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Jen-Yu Liao
Jen-Yu Liao
Alnylam Pharmaceuticals
Verified email at uci.edu
Title
Cited by
Cited by
Year
Synthesis and evolution of a threose nucleic acid aptamer bearing 7-deaza-7-substituted guanosine residues
H Mei, JY Liao, RM Jimenez, Y Wang, S Bala, C McCloskey, C Switzer, ...
Journal of the American Chemical Society 140 (17), 5706-5713, 2018
872018
Evaluating TNA stability under simulated physiological conditions
MC Culbertson, KW Temburnikar, SP Sau, JY Liao, S Bala, JC Chaput
Bioorganic & medicinal chemistry letters 26 (10), 2418-2421, 2016
722016
A Scalable Synthesis of α-l-Threose Nucleic Acid Monomers
SP Sau, NE Fahmi, JY Liao, S Bala, JC Chaput
The Journal of organic chemistry 81 (6), 2302-2307, 2016
642016
A tool for the import of natural and unnatural nucleoside triphosphates into bacteria
AW Feldman, EC Fischer, MP Ledbetter, JY Liao, JC Chaput, ...
Journal of the American Chemical Society 140 (4), 1447-1454, 2018
432018
P (V) Reagents for the Scalable Synthesis of Natural and Modified Nucleoside Triphosphates
JY Liao, S Bala, AK Ngor, EJ Yik, JC Chaput
Journal of the American Chemical Society 141 (34), 13286-13289, 2019
332019
Structural insights into conformation differences between DNA/TNA and RNA/TNA chimeric duplexes
I Anosova, EA Kowal, NJ Sisco, S Sau, J Liao, S Bala, E Rozners, M Egli, ...
ChemBioChem 17 (18), 1705-1708, 2016
332016
Ligase-Mediated Threose Nucleic Acid Synthesis on DNA Templates
CM McCloskey, J Liao, S Bala, JC Chaput
ACS synthetic biology, 2019
232019
Synthesis of α-l-Threofuranosyl Nucleoside 3′-Monophosphates, 3′-Phosphoro(2-Methyl)imidazolides, and 3′-Triphosphates
S Bala, JY Liao, H Mei, JC Chaput
The Journal of organic chemistry 82 (11), 5910-5916, 2017
232017
Multistep divergent synthesis of benzimidazole linked benzoxazole/benzothiazole via copper catalyzed domino annulation
JY Liao, M Selvaraju, CH Chen, CM Sun
Organic & biomolecular chemistry 11 (15), 2473-2481, 2013
192013
Regioselective Synthesis of Angular Isocoumarinselenazoles: A Benzoselenazole‐directed, Site‐specific, Ruthenium‐catalyzed C(sp2)‐H Activation
S Dhole, JY Liao, S Kumar, DB Salunke, CM Sun
Advanced Synthesis & Catalysis 360 (5), 942-950, 2018
92018
A parallel stranded G‐quadruplex composed of threose nucleic acid (TNA)
J Liao, I Anosova, S Bala, WD Van Horn, JC Chaput
Biopolymers 107 (3), 2017
92017
Synthesis of 2′-Deoxy-α-l-threofuranosyl Nucleoside Triphosphates
S Bala, JY Liao, L Zhang, CN Tran, N Chim, JC Chaput
The Journal of organic chemistry 83 (16), 8840-8850, 2018
62018
Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small …
S Matsuda, S Bala, JY Liao, D Datta, A Mikami, L Woods, JM Harp, ...
Journal of the American Chemical Society, 2023
52023
Compositions and Methods for Synthesis of Phosphorylated Molecules
J Chaput, J Liao, S Bala
US Patent App. 16/374,795, 2020
2020
Synthesis of α‑L‑Threose Monomers and Polymers for Therapeutic and Diagnostic Applications
JY Liao
UC Irvine, 2018
2018
Developing a pipeline for generating TNA-phosphoramidite and TNA-triphosphate monomers for the in vitro evaluation of the properties of the polymers
S Bala, JY Liao, J Chaput
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Back Cover: Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes (ChemBioChem 18/2016)
I Anosova, EA Kowal, NJ Sisco, S Sau, J Liao, S Bala, E Rozners, M Egli, ...
ChemBioChem 17 (18), 1785-1785, 2016
2016
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