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Zeneng Wang
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Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
Z Wang, E Klipfell, BJ Bennett, R Koeth, BS Levison, B DuGar, ...
nature 472 (7341), 57-63, 2011
57592011
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis
RA Koeth, Z Wang, BS Levison, JA Buffa, E Org, BT Sheehy, EB Britt, X Fu, ...
Nature medicine 19 (5), 576-585, 2013
47042013
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk
WHW Tang, Z Wang, BS Levison, RA Koeth, EB Britt, X Fu, Y Wu, ...
New England Journal of Medicine 368 (17), 1575-1584, 2013
34792013
Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk
W Zhu, JC Gregory, E Org, JA Buffa, N Gupta, Z Wang, L Li, X Fu, Y Wu, ...
Cell 165 (1), 111-124, 2016
17972016
Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis
Z Wang, AB Roberts, JA Buffa, BS Levison, W Zhu, E Org, X Gu, Y Huang, ...
Cell 163 (7), 1585-1595, 2015
12842015
Gut Microbiota-Dependent Trimethylamine N-Oxide (TMAO) Pathway Contributes to Both Development of Renal Insufficiency and Mortality Risk in Chronic Kidney …
WHW Tang, Z Wang, DJ Kennedy, Y Wu, JA Buffa, B Agatisa-Boyle, XS Li, ...
Circulation research 116 (3), 448-455, 2015
11472015
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation
BJ Bennett, TQ de Aguiar Vallim, Z Wang, DM Shih, Y Meng, J Gregory, ...
Cell metabolism 17 (1), 49-60, 2013
10562013
Protein carbamylation links inflammation, smoking, uremia and atherogenesis
Z Wang, SJ Nicholls, ER Rodriguez, O Kummu, S Hörkkö, J Barnard, ...
Nature medicine 13 (10), 1176-1184, 2007
8082007
Trimethylamine N‐oxide promotes vascular inflammation through signaling of mitogen‐activated protein kinase and nuclear factor‐κB
MM Seldin, Y Meng, H Qi, WF Zhu, Z Wang, SL Hazen, AJ Lusis, DM Shih
Journal of the American Heart Association 5 (2), e002767, 2016
7922016
Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure: Refining the Gut Hypothesis
WHW Tang, Z Wang, Y Fan, B Levison, JE Hazen, LM Donahue, Y Wu, ...
Journal of the American College of Cardiology 64 (18), 1908-1914, 2014
7342014
Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide
Z Wang, WHW Tang, JA Buffa, X Fu, EB Britt, RA Koeth, BS Levison, ...
European heart journal 35 (14), 904-910, 2014
6242014
γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO
RA Koeth, BS Levison, MK Culley, JA Buffa, Z Wang, JC Gregory, E Org, ...
Cell metabolism 20 (5), 799-812, 2014
5552014
Transmission of atherosclerosis susceptibility with gut microbial transplantation
JC Gregory, JA Buffa, E Org, Z Wang, BS Levison, W Zhu, MA Wagner, ...
Journal of Biological Chemistry 290 (9), 5647-5660, 2015
5312015
Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors
XS Li, S Obeid, R Klingenberg, B Gencer, F Mach, L Räber, S Windecker, ...
European heart journal 38 (11), 814-824, 2017
4852017
Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential
AB Roberts, X Gu, JA Buffa, AG Hurd, Z Wang, W Zhu, N Gupta, SM Skye, ...
Nature medicine 24 (9), 1407-1417, 2018
4692018
Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women
Z Wang, N Bergeron, BS Levison, XS Li, S Chiu, X Jia, RA Koeth, L Li, ...
European heart journal 40 (7), 583-594, 2019
4212019
The TMAO-generating enzyme flavin monooxygenase 3 is a central regulator of cholesterol balance
M Warrier, DM Shih, AC Burrows, D Ferguson, AD Gromovsky, AL Brown, ...
Cell reports 10 (3), 326-338, 2015
4152015
An abundant dysfunctional apolipoprotein A1 in human atheroma
Y Huang, JA DiDonato, BS Levison, D Schmitt, L Li, Y Wu, J Buffa, T Kim, ...
Nature medicine 20 (2), 193-203, 2014
4142014
Gut microbiota derived metabolites in cardiovascular health and disease
Z Wang, Y Zhao
Protein & Cell 9 (5), 416-431, 2018
3652018
Choline diet and its gut microbe–derived metabolite, trimethylamine N-oxide, exacerbate pressure overload–induced heart failure
CL Organ, H Otsuka, S Bhushan, Z Wang, J Bradley, R Trivedi, ...
Circulation: Heart Failure 9 (1), e002314, 2016
3642016
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