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Tommi Mäklin
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Themisto: a scalable colored k-mer index for sensitive pseudoalignment against hundreds of thousands of bacterial genomes
JN Alanko, J Vuohtoniemi, T Mäklin, SJ Puglisi
Bioinformatics 39 (Supplement_1), i260–i269, 2023
442023
Strong pathogen competition in neonatal gut colonisation
T Mäklin, HA Thorpe, AK Pöntinen, RA Gladstone, Y Shao, A McNally, ...
Nature Communications 13 (7417), 2022
382022
Bacterial genomic epidemiology with mixed samples
T Mäklin, T Kallonen, J Alanko, Ø Samuelsen, K Hegstad, V Mäkinen, ...
Microbial Genomics 7 (11), 000691, 2021
36*2021
High-resolution sweep metagenomics using fast probabilistic inference
T Mäklin, T Kallonen, S David, CJ Boinett, B Pascoe, G Méric, ...
Wellcome open research, 2021
332021
Genomic and phenotypic characterization of Clostridium botulinum isolates from an infant botulism case suggests adaptation signatures to the gut
FP Douillard, Y Derman, C Woudstra, K Selby, T Mäklin, MB Dorner, ...
MBio 13 (3), e02384-21, 2022
112022
Seamless, rapid, and accurate analyses of outbreak genomic data using split k-mer analysis
R Derelle, J von Wachsmann, T Mäklin, J Hellewell, T Russell, A Lalvani, ...
Genome research 34 (10), 1661-1673, 2024
72024
Deep sequencing of Escherichia coli exposes colonisation diversity and impact of antibiotics in Punjab, Pakistan
T Khawaja, T Mäklin, T Kallonen, RA Gladstone, AK Pöntinen, S Mero, ...
Nature Communications 15 (1), 5196, 2024
42024
Closing Clostridium botulinum Group III Genomes Using Long-Read Sequencing
C Woudstra, T Mäklin, Y Derman, L Bano, H Skarin, C Mazuet, A Honkela, ...
Microbiology resource announcements 10 (22), 10.1128/mra. 01364-20, 2021
42021
Enhanced metagenomics-enabled transmission inference with TRACS
G Tonkin-Hill, Y Shao, AE Zarebski, S Mallawaarachchi, O Xie, T Mäklin, ...
bioRxiv, 2024.08. 19.608527, 2024
22024
Geographical variation in the incidence of colorectal cancer and urinary tract cancer is associated with population exposure to colibactin-producing Escherichia coli
T Mäklin, A Taira, S Arredondo-Alonso, Y Shao, MR Stratton, TD Lawley, ...
The Lancet Microbe, 2024
12024
Group 2 and 3 ABC-transporter dependant capsular K-loci contribute significantly to variation in the invasive potential of Escherichia coli
RA Gladstone, M Pesonen, AK Pöntinen, T Mäklin, N MacAlasdair, ...
medRxiv, 2024.11. 22.24317484, 2024
12024
A Novel Prophage-like Insertion Element within yabG Triggers Early Entry into Sporulation in Clostridium botulinum
FP Douillard, IM Portinha, Y Derman, C Woudstra, T Mäklin, MB Dorner, ...
Viruses 15 (12), 2431, 2023
12023
Probabilistic Methods for High-Resolution Metagenomics
T Mäklin
Doctoral dissertation, University of Helsinki, 2022
12022
Pan-pathogen deep sequencing of nosocomial bacterial pathogens in Italy in spring 2020: a prospective cohort study
HA Thorpe, M Pesonen, M Corbella, H Pesonen, S Gaiarsa, CJ Boinett, ...
The Lancet Microbe 5 (10), 2024
2024
Exploring the pediatric nasopharyngeal bacterial microbiota with culture-based MALDI-TOF mass spectrometry and targeted metagenomic sequencing
S Pol, T Kallonen, T Mäklin, P Sar, J Hopkins, S Soeng, T Miliya, CL Ling, ...
Mbio 15 (6), e00784-24, 2024
2024
Basic reproduction number for pandemic Escherichia coli clones is comparable to typical pandemic viruses
F Ojala, H Pesonen, RA Gladstone, T Mäklin, G Tonkin-Hill, P Marttinen, ...
bioRxiv, 2024.05. 08.593267, 2024
2024
A longitudinal genomic and functional analysis of Clostridium botulinum isolated from an infant botulism case
FP Douillard, Y Derman, C Woudstra, K Selby, T Mäklin, A Honkela, ...
Toxicon 190, S17-S17, 2021
2021
Identifying Bacterial Strains from Sequencing Data
T Mäklin, J Corander, A Honkela
Data Mining for Systems Biology: Methods and Protocols, 1-7, 2018
2018
Probabilistic quantification of bacterial strain mixtures
T Mäklin
Master's thesis, University of Helsinki, 2017
2017
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Articles 1–19