Rigidly connected multispecific artificial binders with adjustable geometries Y Wu, A Batyuk, A Honegger, F Brandl, PRE Mittl, A Plückthun Scientific reports 7 (1), 11217, 2017 | 37 | 2017 |
DARPin-based crystallization chaperones exploit molecular geometry as a screening dimension in protein crystallography A Batyuk, Y Wu, A Honegger, MM Heberling, A Plückthun Journal of molecular biology 428 (8), 1574-1588, 2016 | 36 | 2016 |
Dipeptidyl Aminopeptidase IV from Stenotrophomonas maltophilia Exhibits Activity against a Substrate Containing a 4-Hydroxyproline Residue Y Nakajima, K Ito, T Toshima, T Egawa, H Zheng, H Oyama, YF Wu, ... Journal of bacteriology 190 (23), 7819-7829, 2008 | 28 | 2008 |
Generation of fluorogen-activating designed ankyrin repeat proteins (FADAs) as versatile sensor tools M Schütz, A Batyuk, C Klenk, L Kummer, S De Picciotto, B Gülbakan, ... Journal of molecular biology 428 (6), 1272-1289, 2016 | 26 | 2016 |
Structural basis for the selective inhibition of c-Jun N-terminal kinase 1 determined by rigid DARPin–DARPin fusions Y Wu, A Honegger, A Batyuk, PRE Mittl, A Plückthun Journal of molecular biology 430 (14), 2128-2138, 2018 | 15 | 2018 |
Crystal structure of a heterotetrameric katanin p60: p80 complex L Faltova, K Jiang, D Frey, Y Wu, G Capitani, AE Prota, A Akhmanova, ... Structure 27 (9), 1375-1383. e3, 2019 | 12 | 2019 |
Rigidity of the extracellular part of HER2: Evidence from engineering subdomain interfaces and shared‐helix DARPin‐DARPin fusions C Jost, JC Stüber, A Honegger, Y Wu, A Batyuk, A Plückthun Protein Science 26 (9), 1796-1806, 2017 | 11 | 2017 |
Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase K Yamashita, Y Nakajima, H Matsushita, Y Nishiya, R Yamazawa, Y Wu, ... Journal of molecular biology 396 (4), 1081-1096, 2010 | 11 | 2010 |
Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization N Friedrich, E Stiegeler, M Glögl, T Lemmin, S Hansen, C Kadelka, Y Wu, ... Nature Communications 12 (1), 6705, 2021 | 9 | 2021 |
Crystal structure of the catalytic domain of botulinum neurotoxin subtype A3 O Leka, Y Wu, X Li, RA Kammerer Journal of Biological Chemistry 296, 2021 | 7 | 2021 |
A DARPin promotes faster onset of botulinum neurotoxin A1 action O Leka, Y Wu, G Zanetti, S Furler, T Reinberg, J Marinho, JV Schaefer, ... Nature Communications 14 (1), 8317, 2023 | 1 | 2023 |
A DARPin Increases the Catalytic Activity of Botulinum Neurotoxin A1 O Leka, Y Wu, G Zanetti, S Furler, T Reinberg, J Marinho, J Schaefer, ... | | 2023 |
Adapting DARPin-based Rigid Fusions for Crystallography Y Wu University of Zurich, 2017 | | 2017 |
Design and application of crystallization aids comprising DARPin domains. P Mittl, Y Wu, P Ernst, A Batyuk, A Honegger, A Pluckthun Acta Crystallographica Section A: Foundations and Advances 73, C1086-C1086, 2017 | | 2017 |
Neutralization of Diverse HIV Strains by V3 Specific DARPins with Different Structural Preferences in Epitope Recognition N Friedrich, A Mann, E Stiegeler, Y Wu, A Batyuk, P Rusert, J Weber, ... AIDS RESEARCH AND HUMAN RETROVIRUSES 29 (11), A109-A109, 2013 | | 2013 |
Engineering novel crystallization chaperones with tunable crystal packing and increased power of phasing A Batyuk, Y Wu, A Honegger, A Plueckthun FEBS JOURNAL 280, 604-605, 2013 | | 2013 |
Supplementary Information for A Batyuk, Y Wu, A Honegger, MM Heberling, A Plückthun | | |