VIB-KU Leuven Center for Cancer Biology
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Aberrant methylation of t RNA s links cellular stress to neuro‐developmental disorders
S Blanco, S Dietmann, JV Flores, S Hussain, C Kutter, P Humphreys, ...
The EMBO journal 33 (18), 2020-2039, 2014
Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy
AR Cantelmo, LC Conradi, A Brajic, J Goveia, J Kalucka, A Pircher, ...
Cancer cell 30 (6), 968-985, 2016
Endothelial cell metabolism
G Eelen, P de Zeeuw, L Treps, U Harjes, BW Wong, P Carmeliet
Physiological reviews 98 (1), 3-58, 2018
Glioblastoma stem-like cells secrete the pro-angiogenic VEGF-A factor in extracellular vesicles
L Treps, R Perret, S Edmond, D Ricard, J Gavard
Journal of extracellular vesicles 6 (1), 1359479, 2017
Endothelial cell metabolism in health and disease: impact of hypoxia
BW Wong, E Marsch, L Treps, M Baes, P Carmeliet
The EMBO journal 36 (15), 2187-2203, 2017
Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation
A Le Guelte, EM Galan-Moya, J Dwyer, L Treps, G Kettler, JK Hebda, ...
Journal of cell science 125 (17), 4137-4146, 2012
Extracellular vesicle-transported Semaphorin3A promotes vascular permeability in glioblastoma
L Treps, S Edmond, E Harford-Wright, EM Galan-Moya, A Schmitt, S Azzi, ...
Oncogene 35 (20), 2615-2623, 2016
Quiescent endothelial cells upregulate fatty acid β-oxidation for vasculoprotection via redox homeostasis
J Kalucka, L Bierhansl, NV Conchinha, R Missiaen, I Elia, U Brüning, ...
Cell metabolism 28 (6), 881-894. e13, 2018
Impairment of angiogenesis by fatty acid synthase inhibition involves mTOR malonylation
U Bruning, F Morales-Rodriguez, J Kalucka, J Goveia, F Taverna, ...
Cell metabolism 28 (6), 866-880. e15, 2018
Endothelial cell metabolism: a novel player in atherosclerosis? Basic principles and therapeutic opportunities
A Pircher, L Treps, N Bodrug, P Carmeliet
Atherosclerosis 253, 247-257, 2016
Single-cell transcriptome atlas of murine endothelial cells
J Kalucka, LPMH de Rooij, J Goveia, K Rohlenova, SJ Dumas, E Meta, ...
Cell 180 (4), 764-779. e20, 2020
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis
G Eelen, C Dubois, AR Cantelmo, J Goveia, U Brüning, M DeRan, ...
Nature 561 (7721), 63-69, 2018
Central role of metabolism in endothelial cell function and vascular disease
L Bierhansl, LC Conradi, L Treps, M Dewerchin, P Carmeliet
Physiology 32 (2), 126-140, 2017
Manipulating angiogenesis by targeting endothelial metabolism: hitting the engine rather than the drivers—a new perspective?
L Treps, LC Conradi, U Harjes, P Carmeliet
Pharmacological Reviews 68 (3), 872-887, 2016
Pharmacological targeting of apelin impairs glioblastoma growth
E Harford-Wright, G Andre-Gregoire, KA Jacobs, L Treps, S Le Gonidec, ...
Brain 140 (11), 2939-2954, 2017
The guanine exchange factor SWAP70 mediates vGPCR-induced endothelial plasticity.
GJ Dwyer J, Azzi S, Leclair HM, Georges S, Carlotti A, Treps L, Galan-Moya ...
Cell Commun Signal 13 ((1):11), 2015
An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates
J Goveia, K Rohlenova, F Taverna, L Treps, LC Conradi, A Pircher, ...
Cancer Cell 37 (1), 21-36. e13, 2020
Emerging roles of Semaphorins in the regulation of epithelial and endothelial junctions
L Treps, A Le Guelte, J Gavard
Tissue barriers 1 (1), e23272, 2013
EndoDB: a database of endothelial cell transcriptomics data
S Khan, F Taverna, K Rohlenova, L Treps, V Geldhof, L de Rooij, L Sokol, ...
Nucleic acids research 47 (D1), D736-D744, 2019
Endothelial secreted factors suppress mitogen deprivation-induced autophagy and apoptosis in glioblastoma stem-like cells
EM Galan-Moya, L Treps, L Oliver, H Chneiweiss, FM Vallette, N Bidčre, ...
PloS one 9 (3), e93505, 2014
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