RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8+ T cells P Duewell, A Steger, H Lohr, H Bourhis, H Hoelz, SV Kirchleitner, ... Cell Death & Differentiation 21 (12), 1825-1837, 2014 | 198 | 2014 |
Targeted activation of melanoma differentiation-associated protein 5 (MDA5) for immunotherapy of pancreatic carcinoma P Duewell, E Beller, SV Kirchleitner, T Adunka, H Bourhis, J Siveke, ... Oncoimmunology 4 (10), e1029698, 2015 | 62 | 2015 |
Glioblastoma exhibits inter-individual heterogeneity of TSPO and LAT1 expression in neoplastic and parenchymal cells L Cai, SV Kirchleitner, D Zhao, M Li, JC Tonn, R Glass, RE Kälin International Journal of Molecular Sciences 21 (2), 612, 2020 | 34 | 2020 |
Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer P Metzger, SV Kirchleitner, M Kluge, LM Koenig, C Hörth, ... Journal for immunotherapy of cancer 7, 1-16, 2019 | 33 | 2019 |
Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model P Metzger, SV Kirchleitner, DFR Boehmer, C Hörth, A Eisele, S Ormanns, ... Cancer Immunology, Immunotherapy 69 (10), 2101-2112, 2020 | 18 | 2020 |
Dying cells expose a nuclear antigen cross-reacting with anti-PD-1 monoclonal antibodies P Metzger, SV Kirchleitner, LM Koenig, C Hörth, S Kobold, S Endres, ... Scientific reports 8 (1), 8810, 2018 | 16 | 2018 |
TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression RE Kälin, L Cai, Y Li, D Zhao, H Zhang, J Cheng, W Zhang, Y Wu, ... Cell systems 12 (3), 248-262. e7, 2021 | 13 | 2021 |
TSPO PET signal using [18F]GE180 is associated with survival in recurrent gliomas S Quach, A Holzgreve, L Kaiser, M Unterrainer, FJ Dekorsy, DV Nelwan, ... European Journal of Nuclear Medicine and Molecular Imaging 50 (3), 859-869, 2023 | 12 | 2023 |
Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution LM Bartos, SV Kirchleitner, ZI Kolabas, S Quach, A Beck, J Lorenz, ... Science Advances 9 (43), eadi8986, 2023 | 5 | 2023 |
Translocator protein (18kDA)(TSPO) marks mesenchymal glioblastoma cell populations characterized by elevated numbers of tumor-associated macrophages L Weidner, J Lorenz, S Quach, FK Braun, T Rothhammer-Hampl, ... Acta Neuropathologica Communications 11 (1), 147, 2023 | 5 | 2023 |
18 kDa translocator protein positron emission tomography facilitates early and robust tumor detection in the immunocompetent SB28 glioblastoma mouse model LM Bartos, SV Kirchleitner, J Blobner, K Wind, LH Kunze, A Holzgreve, ... Frontiers in Medicine 9, 992993, 2022 | 5 | 2022 |
Cell sorting after tracer injection for precise determination of various TSPO-PET signal sources in experimental orthotopic glioblastoma L Bartos, S Kirchleitner, J Blobner, K Wind, A Holzgreve, L Gold, ... Journal of Nuclear Medicine 63 (supplement 2), 2318-2318, 2022 | 1 | 2022 |
TSPO PET Signal is Associated with Survival in Recurrent Gliomas S Quach, A Holzgreve, L Kaiser, M Unterrainer, FJ Dekorsy, DV Nelwan, ... | 1 | 2022 |
Activation of MDA5 improves anti-tumor therapy and reduces suppressive capacity of myeloid-derived suppressor cells P Metzger, SV Kirchleitner, M Kluge, LM König, S Endres, CC Friedel, ... Proceedings on Cancer-Immuno-Oncology 1 (1), on Cancer-2018• Article ID …, 2018 | 1 | 2018 |
Die Immuntherapie des Pankreaskarzinoms mit Liganden von RIG-I-like Helikasen induziert eine funktionelle Umprogrammierung von myeloiden Suppressor-Zellen mit reduzierter … SV Kirchleitner, E Schrom, S Endres, P Düwell, M Schnurr Zeitschrift für Gastroenterologie 52 (08), KG162, 2014 | 1 | 2014 |
Perifocal edema is a risk factor for preoperative seizures in patients with meningioma WHO grade 2 and 3 N Teske, NC Teske, T Greve, P Karschnia, SV Kirchleitner, PN Harter, ... Acta Neurochirurgica 166 (1), 1-11, 2024 | | 2024 |
Remote Neuroinflammation in Newly Diagnosed Glioblastoma Correlates with Unfavorable Clinical Outcome LM Bartos, S Quach, V Zenatti, SV Kirchleitner, J Blobner, K Wind-Mark, ... medRxiv, 2024.04. 23.24305825, 2024 | | 2024 |
Vergleich zweier immunsupprimierter Mausmodelle bezüglich des Imaging Phänotyps eines murinen Glioblastoms H Park, L Hörmann, LH Kunze, SV Kirchleitner, KJ Müller, ... Nuklearmedizin-NuclearMedicine 63 (02), V12, 2024 | | 2024 |
Multimodale Radiomics-Analysen zur Überlebensvorhersage bei erstdiagnostizierten Glioblastomen L Kaiser, S Quach, AJ Zounek, A Zatcepin, A Holzgreve, S Kirchleitner, ... Nuklearmedizin-NuclearMedicine 63 (02), P70, 2024 | | 2024 |
The Traumatic Inoculation Process Affects TSPO Radioligand Uptake in Experimental Orthotopic Glioblastoma L Gold, E Barci, M Brendel, M Orth, J Cheng, SV Kirchleitner, LM Bartos, ... Biomedicines 12 (1), 188, 2024 | | 2024 |