Sox2 requirement in sonic hedgehog-associated medulloblastoma J Ahlfeld, R Favaro, P Pagella, HA Kretzschmar, S Nicolis, U Schüller Cancer research 73 (12), 3796-3807, 2013 | 83 | 2013 |
Severe alterations of cerebellar cortical development after constitutive activation of Wnt signaling in granule neuron precursors A Lorenz, M Deutschmann, J Ahlfeld, C Prix, A Koch, R Smits, R Fodde, ... Molecular and cellular biology, 2011 | 73 | 2011 |
Arsenic trioxide inhibits tumor cell growth in malignant rhabdoid tumors in vitro and in vivo by targeting overexpressed Gli1 K Kerl, N Moreno, T Holsten, J Ahlfeld, J Mertins, M Hotfilder, M Kool, ... International journal of cancer 135 (4), 989-995, 2014 | 58 | 2014 |
Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton A Müller-Deku, JCM Meiring, K Loy, Y Kraus, C Heise, R Bingham, ... Nature communications 11 (1), 4640, 2020 | 57 | 2020 |
Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex J Ahlfeld, S Filser, F Schmidt, AK Wefers, DJ Merk, R Glaß, J Herms, ... Scientific reports 7 (1), 6137, 2017 | 54 | 2017 |
RIG-I-based immunotherapy enhances survival in preclinical AML models and sensitizes AML cells to checkpoint blockade M Ruzicka, LM Koenig, S Formisano, DFR Boehmer, B Vick, EM Heuer, ... Leukemia 34 (4), 1017-1026, 2020 | 50 | 2020 |
Loss of Smarc proteins impairs cerebellar development N Moreno, C Schmidt, J Ahlfeld, J Pöschl, S Dittmar, SM Pfister, M Kool, ... Journal of Neuroscience 34 (40), 13486-13491, 2014 | 48 | 2014 |
Opposing effects of CREBBP mutations govern the phenotype of Rubinstein-Taybi syndrome and adult SHH medulloblastoma DJ Merk, J Ohli, ND Merk, V Thatikonda, S Morrissy, M Schoof, ... Developmental cell 44 (6), 709-724. e6, 2018 | 44 | 2018 |
A robust, GFP-orthogonal photoswitchable inhibitor scaffold extends optical control over the microtubule cytoskeleton L Gao, JCM Meiring, Y Kraus, M Wranik, T Weinert, SD Pritzl, R Bingham, ... Cell Chemical Biology 28 (2), 228-241. e6, 2021 | 43 | 2021 |
Pyrrole Hemithioindigo Antimitotics with Near‐Quantitative Bidirectional Photoswitching that Photocontrol Cellular Microtubule Dynamics with Single‐Cell Precision A Sailer, JCM Meiring, C Heise, LN Pettersson, A Akhmanova, ... Angewandte Chemie International Edition 60 (44), 23695-23704, 2021 | 42 | 2021 |
Hemithioindigos for cellular photopharmacology: desymmetrised molecular switch scaffolds enabling design control over the isomer‐dependency of potent antimitotic bioactivity A Sailer, F Ermer, Y Kraus, FH Lutter, C Donau, M Bremerich, J Ahlfeld, ... ChemBioChem 20 (10), 1305-1314, 2019 | 42 | 2019 |
Dynamic changes in circulating T follicular helper cell composition predict neutralising antibody responses after yellow fever vaccination JE Huber, J Ahlfeld, MK Scheck, M Zaucha, K Witter, L Lehmann, ... Clinical & translational immunology 9 (5), e1129, 2020 | 41 | 2020 |
Wnt/β-catenin signaling inhibits the Shh pathway and impairs tumor growth in Shh-dependent medulloblastoma J Pöschl, M Bartels, J Ohli, E Bianchi, K Kuteykin-Teplyakov, D Grammel, ... Acta neuropathologica 127, 605-607, 2014 | 37 | 2014 |
Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer P Metzger, SV Kirchleitner, M Kluge, LM Koenig, C Hörth, ... Journal for immunotherapy of cancer 7, 1-16, 2019 | 34 | 2019 |
In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P … L Gao, JCM Meiring, A Varady, IE Ruider, C Heise, M Wranik, CD Velasco, ... Journal of the American Chemical Society 144 (12), 5614-5628, 2022 | 33 | 2022 |
Selective, modular probes for thioredoxins enabled by rational tuning of a unique disulfide structure motif JG Felber, L Zeisel, L Poczka, K Scholzen, S Busker, MS Maier, ... Journal of the American Chemical Society 143 (23), 8791-8803, 2021 | 33 | 2021 |
Potent hemithioindigo-based antimitotics photocontrol the microtubule cytoskeleton in cellulo A Sailer, F Ermer, Y Kraus, R Bingham, FH Lutter, J Ahlfeld, ... Beilstein Journal of Organic Chemistry 16 (1), 125-134, 2020 | 28 | 2020 |
A novel complete autosomal-recessive STAT1 LOF variant causes immunodeficiency with hemophagocytic lymphohistiocytosis–like hyperinflammation DFR Boehmer, LM Koehler, T Magg, P Metzger, M Rohlfs, J Ahlfeld, ... The Journal of Allergy and Clinical Immunology: In Practice 8 (9), 3102-3111, 2020 | 26 | 2020 |
Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically JG Felber, L Poczka, KC Scholzen, L Zeisel, MS Maier, S Busker, ... Nature Communications 13 (1), 1754, 2022 | 25 | 2022 |
Sources of calretinin inputs to motoneurons of extraocular muscles involved in upgaze J Ahlfeld, M Mustari, AKE Horn Annals of the New York Academy of Sciences 1233 (1), 91-99, 2011 | 23 | 2011 |