Astrid M. van der Sar
Astrid M. van der Sar
Roche Netherlands B.V., Woerden, The Netherlands
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Towards a new combination therapy for tuberculosis with next generation benzothiazinones
V Makarov, B Lechartier, M Zhang, J Neres, AM van der Sar, SA Raadsen, ...
EMBO molecular medicine 6 (3), 372-383, 2014
Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections
AM Van Der Sar, RJP Musters, FJM Van Eeden, BJ Appelmelk, ...
Cellular microbiology 5 (9), 601-611, 2003
Infection of zebrafish embryos with intracellular bacterial pathogens
EL Benard, AM van der Sar, F Ellett, GJ Lieschke, HP Spaink, AH Meijer
JoVE (Journal of Visualized Experiments), e3781, 2012
A star with stripes: zebrafish as an infection model
AM van der Sar, BJ Appelmelk, CMJE Vandenbroucke-Grauls, W Bitter
Trends in microbiology 12 (10), 451-457, 2004
MyD88 innate immune function in a zebrafish embryo infection model
AM van der Sar, OW Stockhammer, C van der Laan, HP Spaink, W Bitter, ...
Infection and immunity 74 (4), 2436-2441, 2006
Zebrafish development and regeneration: new tools for biomedical research
SA Brittijn, SJ Duivesteijn, M Belmamoune, LFM Bertens, W Bitter, ...
International Journal of Developmental Biology 53 (5-6), 835-850, 2009
Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation
AM Abdallah, J Bestebroer, NDL Savage, K De Punder, M Van Zon, ...
The Journal of Immunology 187 (9), 4744-4753, 2011
Mycobacterium marinum Strains Can Be Divided into Two Distinct Types Based on Genetic Diversity and Virulence
AM Van Der Sar, AM Abdallah, M Sparrius, E Reinders, ...
Infection and immunity 72 (11), 6306-6312, 2004
Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection
AH Meijer, FJ Verbeek, E Salas-Vidal, M Corredor-Adámez, J Bussman, ...
Molecular Immunology 42 (10), 1185-1203, 2005
Identification and real-time imaging of a myc-expressing neutrophil population involved in inflammation and mycobacterial granuloma formation in zebrafish
AH Meijer, AM van der Sar, C Cunha, GEM Lamers, MA Laplante, ...
Developmental & Comparative Immunology 32 (1), 36-49, 2008
Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component
EJM Stoop, T Schipper, SK Rosendahl Huber, AE Nezhinsky, FJ Verbeek, ...
Disease models & mechanisms 4 (4), 526-536, 2011
The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium–host interaction
BJ Appelmelk, J Den Dunnen, NN Driessen, R Ummels, M Pak, J Nigou, ...
Cellular microbiology 10 (4), 930-944, 2008
Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components
AM van der Sar, HP Spaink, A Zakrzewska, W Bitter, AH Meijer
Molecular immunology 46 (11-12), 2317-2332, 2009
The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection
V Torraca, C Cui, R Boland, JP Bebelman, AM van der Sar, MJ Smit, ...
Disease models & mechanisms 8 (3), 253-269, 2015
The role of gamma interferon in innate immunity in the zebrafish embryo
D Sieger, C Stein, D Neifer, AM van der Sar, M Leptin
Disease models & mechanisms 2 (11-12), 571-581, 2009
Tubercle bacilli rely on a type VII army for pathogenicity
EJM Stoop, W Bitter, AM van der Sar
Trends in microbiology 20 (10), 477-484, 2012
A Novel Extracytoplasmic Function (ECF) Sigma Factor Regulates Virulence in Pseudomonas aeruginosa
MA Llamas, A van der Sar, BCH Chu, M Sparrius, HJ Vogel, W Bitter
PLoS pathogens 5 (9), e1000572, 2009
First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio)
S Yoon, S Mitra, C Wyse, A Alnabulsi, J Zou, EM Weerdenburg, ...
PloS one 10 (6), e0126378, 2015
ESX‐5‐deficient Mycobacterium marinum is hypervirulent in adult zebrafish
EM Weerdenburg, AM Abdallah, S Mitra, K De Punder, NN Van Der Wel, ...
Cellular microbiology 14 (5), 728-739, 2012
Genome-wide transposon mutagenesis indicates that Mycobacterium marinum customizes its virulence mechanisms for survival and replication in different hosts
EM Weerdenburg, AM Abdallah, F Rangkuti, M Abd El Ghany, TD Otto, ...
Infection and immunity 83 (5), 1778-1788, 2015
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