| Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells CA Tsuchida, N Brandes, R Bueno, M Trinidad, T Mazumder, B Yu, ... Cell 186 (21), 4567-4582. e20, 2023 | 39 | 2023 |
| Precise transcript targeting by CRISPR-Csm complexes D Colognori, M Trinidad, JA Doudna Nature biotechnology 41 (9), 1256-1264, 2023 | 34 | 2023 |
| Improved genome editing by an engineered CRISPR-Cas12a E Ma, K Chen, H Shi, EC Stahl, B Adler, M Trinidad, J Liu, K Zhou, J Ye, ... Nucleic Acids Research 50 (22), 12689-12701, 2022 | 30 | 2022 |
| Decorating chromatin for enhanced genome editing using CRISPR-Cas9 E Chen, E Lin-Shiao, M Trinidad, M Saffari Doost, D Colognori, ... Proceedings of the National Academy of Sciences 119 (49), e2204259119, 2022 | 20 | 2022 |
| In vivo human T cell engineering with enveloped delivery vehicles JR Hamilton, E Chen, BS Perez, CR Sandoval Espinoza, MH Kang, ... Nature Biotechnology, 1-9, 2024 | 12* | 2024 |
| Identifying therapeutic drug targets using bidirectional effect genes K Estrada, S Froelich, A Wuster, CR Bauer, T Sterling, WT Clark, Y Ru, ... Nature Communications 12 (1), 2224, 2021 | 12 | 2021 |
| Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs EC Stahl, JK Sabo, MH Kang, R Allen, E Applegate, SE Kim, Y Kwon, ... Molecular Therapy 31 (8), 2422-2438, 2023 | 8 | 2023 |
| Predicting disease severity in metachromatic leukodystrophy using protein activity and a patient phenotype matrix M Trinidad, X Hong, S Froelich, J Daiker, J Sacco, HP Nguyen, ... Genome Biology 24 (1), 172, 2023 | 7 | 2023 |
| CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes BA Adler, MI Trinidad, D Bellieny-Rabelo, E Zhang, HM Karp, ... Nucleic acids research 52 (D1), D590-D596, 2024 | 5 | 2024 |
| Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes PH Yoon, P Skopintsev, H Shi, LX Chen, BA Adler, M Al-Shimary, ... Nucleic Acids Research 51 (22), 12414-12427, 2023 | 5 | 2023 |
| Engineering self-deliverable ribonucleoproteins for genome editing in the brain K Chen, EC Stahl, MH Kang, B Xu, R Allen, M Trinidad, JA Doudna Nature Communications 15 (1), 1727, 2024 | 4 | 2024 |
| Genome-wide Characterization of Diverse Bacteriophages Enabled by RNA-Binding CRISPRi BA Adler, MJ Al-Shimary, JR Patel, E Ambruster, D Colognori, EJ Charles, ... bioRxiv, 2023.09. 18.558157, 2023 | 4 | 2023 |
| High-throughput discovery of SLC6A1 variants affecting GABA transport in neurological disorders M Trinidad, S Froelich, G Berguig, W Wallace, L Bomba, JH LeBowitz, ... Neurology 22 (1807), 10.1101, 2022 | 4 | 2022 |
| Identifying therapeutic drug targets for rare and common forms of short stature K Estrada, S Froelich, A Wuster, CR Bauer, T Sterling, WT Clark, Y Ru, ... bioRxiv, 2020.04. 02.022624, 2020 | 4 | 2020 |
| Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9 AR Eggers, K Chen, KM Soczek, OT Tuck, EE Doherty, B Xu, MI Trinidad, ... Cell, 2024 | 2 | 2024 |
| SLC6A1 variant pathogenicity, molecular function and phenotype: a genetic and clinical analysis A Stefanski, E Pérez-Palma, T Brünger, L Montanucci, C Gati, C Klöckner, ... Brain 146 (12), 5198-5208, 2023 | 2 | 2023 |
| eIF3 engages with 3’-UTR termini of highly translated mRNAs in neural progenitor cells S Mestre-Fos, L Ferguson, M Trinidad, NT Ingolia, JHD Cate bioRxiv, 2023 | 2 | 2023 |
| Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP K Chen, H Han, S Zhao, B Xu, B Yin, M Trinidad, BW Burgstone, N Murthy, ... bioRxiv, 2023.11. 15.566339, 2023 | 2 | 2023 |
| Targeted phosphoproteomics of the Ras signaling network reveal regulatory mechanisms mediated by oncogenic KRAS A Urisman, TL Yuan, M Trinidad, JH Morris, S Afghani, JA Oses-Prieto, ... bioRxiv, 695460, 2019 | 2 | 2019 |
| RNA language models predict mutations that improve RNA function Y Shulgina, MI Trinidad, CJ Langeberg, H Nisonoff, S Chithrananda, ... bioRxiv, 2024 | | 2024 |
Jennifer DoudnaProfessor of Molecular and Cell Biology and Chemistry, UC BerkeleyVerified email at berkeley.edu
