| Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand … J Huang, D Liu, Y Wang, L Liu, J Li, J Yuan, Z Jiang, Z Jiang, WLW Hsiao, ... Gut 71 (4), 734-745, 2022 | 216 | 2022 |
| Early lung cancer diagnostic biomarker discovery by machine learning methods Y Xie, WY Meng, RZ Li, YW Wang, X Qian, C Chan, ZF Yu, XX Fan, ... Translational oncology 14 (1), 100907, 2021 | 167 | 2021 |
| Cordycepin inhibits drug-resistance non-small cell lung cancer progression by activating AMPK signaling pathway C Wei, X Yao, Z Jiang, Y Wang, D Zhang, X Chen, X Fan, C Xie, J Cheng, ... Pharmacological research 144, 79-89, 2019 | 66 | 2019 |
| Identification of a novel protein arginine methyltransferase 5 inhibitor in non-small cell lung cancer by structure-based virtual screening Q Wang, J Xu, Y Li, J Huang, Z Jiang, Y Wang, L Liu, ELH Leung, X Yao Frontiers in pharmacology 9, 173, 2018 | 46 | 2018 |
| Identification of a new potent inhibitor targeting KRAS in non-small cell lung cancer cells C Xie, Y Li, LL Li, XX Fan, YW Wang, CL Wei, L Liu, ELH Leung, XJ Yao Frontiers in pharmacology 8, 823, 2017 | 45 | 2017 |
| Selective inhibition mechanism of RVX-208 to the second bromodomain of bromo and extraterminal proteins: insight from microsecond molecular dynamics simulations Q Wang, Y Li, J Xu, Y Wang, ELH Leung, L Liu, X Yao Scientific reports 7 (1), 8857, 2017 | 34 | 2017 |
| Recent advances of IDH1 mutant inhibitor in cancer therapy W Tian, W Zhang, Y Wang, R Jin, Y Wang, H Guo, Y Tang, X Yao Frontiers in pharmacology 13, 982424, 2022 | 27 | 2022 |
| Identification of potential genetic causal variants for rheumatoid arthritis by whole-exome sequencing Y Li, ELH Leung, H Pan, X Yao, Q Huang, M Wu, T Xu, Y Wang, J Cai, ... Oncotarget 8 (67), 111119, 2017 | 25 | 2017 |
| Chelidonine selectively inhibits the growth of gefitinib-resistant non-small cell lung cancer cells through the EGFR-AMPK pathway YJ Xie, WN Gao, QB Wu, XJ Yao, ZB Jiang, YW Wang, WJ Wang, W Li, ... Pharmacological Research 159, 104934, 2020 | 24 | 2020 |
| Krukovine suppresses KRAS-mutated lung cancer cell growth and proliferation by inhibiting the RAF-ERK pathway and inactivating AKT pathway H Lai, Y Wang, F Duan, Y Li, Z Jiang, L Luo, L Liu, ELH Leung, X Yao Frontiers in pharmacology 9, 958, 2018 | 22 | 2018 |
| Identification of a new pyruvate kinase M2 isoform (PKM 2) activator for the treatment of non‐small‐cell lung cancer (NSCLC) RZ Li, XX Fan, DF Shi, GY Zhu, YW Wang, LX Luo, HD Pan, XJ Yao, ... Chemical biology & drug design 92 (5), 1851-1858, 2018 | 20 | 2018 |
| Gossypol Inhibits Non-small Cell Lung Cancer Cells Proliferation by Targeting EGFRL858R/T790M Y Wang, H Lai, X Fan, L Luo, F Duan, Z Jiang, Q Wang, ELH Leung, L Liu, ... Frontiers in Pharmacology 9, 728, 2018 | 20 | 2018 |
| Discovery of a new inhibitor targeting PD-L1 for cancer immunotherapy F Wang, W Ye, S Wang, Y He, H Zhong, Y Wang, Y Zhu, J Han, Z Bing, ... Neoplasia 23 (3), 281-293, 2021 | 19 | 2021 |
| Discovery of novel IDH1 inhibitor through comparative structure-based virtual screening Y Wang, S Tang, H Lai, R Jin, X Long, N Li, Y Tang, H Guo, X Yao, ... Frontiers in Pharmacology 11, 579768, 2020 | 19 | 2020 |
| Potential prognostic factors in progression-free survival for patients with cervical cancer HH Chen, WY Meng, RZ Li, QY Wang, YW Wang, HD Pan, PY Yan, ... BMC cancer 21 (1), 531, 2021 | 18 | 2021 |
| Computational study on the selective inhibition mechanism of MS402 to the first and second bromodomains of BRD4 Q Wang, Y Li, J Xu, Y Wang, D Shi, L Liu, ELH Leung, X Yao Proteins: Structure, Function, and Bioinformatics 87 (1), 3-11, 2019 | 18 | 2019 |
| Classical molecular dynamics and metadynamics simulations decipher the mechanism of CBP30 selectively inhibiting CBP/p300 bromodomains Q Wang, X An, J Xu, Y Wang, L Liu, ELH Leung, X Yao Organic & Biomolecular Chemistry 16 (35), 6521-6530, 2018 | 17 | 2018 |
| The folding mechanism and key metastable state identification of the PrP127–147 monomer studied by molecular dynamics simulations and Markov state model analysis S Zhou, Q Wang, Y Wang, X Yao, W Han, H Liu Physical Chemistry Chemical Physics 19 (18), 11249-11259, 2017 | 17 | 2017 |
| Discovery of icotinib-1, 2, 3-triazole derivatives as IDO1 inhibitors L Mao, Y Wang, J Zhao, G Xu, X Yao, YM Li Frontiers in pharmacology 11, 579024, 2020 | 15 | 2020 |
| Descriptor selection via log-sum regularization for the biological activities of chemical structure LY Xia, YW Wang, DY Meng, XJ Yao, H Chai, Y Liang International journal of molecular sciences 19 (1), 30, 2017 | 13 | 2017 |
Elaine Lai-Han LeungUniversity of MacauVerified email at um.edu.mo
