Targeting metabotropic glutamate receptors for novel treatments of schizophrenia J Maksymetz, SP Moran, PJ Conn Molecular brain 10, 1-19, 2017 | 139 | 2017 |
Induction and expression of fear sensitization caused by acute traumatic stress JN Perusini, EM Meyer, VA Long, V Rau, N Nocera, J Avershal, ... Neuropsychopharmacology 41 (1), 45-57, 2016 | 115 | 2016 |
Targeting muscarinic acetylcholine receptors for the treatment of psychiatric and neurological disorders SP Moran, J Maksymetz, PJ Conn Trends in pharmacological sciences 40 (12), 1006-1020, 2019 | 101 | 2019 |
M 1-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition SP Moran, JW Dickerson, HP Cho, Z Xiang, J Maksymetz, DH Remke, ... Neuropsychopharmacology 43 (8), 1763-1771, 2018 | 69 | 2018 |
mGlu2 and mGlu3 negative allosteric modulators divergently enhance thalamocortical transmission and exert rapid antidepressant-like effects ME Joffe, CI Santiago, KH Oliver, J Maksymetz, NA Harris, JL Engers, ... Neuron 105 (1), 46-59. e3, 2020 | 66 | 2020 |
A Novel M1 PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity JM Rook, JL Bertron, HP Cho, PM Garcia-Barrantes, SP Moran, ... ACS chemical neuroscience 9 (9), 2274-2285, 2018 | 54 | 2018 |
Mechanisms underlying prelimbic prefrontal cortex mGlu3/mGlu5-dependent plasticity and reversal learning deficits following acute stress ME Joffe, CI Santiago, BJ Stansley, J Maksymetz, RG Gogliotti, JL Engers, ... Neuropharmacology 144, 19-28, 2019 | 53 | 2019 |
Cross-species transcriptomic atlas of dorsal root ganglia reveals species-specific programs for sensory function M Jung, M Dourado, J Maksymetz, A Jacobson, BI Laufer, M Baca, ... Nature Communications 14 (1), 366, 2023 | 45 | 2023 |
Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons ME Joffe, J Maksymetz, JR Luschinger, S Dogra, AS Ferranti, DJ Luessen, ... Neuron 110 (6), 1068-1083. e5, 2022 | 39 | 2022 |
M1 Muscarinic Receptors Modulate Fear-Related Inputs to the Prefrontal Cortex: Implications for Novel Treatments of Posttraumatic Stress Disorder J Maksymetz, ME Joffe, SP Moran, BJ Stansley, B Li, K Temple, ... Biological psychiatry 85 (12), 989-1000, 2019 | 32 | 2019 |
PF-06827443 displays robust allosteric agonist and positive allosteric modulator activity in high receptor reserve and native systems SP Moran, HP Cho, J Maksymetz, DH Remke, RM Hanson, ... ACS chemical neuroscience 9 (9), 2218-2224, 2018 | 25 | 2018 |
mGlu1 potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits J Maksymetz, NE Byun, DJ Luessen, B Li, RL Barry, JC Gore, ... Cell Reports 37 (5), 109950, 2021 | 21 | 2021 |
mGlu5 Positive Allosteric Modulators Facilitate Long-Term Potentiation via Disinhibition Mediated by mGlu5-Endocannabinoid Signaling Z Xiang, X Lv, J Maksymetz, BJ Stansley, A Ghoshal, RG Gogliotti, ... ACS pharmacology & translational science 2 (3), 198-209, 2019 | 20 | 2019 |
Biased M1 receptor–positive allosteric modulators reveal role of phospholipase D in M1-dependent rodent cortical plasticity SP Moran, Z Xiang, CA Doyle, J Maksymetz, X Lv, S Faltin, NM Fisher, ... Science signaling 12 (610), eaax2057, 2019 | 12 | 2019 |
Nav1. 7 is essential for nociceptor action potentials in the mouse in a manner independent of endogenous opioids L Deng, M Dourado, RM Reese, K Huang, SD Shields, KL Stark, ... Neuron 111 (17), 2642-2659. e13, 2023 | 10 | 2023 |
Human motor neurons are rare and can be transcriptomically divided into known subtypes O Gautier, JA Blum, J Maksymetz, D Chen, C Schweingruber, I Mei, ... bioRxiv, 2023.04. 05.535689, 2023 | 5 | 2023 |
Challenges of profiling motor neuron transcriptomes from human spinal cord O Gautier, JA Blum, J Maksymetz, D Chen, C Schweingruber, I Mei, ... Neuron 111 (23), 3739-3741, 2023 | 2 | 2023 |
High-resolution cross-species transcriptomic atlas of dorsal root ganglia reveals species-specific programs for sensory function M Jung, M Dourado, J Maksymetz, A Jacobson, M Baca, O Foreman, ... bioRxiv, 2022.06. 21.497049, 2022 | 1 | 2022 |
mGlu Receptor Modulation in Murine Models of Stress and Affective Disorders J Maksymetz, ME Joffe Metabotropic Glutamate Receptor Technologies, 259-296, 2021 | 1 | 2021 |
Biased M1 positive allosteric modulators reveal novel role of phospholipase D in M1-dependent rodent cortical plasticity SP Moran, Z Xiang, CA Doyle, J Maksymetz, X Lv, S Faltin, CM Niswender, ... bioRxiv, 806943, 2019 | 1 | 2019 |