Discovery of a pathway for terminal-alkyne amino acid biosynthesis JA Marchand, ME Neugebauer, MC Ing, CI Lin, JG Pelton, MCY Chang Nature 567 (7748), 420-424, 2019 | 147 | 2019 |
A family of radical halogenases for the engineering of amino-acid-based products ME Neugebauer, KH Sumida, JG Pelton, JL McMurry, JA Marchand, ... Nature chemical biology 15 (10), 1009-1016, 2019 | 97 | 2019 |
Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity ME Neugebauer, A Hsu, M Arbab, NA Krasnow, AN McElroy, S Pandey, ... Nature biotechnology 41 (5), 673-685, 2023 | 71 | 2023 |
Phage-assisted evolution and protein engineering yield compact, efficient prime editors JL Doman, S Pandey, ME Neugebauer, M An, JR Davis, PB Randolph, ... Cell 186 (18), 3983-4002. e26, 2023 | 40 | 2023 |
Reaction pathway engineering converts a radical hydroxylase into a halogenase ME Neugebauer, EN Kissman, JA Marchand, JG Pelton, NA Sambold, ... Nature chemical biology 18 (2), 171-179, 2022 | 31 | 2022 |
Substrate-Triggered μ-Peroxodiiron(III) Intermediate in the 4-Chloro-l-Lysine-Fragmenting Heme-Oxygenase-like Diiron Oxidase (HDO) BesC: Substrate … MJ McBride, MA Nair, D Sil, JW Slater, ME Neugebauer, MCY Chang, ... Biochemistry 61 (8), 689-702, 2022 | 12 | 2022 |
Biocatalytic control of site-selectivity and chain length-selectivity in radical amino acid halogenases EN Kissman, ME Neugebauer, KH Sumida, CV Swenson, NA Sambold, ... Proceedings of the National Academy of Sciences 120 (12), e2214512120, 2023 | 7 | 2023 |
Synergistic Binding of the Halide and Cationic Prime Substrate of the L-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States JW Slater, ME Neugebauer, MJ McBride, D Sil, CY Lin, BJ Katch, AK Boal, ... bioRxiv, 2023.05. 02.539147, 2023 | 1 | 2023 |
Biosynthesis of bioorthogonal amino acids MCY Chang, JAM Benmaman, ME Neugebauer US Patent 11,098,336, 2021 | | 2021 |
Biosynthesis of bioorthogonal amino acids MCY Chang, JAM BENMAMAN, ME NEUGEBAUER | | 2018 |
Synthetic biology approaches to biorthogonal chemistry M Chang, J Marchand, M Neugebauer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |