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Ibrahim Akkouh
Ibrahim Akkouh
University of Oslo, Oslo University Hospital
Verified email at medisin.uio.no
Title
Cited by
Cited by
Year
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
IA Akkouh, T Ueland, L Hansson, E Inderhaug, T Hughes, NE Steen, ...
Brain, behavior, and immunity 87, 634-644, 2020
602020
Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
S Wang, JR van Rhijn, I Akkouh, N Kogo, N Maas, A Bleeck, IS Ortiz, ...
Cell reports 39 (5), 2022
422022
Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders
JR Osete, IA Akkouh, DR de Assis, A Szabo, E Frei, T Hughes, ...
Molecular Psychiatry 26 (11), 6789-6805, 2021
382021
Exploring lithium’s transcriptional mechanisms of action in bipolar disorder: a multi-step study
IA Akkouh, S Skrede, A Holmgren, KM Ersland, L Hansson, S Bahrami, ...
Neuropsychopharmacology 45 (6), 947-955, 2020
352020
Systemic cell adhesion molecules in severe mental illness: potential role of intercellular CAM-1 in linking peripheral and neuroinflammation
MA Sheikh, KS O’Connell, T Lekva, A Szabo, IA Akkouh, JR Osete, ...
Biological psychiatry 93 (2), 187-196, 2023
312023
Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia
IA Akkouh, T Hughes, VM Steen, JC Glover, OA Andreassen, S Djurovic, ...
Brain, behavior, and immunity 94, 235-244, 2021
272021
Derivation and molecular characterization of a morphological subpopulation of human iPSC astrocytes reveal a potential role in schizophrenia and clozapine response
IA Akkouh, H Hribkova, M Grabiec, E Budinska, A Szabo, T Kasparek, ...
Schizophrenia bulletin 48 (1), 190-198, 2022
262022
A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia
A Szabo, IA Akkouh, M Vandenberghe, JR Osete, T Hughes, V Heine, ...
Translational psychiatry 11 (1), 554, 2021
192021
Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids
JR Osete, IA Akkouh, O Ievglevskyi, M Vandenberghe, DR de Assis, ...
Molecular Psychiatry 28 (7), 3033-3043, 2023
162023
Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance
IA Akkouh, T Ueland, OA Andreassen, HR Brattbakk, VM Steen, T Hughes, ...
Scientific reports 8 (1), 12654, 2018
162018
All-optical electrophysiology in hiPSC-derived neurons with synthetic voltage sensors
F Puppo, S Sadegh, CA Trujillo, M Thunemann, EP Campbell, ...
Frontiers in Cellular Neuroscience 15, 671549, 2021
122021
Elevated systemic levels of markers reflecting intestinal barrier dysfunction and inflammasome activation are correlated in severe mental illness
SB Jensen, MA Sheikh, IA Akkouh, A Szabo, KS O’Connell, T Lekva, ...
Schizophrenia bulletin 49 (3), 635-645, 2023
112023
Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia
KS O'Connell, E Koch, HÇ Lenk, IA Akkouh, G Hindley, P Jaholkowski, ...
Psychiatry research 325, 115217, 2023
82023
Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort
F Krull, I Akkouh, T Hughes, F Bettella, L Athanasiu, OB Smeland, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 112, 110408, 2022
82022
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
A Szabo, IA Akkouh, T Ueland, TV Lagerberg, I Dieset, T Bjella, P Aukrust, ...
Frontiers in Psychiatry 11, 642, 2020
72020
Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations
T Hughes, L Hansson, I Akkouh, R Hajdarevic, JS Bringsli, A Torsvik, ...
Scientific Reports 10 (1), 9101, 2020
72020
Increased ferroptosis in leukocytes from preeclamptic women involving the long non‐coding taurine upregulated gene 1 (TUG1)
T Lekva, AE Michelsen, MCP Roland, ER Norwitz, ME Estensen, ...
Journal of Internal Medicine 295 (2), 181-195, 2024
62024
Longitudinal transcriptomic analysis of human cortical spheroids identifies axonal dysregulation in the prenatal brain as a mediator of genetic risk for schizophrenia
IA Akkouh, T Ueland, A Szabo, T Hughes, OB Smeland, OA Andreassen, ...
Biological Psychiatry 95 (7), 687-698, 2024
42024
Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain
LS Sæther, A Szabo, IA Akkouh, B Haatveit, C Mohn, A Vaskinn, ...
Brain, Behavior, and Immunity 118, 287-299, 2024
32024
Bipolar patients display stoichiometric imbalance of gene expression in post-mortem brain samples
A Holmgren, I Akkouh, KS O’Connell, JR Osete, PM Bjørnstad, S Djurovic, ...
Molecular Psychiatry, 1-11, 2024
22024
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