T Cravillion, C Han, H Zhang, F Gosselin Organic letters 20 (13), 3902-3906, 2018 | 18 | 2018 |
Synthesis of PI3K inhibitor GDC-0077 via a stereocontrolled N-arylation of α-amino acids C Han, SM Kelly, T Cravillion, SJ Savage, T Nguyen, F Gosselin Tetrahedron 75 (32), 4351-4357, 2019 | 16 | 2019 |
Synthesis of Selective Estrogen Receptor Degrader GDC-0810 via Stereocontrolled Assembly of a Tetrasubstituted All-Carbon Olefin S Savage, A McClory, H Zhang, T Cravillion, NK Lim, C Masui, ... The Journal of Organic Chemistry 83 (19), 11571-11576, 2018 | 15 | 2018 |
Copper-Catalyzed Synthesis of Dibenzo [b, f] imidazo [1, 2-d][1, 4] oxazepine Derivatives via a Double Ullmann Coupling Reaction XY Chen, ZH Li, JQ Liu, XS Wang Synthesis 51 (07), 1662-1668, 2019 | 13 | 2019 |
Highly Regioselective and Practical Synthesis of 5-Bromo-4-chloro-3-nitro-7-azaindole C Han, K Green, E Pfeifer, F Gosselin Organic Process Research & Development 21 (4), 664-668, 2017 | 13 | 2017 |
Process for making hydroxylated cyclopentylpyrimidine compounds D Askin, C Han, JW Lane, T Remarchuk, S Shakya, CG Sowell, ... US Patent 9,416,110, 2016 | 13 | 2016 |