| Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction W Qi, HA Keenan, Q Li, A Ishikado, A Kannt, T Sadowski, MA Yorek, ... Nature medicine 23 (6), 753-762, 2017 | 384 | 2017 |
| Diabetes distress: understanding the hidden struggles of living with diabetes and exploring intervention strategies E Berry, S Lockhart, M Davies, JR Lindsay, M Dempster Postgraduate medical journal 91 (1075), 278-283, 2015 | 141 | 2015 |
| GDF15: a hormone conveying somatic distress to the brain SM Lockhart, V Saudek, S O’Rahilly Endocrine reviews 41 (4), 610-642, 2020 | 139 | 2020 |
| Endothelial insulin receptors differentially control insulin signaling kinetics in peripheral tissues and brain of mice M Konishi, M Sakaguchi, SM Lockhart, W Cai, ME Li, EP Homan, ... Proceedings of the National Academy of Sciences 114 (40), E8478-E8487, 2017 | 122 | 2017 |
| When two pandemics meet: why is obesity associated with increased COVID-19 mortality? SM Lockhart, S O’Rahilly Med 1 (1), 33-42, 2020 | 104 | 2020 |
| Exendin-4 protects against post-myocardial infarction remodelling via specific actions on inflammation and the extracellular matrix E Robinson, RS Cassidy, M Tate, Y Zhao, S Lockhart, D Calderwood, ... Basic research in cardiology 110, 1-15, 2015 | 80 | 2015 |
| Diabetes distress, illness perceptions and glycaemic control in adults with type 2 diabetes K Martinez, S Lockhart, M Davies, JR Lindsay, M Dempster Psychology, Health & Medicine 23 (2), 171-177, 2018 | 60 | 2018 |
| Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15 I Cimino, H Kim, YCL Tung, K Pedersen, D Rimmington, JA Tadross, ... Proceedings of the National Academy of Sciences 118 (27), e2106868118, 2021 | 50 | 2021 |
| Insulin resistance in vascular endothelial cells promotes intestinal tumour formation X Wang, MF Häring, T Rathjen, SM Lockhart, D Sørensen, S Ussar, ... Oncogene 36 (35), 4987-4996, 2017 | 37 | 2017 |
| Circulating adipokines are associated with pre-eclampsia in women with type 1 diabetes CB Kelly, MB Hookham, JY Yu, SM Lockhart, M Du, AJ Jenkins, ... Diabetologia 60, 2514-2524, 2017 | 33 | 2017 |
| Metabolically-inactive glucagon-like peptide-1 (9–36) amide confers selective protective actions against post-myocardial infarction remodelling E Robinson, M Tate, S Lockhart, C McPeake, KM O’Neill, KS Edgar, ... Cardiovascular diabetology 15, 1-11, 2016 | 32 | 2016 |
| GDF15 linked to maternal risk of nausea and vomiting during pregnancy M Fejzo, N Rocha, I Cimino, SM Lockhart, CJ Petry, RG Kay, K Burling, ... Nature 625 (7996), 760-767, 2024 | 28 | 2024 |
| Damaging missense variants in IGF1R implicate a role for IGF-1 resistance in the etiology of type 2 diabetes EJ Gardner, KA Kentistou, S Stankovic, S Lockhart, E Wheeler, FR Day, ... Cell genomics 2 (12), 2022 | 25 | 2022 |
| SHP-1 activation inhibits vascular smooth muscle cell proliferation and intimal hyperplasia in a rodent model of insulin resistance and diabetes W Qi, Q Li, CW Liew, C Rask-Madsen, SM Lockhart, LM Rasmussen, ... Diabetologia 60, 585-596, 2017 | 24 | 2017 |
| Insulin downregulates the transcriptional coregulator CITED2, an inhibitor of proangiogenic function in endothelial cells X Wang, SM Lockhart, T Rathjen, H Albadawi, D Sørensen, BT O'neill, ... Diabetes 65 (12), 3680-3690, 2016 | 21 | 2016 |
| ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study D Gill, M Arvanitis, P Carter, AI Hernández Cordero, B Jo, V Karhunen, ... Royal Society Open Science 7 (11), 200958, 2020 | 19 | 2020 |
| Proteogenomic links to human metabolic diseases M Koprulu, J Carrasco-Zanini, E Wheeler, S Lockhart, ND Kerrison, ... Nature metabolism 5 (3), 516-528, 2023 | 12 | 2023 |
| The excess insulin requirement in severe COVID‐19 compared to non‐COVID‐19 viral pneumonitis is related to the severity of respiratory failure and pre‐existing diabetes SM Lockhart, H Griffiths, B Petrisor, A Usman, J Calvo‐Latorre, L Heales, ... Endocrinology, Diabetes & Metabolism 4 (3), e00228, 2021 | 9 | 2021 |
| Colchicine—an old dog with new tricks SM Lockhart, S O’Rahilly Nature Metabolism 3 (4), 451-452, 2021 | 8 | 2021 |
| Endothelial cell insulin signaling regulates CXCR4 (CXC motif chemokine receptor 4) and limits leukocyte adhesion to endothelium T Rathjen, B Kunkemoeller, CT Cederquist, X Wang, SM Lockhart, ... Arteriosclerosis, thrombosis, and vascular biology 42 (7), e217-e227, 2022 | 6 | 2022 |
sir stephen o'rahillyuniversity of cambridgeVerified email at medschl.cam.ac.uk
