The C9orf72 repeat expansion disrupts nucleocytoplasmic transport K Zhang, CJ Donnelly, AR Haeusler, JC Grima, JB Machamer, ... Nature 525 (7567), 56-61, 2015 | 1035 | 2015 |
Stress granule assembly disrupts nucleocytoplasmic transport K Zhang, JG Daigle, KM Cunningham, AN Coyne, K Ruan, JC Grima, ... Cell 173 (4), 958-971. e17, 2018 | 360 | 2018 |
Mutant huntingtin disrupts the nuclear pore complex JC Grima, JG Daigle, N Arbez, KC Cunningham, K Zhang, J Ochaba, ... Neuron 94 (1), 93-107. e6, 2017 | 323 | 2017 |
FIG4 regulates lysosome membrane homeostasis independent of phosphatase function R Bharadwaj, KM Cunningham, K Zhang, TE Lloyd Human molecular genetics 25 (4), 681-692, 2016 | 52 | 2016 |
TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS KM Cunningham, K Maulding, K Ruan, M Senturk, JC Grima, H Sung, ... Elife 9, e59419, 2020 | 48 | 2020 |
Neuroglian regulates Drosophila intestinal stem cell proliferation through enhanced signaling via the epidermal growth factor receptor M Resnik-Docampo, KM Cunningham, SM Ruvalcaba, C Choi, V Sauer, ... Stem cell reports 16 (6), 1584-1597, 2021 | 9 | 2021 |
Synthesis and biological evaluation of triazole-vanillin molecular hybrids as anti-cancer agents G VM Sharma, K S Kumar, S V Reddy, A Nagalingam, K M Cunningham, ... Current Bioactive Compounds 13 (3), 223-235, 2017 | 5 | 2017 |
NOT gated T cells that selectively target EGFR and other widely expressed tumor antigens J Oh, C Kirsh, JP Hsin, KC Radecki, A Zampieri, D Manry, Y Ando, S Miller, ... Iscience 27 (6), 2024 | | 2024 |
NUCLEOCYTOPLASMIC TRANSPORT DISRUPTION LEADS TO AUTOPHAGY AND LYSOSOME DEFECTS IN A DROSOPHILA MODEL OF C9ORF72 HEXANUCLEOTIDE REPEAT EXPANSION MEDIATED ALS AND FTD KM Cunningham Johns Hopkins University, 2019 | | 2019 |
TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9ORF72-mediated ALS/FTD KM Cunningham, K Zhang, H Sung, JT Pham, M Senturk, J Rothstein, ... MOLECULAR BIOLOGY OF THE CELL 29 (26), 341-342, 2018 | | 2018 |
Mechanisms of Neurodegeneration in C9ORF72-Mediated ALS/FTD K Cunningham, K Zhang, H Sung, M Senterk, JD Rothstein, H Bellen, ... ANNALS OF NEUROLOGY 84, S214-S215, 2018 | | 2018 |
Autophagolysosome disruption in Drosophila models of ALS/FTD caused by C9orf72 mutations. KM Cunningham, K Zhang, M Senturk, H Sung, K Ruan, Z Zuo, HJ Bellen, ... MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
Mechanism of Cytoplasmic Protein Aggregation and Neurodegeneration in Drosophila Models of C9-ALS/FTD K Zhang, K Cunningham, J Grima, JD Rothstein, TE Lloyd ANNALS OF NEUROLOGY 80, S150-S150, 2016 | | 2016 |
Relationship of proteostasis and nucleocytoplasmic transport in neurodegenerative diseases. K Zhang, K Cunningham, K Ruan, J Grima, G Daigle, J Rothstein, ... MOLECULAR BIOLOGY OF THE CELL 27, 2016 | | 2016 |
Autophagy protects against neurodegeneration in a Drosophila model of C9orf72-mediated ALS K Zhang, K Cunningham, JB Machamer, TE Lloyd MOLECULAR BIOLOGY OF THE CELL 25, 2014 | | 2014 |