| The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation TE White, A Brandariz-Nuñez, JC Valle-Casuso, S Amie, LA Nguyen, ... Cell host & microbe 13 (4), 441-451, 2013 | 348 | 2013 |
| Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages B Kim, LA Nguyen, W Daddacha, JA Hollenbaugh Journal of Biological Chemistry 287 (26), 21570-21574, 2012 | 242 | 2012 |
| SAMHD1 prevents autoimmunity by maintaining genome stability S Kretschmer, C Wolf, N König, W Staroske, J Guck, M Häusler, H Luksch, ... Annals of the rheumatic diseases 74 (3), e17-e17, 2015 | 169 | 2015 |
| Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1 TE White, A Brandariz-Nuñez, JC Valle-Casuso, S Amie, L Nguyen, B Kim, ... Virology 436 (1), 81-90, 2013 | 166 | 2013 |
| Role of CD44s and CD44v6 on human breast cancer cell adhesion, migration, and invasion A Afify, P Purnell, L Nguyen Experimental and molecular pathology 86 (2), 95-100, 2009 | 161 | 2009 |
| Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response R Behrendt, T Schumann, A Gerbaulet, LA Nguyen, N Schubert, ... Cell reports 4 (4), 689-696, 2013 | 160 | 2013 |
| Ribonucleoside triphosphates as substrate of human immunodeficiency virus type 1 reverse transcriptase in human macrophages EM Kennedy, C Gavegnano, L Nguyen, R Slater, A Lucas, E Fromentin, ... Journal of biological chemistry 285 (50), 39380-39391, 2010 | 118 | 2010 |
| Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors Y Yang, D Kang, LA Nguyen, ZB Smithline, C Pannecouque, P Zhan, ... Elife 7, e36340, 2018 | 66 | 2018 |
| Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect A Bhattacharya, Z Wang, T White, C Buffone, LA Nguyen, CN Shepard, ... Scientific reports 6 (1), 31353, 2016 | 66 | 2016 |
| Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells HM Baldauf, L Stegmann, SM Schwarz, I Ambiel, M Trotard, M Martin, ... Proceedings of the National Academy of Sciences 114 (10), 2729-2734, 2017 | 54 | 2017 |
| Crystal structure of Pistol, a class of self-cleaving ribozyme LA Nguyen, J Wang, TA Steitz Proceedings of the National Academy of Sciences 114 (5), 1021-1026, 2017 | 54 | 2017 |
| Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1 A Brandariz-Nuñez, JC Valle-Casuso, TE White, L Nguyen, ... Retrovirology 10, 1-12, 2013 | 49 | 2013 |
| A bivalent Epstein-Barr virus vaccine induces neutralizing antibodies that block infection and confer immunity in humanized mice CJ Wei, W Bu, LA Nguyen, JD Batchelor, JH Kim, S Pittaluga, JR Fuller, ... Science translational medicine 14 (643), eabf3685, 2022 | 45 | 2022 |
| Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supply L Dragin, LA Nguyen, H Lahouassa, A Sourisce, B Kim, BC Ramirez, ... Retrovirology 10, 1-11, 2013 | 43 | 2013 |
| Functionality of redox-active cysteines is required for restriction of retroviral replication by SAMHD1 Z Wang, A Bhattacharya, T White, C Buffone, A McCabe, LA Nguyen, ... Cell reports 24 (4), 815-823, 2018 | 26 | 2018 |
| SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells R Zhang, N Bloch, LA Nguyen, B Kim, NR Landau PLoS One 9 (2), e89558, 2014 | 26 | 2014 |
| Host SAMHD1 protein promotes HIV-1 recombination in macrophages LA Nguyen, DH Kim, MB Daly, KC Allan, B Kim Journal of Biological Chemistry 289 (5), 2489-2496, 2014 | 23 | 2014 |
| Effect of ribonucleotides embedded in a DNA template on HIV-1 reverse transcription kinetics and fidelity W Daddacha, E Noble, LA Nguyen, EM Kennedy, B Kim Journal of Biological Chemistry 288 (18), 12522-12532, 2013 | 14 | 2013 |
| Altered strand transfer activity of a multiple-drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutant with a dipeptide fingers domain insertion LA Nguyen, W Daddacha, S Rigby, RA Bambara, B Kim Journal of molecular biology 415 (2), 248-262, 2012 | 7 | 2012 |
| Pre-steady state kinetic analysis of HIV-1 reverse transcriptase for non-canonical ribonucleoside triphosphate incorporation and DNA synthesis from ribonucleoside-containing … LA Nguyen, RA Domaoal, EM Kennedy, DH Kim, RF Schinazi, B Kim Antiviral research 115, 75-82, 2015 | 6 | 2015 |
