| A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification TI Brelidze, X Niu, KL Magleby Proceedings of the National Academy of Sciences 100 (15), 9017-9022, 2003 | 178 | 2003 |
| Structure of the carboxy-terminal region of a KCNH channel TI Brelidze, AE Carlson, B Sankaran, WN Zagotta Nature 481 (7382), 530-533, 2012 | 129 | 2012 |
| Absence of direct cyclic nucleotide modulation of mEAG1 and hERG1 channels revealed with fluorescence and electrophysiological methods TI Brelidze, AE Carlson, WN Zagotta Journal of Biological Chemistry 284 (41), 27989-27997, 2009 | 114 | 2009 |
| Structure of the C-terminal region of an ERG channel and functional implications TI Brelidze, EC Gianulis, F DiMaio, MC Trudeau, WN Zagotta Proceedings of the National Academy of Sciences 110 (28), 11648-11653, 2013 | 72 | 2013 |
| Probing the geometry of the inner vestibule of BK channels with sugars TI Brelidze, KL Magleby The Journal of general physiology 126 (2), 105-121, 2005 | 59 | 2005 |
| Ring of Negative Charge in BK Channels Facilitates Block by Intracellular Mg2+ and Polyamines through Electrostatics Y Zhang, X Niu, TI Brelidze, KL Magleby The Journal of general physiology 128 (2), 185-202, 2006 | 56 | 2006 |
| Protons Block BK Channels by Competitive Inhibition with K+ and Contribute to the Limits of Unitary Currents at High Voltages TI Brelidze, KL Magleby The Journal of general physiology 123 (3), 305-319, 2004 | 37 | 2004 |
| Flavonoid regulation of EAG1 channels AE Carlson, TI Brelidze, WN Zagotta Journal of General Physiology 141 (3), 347-358, 2013 | 36 | 2013 |
| The HCN domain is required for HCN channel cell-surface expression and couples voltage-and cAMP-dependent gating mechanisms ZJ Wang, I Blanco, S Hayoz, TI Brelidze Journal of Biological Chemistry 295 (24), 8164-8173, 2020 | 20 | 2020 |
| Chlorpromazine binding to the PAS domains uncovers the effect of ligand modulation on EAG channel activity ZJ Wang, SM Soohoo, PB Tiwari, G Piszczek, TI Brelidze Journal of Biological Chemistry 295 (13), 4114-4123, 2020 | 20 | 2020 |
| Investigating cyclic nucleotide and cyclic dinucleotide binding to HCN channels by surface plasmon resonance S Hayoz, PB Tiwari, G Piszczek, A Üren, TI Brelidze PLoS One 12 (9), e0185359, 2017 | 17 | 2017 |
| Flavonoid regulation of HCN2 channels AE Carlson, JC Rosenbaum, TI Brelidze, RE Klevit, WN Zagotta Journal of Biological Chemistry 288 (46), 33136-33145, 2013 | 15 | 2013 |
| Identifying regulators for EAG1 channels with a novel electrophysiology and tryptophan fluorescence based screen TI Brelidze, AE Carlson, DR Davies, LJ Stewart, WN Zagotta PLoS One 5 (9), e12523, 2010 | 15 | 2010 |
| Liposome-DNA interaction: microcalorimetric study GM Mrevlishvili, BI Kankia, TJ Mdzinarashvili, TI Brelidze, ... Chemistry and physics of lipids 94 (1), 139-143, 1998 | 15 | 1998 |
| Multifaceted effect of chlorpromazine in cancer: Implications for cancer treatment P Kamgar-Dayhoff, TI Brelidze Oncotarget 12 (14), 1406, 2021 | 12 | 2021 |
| Placental vascular remodeling in pregnant women with COVID-19 SG Gychka, TI Brelidze, IL Kuchyn, TV Savchuk, SI Nikolaienko, ... PloS one 17 (7), e0268591, 2022 | 9 | 2022 |
| Protein redox state monitoring studies of thiol reactivity YJ Suzuki, L Marcocci, T Shimomura, Y Tatenaka, Y Ohuchi, TI Brelidze Antioxidants 8 (5), 143, 2019 | 8 | 2019 |
| Increased smooth muscle Kv11. 1 channel expression in pulmonary hypertension and protective role of Kv11. 1 channel blocker dofetilide NV Shults, V Rybka, YJ Suzuki, TI Brelidze The American Journal of Pathology 190 (1), 48-56, 2020 | 7 | 2020 |
| Identification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels ZJ Wang, PB Tiwari, A Üren, TI Brelidze BMC Pharmacology and Toxicology 20, 1-11, 2019 | 5 | 2019 |
| Investigation of PAS and CNBH domain interactions in hERG channels and effects of long-QT syndrome-causing mutations with surface plasmon resonance SM Soohoo, PB Tiwari, YJ Suzuki, TI Brelidze Journal of Biological Chemistry 298 (1), 2022 | 3 | 2022 |
